Sp1-dependent activation of a synthetic promoter by human immunodeficiency virus type 1 Tat protein.

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

Transcriptional Regulation in Mammalian Cells by Sequence-Specific DNA Binding Proteins

1989 • 3,219 citations

Recombinant Genomes Which Express Chloramphenicol Acetyltransferase in Mammalian Cells

1982 • 3,106 citations

An inducible transcription factor activates expression of human immunodeficiency virus in T cells

1987 • 2,149 citations

Inducibility of κ immunoglobulin enhancer-binding protein NF-κB by a posttranslational mechanism

1986 • 2,043 citations

How eukaryotic transcriptional activators work

1988 • 1,924 citations

GAL4-VP16 is an unusually potent transcriptional activator

1988 • 1,379 citations

Affinity purification of sequence-specific DNA binding proteins.

1986 • 1,255 citations

Mechanism of transcriptional activation by Sp1: Evidence for coactivators

1990 • 1,029 citations

Deletion analysis of GAL4 defines two transcriptional activating segments

1987 • 898 citations

Trans -Activator Gene of Human T-Lymphotropic Virus Type III (HTLV-III)

1985 • 872 citations

The location of cis-acting regulatory sequences in the human T cell lymphotropic virus type III (HTLV-III/LAV) long terminal repeat

1985 • 825 citations

Activation of the AIDS Retrovirus Promoter by the Cellular Transcription Factor, Sp1

1986 • 741 citations

Regulation of mRNA accumulation by a human immunodeficiency virus trans-activator protein

1987 • 672 citations

Transcription activation by the adenovirus E1a protein

1989 • 667 citations

Tat trans-activates the human immunodeficiency virus through a nascent RNA target

1989 • 644 citations

The trans-activator gene of HTLV-III is essential for virus replication

1986 • 635 citations

The trans-activator gene of the human T cell lymphotropic virus type III is required for replication

1986 • 615 citations

Activators and targets

1990 • 582 citations

HIV-1 Tat protein increases transcriptional initiation and stabilizes elongation

1989 • 577 citations

A vector for expressing GAL4(1–147) fusions tn mammalian cells

1989 • 558 citations

HIV-1 tat trans-activation requires the loop sequence within tar

1988 • 551 citations

Human immunodeficiency virus 1 tat protein binds trans-activation-responsive region (TAR) RNA in vitro.

1989 • 472 citations

Tat Protein from Human Immunodeficiency Virus Forms a Metal-Linked Dimer

1988 • 464 citations

Fragments of the HIV-1 Tat Protein Specifically Biand TAR RNA

1990 • 446 citations

Structural and functional characterization of human immunodeficiency virus tat protein

1989 • 444 citations

A bulge structure in HIV-1 TAR RNA is required for Tat binding and Tat-mediated trans-activation.

1990 • 412 citations

HIV-1 tat protein stimulates transcription by binding to a U-rich bulge in the stem of the TAR RNA structure.

1990 • 400 citations

The yeast UASG is a transcriptional enhancer in human hela cells in the presence of the GAL4 trans-activator

1988 • 362 citations

A Transcriptional Activator Protein Encoded by the x- lor Region of the Human T-Cell Leukemia Virus

1985 • 346 citations

Elevated levels of mRNA can account for the trans-activation of human immunodeficiency virus.

1986 • 303 citations

HIV-1 Tat protein trans-activates transcription in vitro

1990 • 277 citations

Human immunodeficiency virus type 1 LTR TATA and TAR region sequences required for transcriptional regulation.

1989 • 275 citations

TAR-independent activation of the HIV-1 LTR: Evidence that Tat requires specific regions of the promoter

1990 • 253 citations

Multiple functional domains of Tat, thetrans-activator of HIV-1, defined by mutational analysis

1989 • 251 citations

Trans-activation of human immunodeficiency virus gene expression is mediated by nuclear events.

1987 • 246 citations

Trans-activation by HIV-1 Tat via a heterologous RNA binding protein

1990 • 236 citations

Transcription elongation and eukaryotic gene regulation.

1990 • 227 citations

The HIV-1 Tat protein: An RNA sequence-specific processivity factor?

1990 • 220 citations

Purification of the human immunodeficiency virus type 1 enhancer and TAR binding proteins EBP-1 and UBP-1.

1988 • 201 citations

Functional domains required for tat-induced transcriptional activation of the HIV-1 long terminal repeat.

1988 • 193 citations

Activation of transcription by HIV-1 Tat protein tethered to nascent RNA through another protein

1990 • 192 citations

Sequence-specific interaction of Tat protein and Tat peptides with the transactivation-responsive sequence element of human immunodeficiency virus type 1 in vitro.

1990 • 176 citations

HIV TAR: An RNA enhancer?

1989 • 175 citations

Synergy between HIV-1 Tat and adenovirus E1A is principally due to stabilization of transcriptional elongation.

1990 • 114 citations

Mutational analysis of the conserved cysteine-rich region of the human immunodeficiency virus type 1 Tat protein

1990 • 102 citations

The acidic amino-terminal region of the HIV-1 Tat protein constitutes an essential activating domain.

1989 • 68 citations

HIV trans-activation and transcription control mechanisms.

1989 • 52 citations

Does the human immunodeficiency virus tat trans-activator contain a discrete activation domain?

1990 • 42 citations

Interaction of enhancer-binding protein EBP1 (NF-kappa B) with the human immunodeficiency virus type 1 enhancer

1990 • 40 citations

Modulation of HIV-enhancer activity by heterologous agents: a minireview

1991 • 26 citations

Mapping of HIV-1 Tat protein sequences required for binding to Tar RNA

1991 • 25 citations