Overcoming tumor necrosis factor and drug resistance of human tumor cell lines by combination treatment with anti-Fas antibody and drugs or toxins.

The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis

1991 • 2,815 citations

Tumor Necrosis Factor (TNF)

1985 • 1,932 citations

A New Approach to the Adoptive Immunotherapy of Cancer with Tumor-Infiltrating Lymphocytes

1986 • 1,787 citations

The Biology of Cachectin/TNF -- A Primary Mediator of the Host Response

1989 • 1,679 citations

Cachectin and tumour necrosis factor as two sides of the same biological coin

1986 • 1,659 citations

Recombinant Human Tumor Necrosis Factor-α: Effects on Proliferation of Normal and Transformed Cells in Vitro

1985 • 1,596 citations

A cell-killing monoclonal antibody (anti-Fas) to a cell surface antigen co-downregulated with the receptor of tumor necrosis factor.

1989 • 1,436 citations

A Receptor for Tumor Necrosis Factor Defines an Unusual Family of Cellular and Viral Proteins

1990 • 977 citations

Molecular cloning and expression of a receptor for human tumor necrosis factor

1990 • 973 citations

Expression and structure of the human NGF receptor

1986 • 956 citations

Molecular cloning and expression of the human 55 kd tumor necrosis factor receptor

1990 • 918 citations

Fibroblast growth enhancing activity of tumor necrosis factor and its relationship to other polypeptide growth factors.

1986 • 674 citations

Criteria for Analyzing Interactions between Biologically Active Agents

1981 • 454 citations

Characterization of the MRC OX40 antigen of activated CD4 positive T lymphocytes--a molecule related to nerve growth factor receptor.

1990 • 375 citations

DNA fragmentation: manifestation of target cell destruction mediated by cytotoxic T-cell lines, lymphotoxin-secreting helper T-cell clones, and cell-free lymphotoxin-containing supernatant.

1986 • 152 citations

The E1b oncogene of adenovirus confers cellular resistance to cytotoxicity of tumor necrosis factor and monoclonal anti-Fas antibody

1991 • 119 citations

Synergistic enhancement by tumor necrosis factor of in vitro cytotoxicity from chemotherapeutic drugs targeted at DNA topoisomerase II.

1987 • 116 citations

Synergistic effect of tumor necrosis factor-alpha- and diphtheria toxin-mediated cytotoxicity in sensitive and resistant human ovarian tumor cell lines.

1991 • 52 citations

Sensitivity of resistant human tumor cell lines to tumor necrosis factor and adriamycin used in combination: correlation between down-regulation of tumor necrosis factor-messenger RNA induction and overcoming resistance.

1992 • 47 citations

Clinical and Immunomodulatory Effects of Combination Immunotherapy with Low- Dose Interleukin 2 and Tumor Necrosis Factor a. in Patients with Advanced Non-Small Cell Lung Cancer: A Phase I Trial

1991 • 42 citations

Synergy is documented in vitro with low-dose recombinant tumor necrosis factor, cisplatin, and doxorubicin in ovarian cancer cells

1990 • 31 citations

Synergistic Cytotoxicity of Recombinant Human TNF and Various Anti-Cancer Drugs

1988 • 25 citations

Phase I Study of a Combination of Recombinant Tumor Necrosis Factor-α and Recombinant Interferon-γ in Cancer Patients

1989 • 22 citations

Recombinant tumour necrosis factor alpha administered subcutaneously or intramuscularly for treatment of advanced malignant disease: a phase I trial

1991 • 18 citations

RICIN-MEDIATED CELL-LYSIS AND APOPTOSIS OF DRUG SENSITIVE AND RESISTANT TUMOR-CELLS

1993 • 12 citations

Cytotoxic activity of synthetic aza alkyl lysophospholipids against drug sensitive and drug resistant human tumor cell lines.

1991 • 10 citations

Monoclonal antibody drug targeting

1987 • 9 citations

Hierarchy of Tumor Cell Sensitivity and Resistance to Cytolysis by TNF, Cytotoxic Cells, Bacterial Toxins, and Cytotoxic Drugs

2015 • 6 citations