Diacylglycerols and mezerein activate neutrophils by a phorbol myristate acetate‐like mechanism

Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters.

1982 • 4,786 citations

Activation of calcium and phospholipid-dependent protein kinase by diacylglycerol, its possible relation to phosphatidylinositol turnover.

1980 • 1,317 citations

Phorbol diester receptor copurifies with protein kinase C.

1983 • 1,185 citations

Human promyelocytic leukemia cells in culture differentiate into macrophage-like cells when treated with a phorbol diester.

1979 • 1,019 citations

Diacylglycerol and phorbol ester stimulate secretion without raising cytoplasmic free calcium in human platelets

1983 • 589 citations

Synergistic functions of phorbol ester and calcium in serotonin release from human platelets

1983 • 335 citations

Stimulation of neutrophil oxidative metabolism by chemotactic peptides: influence of calcium ion concentration and cytochalasin B and comparison with stimulation by phorbol myristate acetate

1979 • 259 citations

Granulocytes mediate acute edematous lung injury in rabbits and in isolated rabbit lungs perfused with phorbol myristate acetate: role of oxygen radicals.

1982 • 257 citations

The influence of phorbol myristate acetate on oxygen consumption by polymorphonuclear leukocytes.

1974 • 230 citations

Effect of phorbol 12-myristate 13-acetate and its analogue 4 alpha-phorbol 12,13-didecanoate on protein phosphorylation and lysosomal enzyme release in rabbit neutrophils.

1984 • 221 citations

Platelet activating factor. Stimulation of the lipoxygenase pathway in polymorphonuclear leukocytes by 1-O-alkyl-2-O-acetyl-sn-glycero-3-phosphocholine.

1982 • 194 citations

Biochemistry of the acute allergic reactions

1969 • 190 citations

Diacylglycerol, 1-oleoyl-2-acetyl-glycerol, stimulates superoxide-generation from human neutrophils

1984 • 189 citations

Specific degranulation of human polymorphonuclear leukocytes

1974 • 162 citations

Selective acylation of lyso platelet activating factor by arachidonate in human neutrophils.

1983 • 148 citations

Lymphocyte Activation by the Tumor-Promoting Agent 12-O-Tetradecanoylphorbol-13-Acetate (TPA)

1979 • 145 citations

Endogenous protein phosphorylation by resting and activated human neutrophils

1983 • 143 citations

Activation of protein kinase C by non-phorbol tumor promoter, mezerein

1984 • 135 citations

Surface‐reactive stimuli selectively increase protein phosphorylation in human neutrophils

1981 • 134 citations

Receptor-mediated regulation of superoxide production in human neutrophils stimulated by phorbol myristate acetate.

1981 • 121 citations

THE TUMOR-PROMOTER PHORBOL ESTER (12-0-TETRADECANOYL-PHORBOL-13-ACETATE), A POTENT AGGREGATING AGENT FOR BLOOD PLATELETS

1974 • 113 citations

Arachidonic acid induced degranulation of rabbit peritoneal neutrophils

1979 • 97 citations

Role of Ca2+ in phosphatidylinositol response and arachidonic acid release in formylated tripeptide- or Ca2+ ionophore A23187-stimulated guinea pig neutrophils.

1983 • 96 citations

Endogenous phospholipid metabolism in stimulated neutrophils differential activation by FMLP and PMA

1982 • 83 citations

Relation of human neutrophil phorbol ester receptor occupancy and NADPH- oxidase activity

1982 • 69 citations

Phorbol myristate acetate: in vivo effects upon neutrophils, platelets, and lung.

1980 • 67 citations

Selective desensitization of neutrophils: further studies with 1-O-alkyl-sn-glycero-3-phosphocholine analogues.

1981 • 64 citations

Neutrophil degranulation: Evidence pertaining to its mediation by the combined effects of leukotriene B₄, platelet‐activating factor, and 5‐HETE

1985 • 62 citations

Evidence for 5,12-dihydroxy-6,8,10,14-eicosatetraenoate as a mediator of human neutrophil aggregation

1981 • 57 citations

Diacylglycerols enhance human neutrophil degranulation responses: Relevancy to a multiple mediator hypothesis of cell function

1984 • 53 citations

Platelet-activating factor and analogues: comparative studies with human neutrophils and rabbit platelets.

1983 • 39 citations

PHORBOL ESTER RECEPTORS AND THE IN VITRO EFFECTS OF TUMOR PROMOTERS

1983 • 36 citations

Neutrophil Aggregation: Evidence for a Different Mechanism of Action by Phorbol Myristate Acetate

1980 • 36 citations

Histopathologic features of phorbol myristate acetate-induced lung injury.

1985 • 35 citations

Cytochalasin B-dependent release of azurophil granule enzymes from human polymorphonuclear leukocytes

1977 • 18 citations