Structural and functional characterization of Sec66p, a new subunit of the polypeptide translocation apparatus in the yeast endoplasmic reticulum.

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

A simple method for displaying the hydropathic character of a protein

1982 • 22,471 citations

Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product.

1985 • 2,456 citations

70K heat shock related proteins stimulate protein translocation into microsomes

1988 • 1,276 citations

The signal peptide

1990 • 1,096 citations

Isolation of Monoclonal Antibodies Specific for Human c-myc Proto-Oncogene Product

1985 • 788 citations

KAR2, a karyogamy gene, is the yeast homolog of the mammalian BiP/GRP78 gene

1989 • 684 citations

Early stages in the yeast secretory pathway are required for transport of carboxypeptidase Y to the vacuole

1982 • 579 citations

Loss of BiP/GRP78 function blocks translocation of secretory proteins in yeast.

1990 • 435 citations

S. cerevisiae encodes an essential protein homologous in sequence and function to mammalian BiP

1989 • 421 citations

A yeast mutant defective at an early stage in import of secretory protein precursors into the endoplasmic reticulum.

1987 • 418 citations

Yeast Saccharomyces cerevisiae selectable markers in pUC18 polylinkers

1990 • 376 citations

Assembly of yeast Sec proteins involved in translocation into the endoplasmic reticulum into a membrane-bound multisubunit complex

1991 • 359 citations

Protein translocation mutants defective in the insertion of integral membrane proteins into the endoplasmic reticulum.

1992 • 352 citations

Multiple genes are required for proper insertion of secretory proteins into the endoplasmic reticulum in yeast.

1989 • 339 citations

A protein of the endoplasmic reticulum involved early in polypeptide translocation

1992 • 322 citations

The signal recognition particle in S. cerevisiae

1991 • 299 citations

A yeast gene important for protein assembly into the endoplasmic reticulum and the nucleus has homology to DnaJ, an Escherichia coli heat shock protein.

1989 • 296 citations

Nucleotide sequence and transcriptional mapping of the yeastpet56-his3-dedlgene region

1985 • 290 citations

YDJ1p facilitates polypeptide translocation across different intracellular membranes by a conserved mechanism

1992 • 280 citations

Topology and functional domains of Sec63p, an endoplasmic reticulum membrane protein required for secretory protein translocation.

1992 • 239 citations

SEC62 encodes a putative membrane protein required for protein translocation into the yeast endoplasmic reticulum.

1989 • 186 citations

GENETIC ANALYSIS OF THE YEAST CYTOSKELETON

1987 • 179 citations

Reconstitution of protein translocation from solubilized yeast membranes reveals topologically distinct roles for BiP and cytosolic Hsc70.

1993 • 171 citations

Invertase signal and mature sequence substitutions that delay intercompartmental transport of active enzyme.

1985 • 167 citations

Biosynthesis of the Vacuolar Yeast Glycoprotein Carboxypeptidase Y

1978 • 164 citations

Yeast Sec proteins interact with polypeptides traversing the endoplasmic reticulum membrane

1992 • 138 citations

Yeast Sec23p acts in the cytoplasm to promote protein transport from the endoplasmic reticulum to the Golgi complex in vivo and in vitro.

1989 • 128 citations

Saccharomyces cerevisiae and Schizosaccharomyces pombe contain a homologue to the 54-kD subunit of the signal recognition particle that in S. cerevisiae is essential for growth.

1989 • 115 citations

Signal recognition particle receptor is important for cell growth and protein secretion in Saccharomyces cerevisiae.

1992 • 109 citations

Primary sequence of the glucanase gene from Oerskovia xanthineolytica. Expression and purification of the enzyme from Escherichia coli.

1991 • 105 citations

The S. cerevisiae SEC65 gene encodes a component of yeast signal recognition particle with homology to human SRP19

1992 • 105 citations

Mutants in three novel complementation groups inhibit membrane protein insertion into and soluble protein translocation across the endoplasmic reticulum membrane of Saccharomyces cerevisiae.

1992 • 102 citations

Polypeptide translocation across the endoplasmic reticulum membrane.

1992 • 95 citations

Protein targeting to and translocation across the membrane of the endoplasmic reticulum

1992 • 66 citations

Enzymology of the pre-priming steps in lambda dv DNA replication in vitro.

1987 • 27 citations