Transcriptional repression by Rev-erbA alpha is dependent on the signature motif and helix 5 in the ligand binding domain: silencing does not involve an interaction with N-CoR

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

The Steroid and Thyroid Hormone Receptor Superfamily

1988 • 7,590 citations

The nuclear receptor superfamily: The second decade

1995 • 6,929 citations

Recombinant Genomes Which Express Chloramphenicol Acetyltransferase in Mammalian Cells

1982 • 3,106 citations

Serial passaging and differentiation of myogenic cells isolated from dystrophic mouse muscle

1977 • 2,070 citations

Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor

1995 • 2,059 citations

A transcriptional co-repressor that interacts with nuclear hormone receptors

1995 • 1,744 citations

GAL4-VP16 is an unusually potent transcriptional activator

1988 • 1,379 citations

Crystal structure of the ligand-binding domain of the human nuclear receptor RXR-α

1995 • 1,179 citations

Crystal structure of the RAR-γ ligand-binding domain bound to all-trans retinoic acid

1995 • 1,085 citations

Determinants of target gene specificity for steroid/thyroid hormone receptors

1989 • 954 citations

A structural role for hormone in the thyroid hormone receptor

1995 • 938 citations

Transcription activation by the adenovirus E1a protein

1989 • 667 citations

Evolution of the nuclear receptor gene superfamily.

1992 • 662 citations

Protein encoded by v-erbA functions as a thyroid-hormone receptor antagonist

1989 • 599 citations

Polarity-specific activities of retinoic acid receptors determined by a co-repressor

1995 • 569 citations

Modular structure of a chicken lysozyme silencer: Involvement of an unusual thyroid hormone receptor binding site

1990 • 487 citations

An amino-terminal c-myc domain required for neoplastic transformation activates transcription.

1990 • 413 citations

A novel member of the thyroid/steroid hormone receptor family is encoded by the opposite strand of the rat c-erbA alpha transcriptional unit.

1989 • 316 citations

A Myogenic Cell Line with Altered Serum Requirements for Differentiation

1977 • 305 citations

A transferable silencing domain is present in the thyroid hormone receptor, in the v-erbA oncogene product and in the retinoic acid receptor.

1992 • 302 citations

An amino-terminal fragment of GAL4 binds DNA as a dimer

1989 • 296 citations

Two erbA homologs encoding proteins with different T3 binding capacities are transcribed from opposite DNA strands of the same genetic locus

1989 • 251 citations

The Monomer-Binding Orphan Receptor Rev-Erb Represses Transcription as a Dimer on a Novel Direct Repeat

1995 • 204 citations

Induction of Rev-ErbA alpha, an orphan receptor encoded on the opposite strand of the alpha-thyroid hormone receptor gene, during adipocyte differentiation

1993 • 199 citations

The Orphan Receptor Rev-ErbAα Activates Transcription via a Novel Response element

1993 • 199 citations

Cross-talk among ROR alpha 1 and the Rev-erb family of orphan nuclear receptors.

1994 • 194 citations

The Vitamin D Receptor Interacts with General Transcription Factor IIB

1995 • 166 citations

Transcriptional Activators Differ in Their Responses to Overexpression of TATA-Box-Binding Protein

1995 • 163 citations

An Amino-Terminal c-Myc Domain Required for Neoplastic Transformation Activates Transcription

1990 • 153 citations

Unliganded Thyroid Hormone Receptor α Can Target TATA-Binding Protein for Transcriptional Repression

1996 • 123 citations

A functional Rev-erb alpha responsive element located in the human Rev-erb alpha promoter mediates a repressing activity.

1996 • 121 citations

A new orphan member of the nuclear hormone receptor superfamily closely related to Rev-Erb.

1994 • 116 citations

Functional Evidence for Ligand-Dependent Dissociation of Thyroid Hormone and Retinoic Acid Receptors from an Inhibitory Cellular Factor

1994 • 116 citations

Identification of RVR, a novel orphan nuclear receptor that acts as a negative transcriptional regulator.

1994 • 109 citations

Constitutive expression of the orphan receptor, Rev-erbA alpha, inhibits muscle differentiation and abrogates the expression of the myoD gene family.

1995 • 93 citations

Thyroid Hormone Receptor Mutations that Interfere with Transcriptional Activation also Interfere with Receptor Interaction with a Nuclear Protein

1991 • 93 citations

Identification of a thyroid hormone response element in the mouse myogenin gene: characterization of the thyroid hormone and retinoid X receptor heterodimeric binding site.

1993 • 61 citations

Rev-erb beta, a new member of the nuclear receptor superfamily, is expressed in the nervous system during chicken development.

1994 • 54 citations

Thyroid hormone receptor dimerization function maps to a conserved subregion of the ligand binding domain.

1992 • 37 citations

Characterization of the thyroid hormone response element in the skeletal alpha-actin gene: negative regulation of T3 receptor binding by the retinoid X receptor.

1993 • 36 citations

Genetic dissection of thyroid hormone receptor β: identification of mutations that separate hormone binding and transcriptional activation

1995 • 34 citations