Recent concepts in non‐alcoholic fatty liver disease

Prevalence of hepatic steatosis in an urban population in the United States: Impact of ethnicity

2004 • 3,594 citations

Nonalcoholic fatty liver disease: A spectrum of clinical and pathological severity☆, ☆☆

1999 • 3,339 citations

Nonalcoholic fatty liver, steatohepatitis, and the metabolic syndrome

2003 • 2,629 citations

Nonalcoholic steatohepatitis: Summary of an AASLD Single Topic Conference

2003 • 2,157 citations

The utility of radiological imaging in nonalcoholic fatty liver disease

2002 • 2,037 citations

Molecular mediators of hepatic steatosis and liver injury

2004 • 1,709 citations

Independent predictors of liver fibrosis in patients with nonalcoholic steatohepatitis

1999 • 1,610 citations

Magnetic resonance spectroscopy to measure hepatic triglyceride content: prevalence of hepatic steatosis in the general population

2004 • 1,502 citations

Mechanism of Hepatic Insulin Resistance in Non-alcoholic Fatty Liver Disease

2004 • 1,276 citations

Prevalence of and Risk Factors for Hepatic Steatosis in Northern Italy

2000 • 1,273 citations

Clinical and histologic spectrum of nonalcoholic fatty liver disease associated with normal ALT values

2003 • 1,171 citations

Cryptogenic cirrhosis: Clinical characterization and risk factors for underlying disease

1999 • 1,148 citations

Hepatocyte apoptosis and fas expression are prominent features of human nonalcoholic steatohepatitis

2003 • 1,033 citations

Beyond insulin resistance in NASH: TNF-? or adiponectin?

2004 • 934 citations

The histological course of nonalcoholic fatty liver disease: a longitudinal study of 103 patients with sequential liver biopsies

2004 • 916 citations

The natural history of nonalcoholic fatty liver: A follow-up study

1995 • 898 citations

The role of small intestinal bacterial overgrowth, intestinal permeability, endotoxaemia, and tumour necrosis factor alpha in the pathogenesis of non-alcoholic steatohepatitis

2001 • 820 citations

Free fatty acids promote hepatic lipotoxicity by stimulating TNF-α expression via a lysosomal pathway

2004 • 787 citations

Nonalcoholic steatohepatitis, insulin resistance, and metabolic syndrome: Further evidence for an etiologic association

2002 • 760 citations

Does central obesity reflect “Cushing's disease of the omentum”?

1997 • 755 citations

A pilot study of pioglitazone treatment for nonalcoholic steatohepatitis

2004 • 729 citations

Nonalcoholic fatty liver disease: Improvement in liver histological analysis with weight loss

2004 • 725 citations

Improved nonalcoholic steatohepatitis after 48 weeks of treatment with the PPAR-γ ligand rosiglitazone

2003 • 716 citations

Vitamin E and vitamin C treatment improves fibrosis in patients with nonalcoholic steatohepatitis

2003 • 704 citations

A Randomized Controlled Trial of Metformin versus Vitamin E or Prescriptive Diet in Nonalcoholic Fatty Liver Disease

2005 • 684 citations

NAFLD may be a common underlying liver disease in patients with hepatocellular carcinoma in the United States

2002 • 595 citations

Long term prognosis of fatty liver: risk of chronic liver disease and death

2004 • 493 citations

Therapeutic efficacy of an angiotensin II receptor antagonist in patients with nonalcoholic steatohepatitis

2004 • 455 citations

Prevalence of non‐alcoholic fatty liver disease and its association with impaired glucose metabolism in Japanese adults

2005 • 446 citations

A pilot study of vitamin E versus vitamin E and pioglitazone for the treatment of nonalcoholic steatohepatitis

2004 • 438 citations

Nonalcoholic fatty liver disease in patients with type 2 diabetes

2004 • 434 citations

Prevalence of fatty liver in Japanese children and relationship to obesity

1995 • 413 citations

Obesity and hepatocellular carcinoma

2004 • 393 citations

NAFLD may be a common underlying liver disease in patients with hepatocellular Carcinoma in the United States

2002 • 389 citations

Liver involvement in obese children. Ultrasonography and liver enzyme levels at diagnosis and during follow-up in an Italian population.

1997 • 384 citations

Improved nonalcoholic steatohepatitis after 48 weeks of treatment with the PPAR-γ ligand rosiglitazone

2003 • 359 citations

Apolipoprotein synthesis in nonalcoholic steatohepatitis

2002 • 327 citations

Tumor necrosis factor α promoter polymorphisms and insulin resistance in nonalcoholic fatty liver disease

2002 • 293 citations

Insulin effects on sterol regulatory-element-binding protein-1c (SREBP-1c) transcriptional activity in rat hepatocytes

2000 • 256 citations

Nonalcoholic fatty liver disease among patients with hypothalamic and pituitary dysfunction

2004 • 244 citations

Is Liver Biopsy Useful in the Evaluation of Patients with Chronically Elevated Liver Enzymes?

1989 • 217 citations

Chronological development of elevated aminotransferases in a nonalcoholic population

2004 • 201 citations

Hepatic microvascular dysfunction during evolution of dietary steatohepatitis in mice

2004 • 199 citations

The Prevalence of Autoantibodies and Autoimmune Hepatitis in Patients with Nonalcoholic Fatty Liver Disease

2004 • 198 citations

Hepatocyte CYP2E1 Overexpression and Steatohepatitis Lead to Impaired Hepatic Insulin Signaling

2005 • 194 citations

Inhibition of microsomal triglyceride transfer protein: Another mechanism for drug-induced steatosis in mice

2003 • 181 citations

The natural history of nonalcoholic fatty liver: A follow-up study

1995 • 156 citations

Prognosis of patients with a diagnosis of fatty liver--a registry-based cohort study.

2003 • 151 citations

The metabolic abnormalities associated with non-alcoholic fatty liver disease

2002 • 137 citations

Serum γ‐glutamyltransferase within its normal concentration range is related to the presence of diabetes and cardiovascular risk factors

2005 • 97 citations

Contribution of metabolic factors to alanine aminotransferase activity in persons with other causes of liver disease

2005 • 79 citations

Diagnosis of fatty liver disease

2003 • 68 citations

Current best treatment for non-alcoholic fatty liver disease

2003 • 46 citations

Relationship of non‐alcoholic hepatic steatosis to cortisol secretion in diet‐controlled Type 2 diabetic patients

2005 • 25 citations