Vasodilation to Bradykinin Is Mediated by an Ouabain-Sensitive Pathway as a Compensatory Mechanism for Impaired Nitric Oxide Availability in Essential Hypertensive Patients

Nitric oxide: physiology, pathophysiology, and pharmacology.

1991 • 15,563 citations

The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine

1980 • 12,033 citations

Abnormal Endothelium-Dependent Vascular Relaxation in Patients with Essential Hypertension

1990 • 2,388 citations

Ascorbate is an outstanding antioxidant in human blood plasma.

1989 • 1,876 citations

EFFECTS OF ENDOTHELIUM-DERIVED NITRIC OXIDE ON PERIPHERAL ARTERIOLAR TONE IN MAN

1989 • 1,625 citations

The measurement of volume changes in human limbs

1953 • 1,503 citations

Hyperpolarizing Vasodilators Activate ATP-sensitive K ⁺ Channels in Arterial Smooth Muscle

1989 • 1,197 citations

Coronary vasomotor response to acetylcholine relates to risk factors for coronary artery disease.

1990 • 1,190 citations

K+ is an endothelium-derived hyperpolarizing factor in rat arteries

1998 • 1,051 citations

Elevation of serum angiotension-converting-enzyme (ACE) level in sarcoidosis

1975 • 865 citations

A specific inhibitor of nitric oxide formation from <scp>l</scp>‐arginine attenuates endothelium‐dependent relaxation

1989 • 862 citations

Indirect evidence for release of endothelium-derived relaxing factor in human forearm circulation in vivo. Blunted response in essential hypertension.

1990 • 803 citations

Endothelium‐dependent hyperpolarization of canine coronary smooth muscle

1988 • 785 citations

Vitamin C Improves Endothelium-Dependent Vasodilation by Restoring Nitric Oxide Activity in Essential Hypertension

1998 • 771 citations

Vasodilation to acetylcholine in primary and secondary forms of human hypertension.

1993 • 550 citations

The Endothelium: Modulator of Cardiovascular Function

2020 • 543 citations

Endothelium-Dependent Hyperpolarization

1995 • 523 citations

Nitric Oxide Attenuates the Release of Endothelium-Derived Hyperpolarizing Factor

1996 • 433 citations

Impaired Endothelium-Dependent Vasodilation in Patients With Essential Hypertension

1995 • 430 citations

Sodium nitroprusside and other smooth muscle-relaxants increase cyclic GMP levels in rat ductus deferens

1977 • 422 citations

Vitamin C Improves Endothelial Dysfunction of Epicardial Coronary Arteries in Hypertensive Patients

1997 • 288 citations

Endothelium-dependent hyperpolarization caused by bradykinin in human coronary arteries.

1993 • 233 citations

Cyclooxygenase Inhibition Restores Nitric Oxide Activity in Essential Hypertension

1997 • 210 citations

Effect of Insulin on Acetylcholine-Induced Vasodilation in Normotensive Subjects and Patients With Essential Hypertension

1995 • 193 citations

Effects of angiotensin converting enzyme inhibition on endothelium-dependent vasodilatation in essential hypertensive patients

1998 • 109 citations

Two mechanisms mediate relaxation by bradykinin of pig coronary artery: NO-dependent and -independent responses

1991 • 97 citations

Why are converting enzyme inhibitors vasodilators?

1989 • 93 citations

Bradykinin-Induced Vasodilation Is Impaired at the Atherosclerotic Site but Is Preserved at the Spastic Site of Human Coronary Arteries In Vivo

1995 • 80 citations

Acetylcholine-induced vasodilatation in rabbit hindlimb in vivo is not inhibited by analogues of L-arginine

1991 • 76 citations

Measurement of plasma renin activity by angiotensin I radioimmunoassay: (I) an assessment of some methodological aspects.

1972 • 46 citations

Energy-transducing ATPases--structure and kinetics

1986 • 25 citations

Quasi-simultaneous measurement of ionized calcium and alpha-granule release in individual platelets

1991 • 24 citations

Fraud claims shake German complacency

1997 • 9 citations