Genetic Restriction of AIDS Pathogenesis by an SDF-1 Chemokine Gene Variant

Regression Models and Life-Tables

1972 • 27,145 citations

A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation

1986 • 4,200 citations

HIV-1 Entry Cofactor: Functional cDNA Cloning of a Seven-Transmembrane, G Protein-Coupled Receptor

1996 • 4,184 citations

Identification of a major co-receptor for primary isolates of HIV-1

1996 • 3,649 citations

Rapid and sensitive detection of point mutations and DNA polymorphisms using the polymerase chain reaction

1989 • 3,557 citations

Homozygous Defect in HIV-1 Coreceptor Accounts for Resistance of Some Multiply-Exposed Individuals to HIV-1 Infection

1996 • 3,106 citations

Resistance to HIV-1 infection in Caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene

1996 • 2,883 citations

CC CKR5: A RANTES, MIP-1α, MIP-1β Receptor as a Fusion Cofactor for Macrophage-Tropic HIV-1

1996 • 2,735 citations

Genetic Restriction of HIV-1 Infection and Progression to AIDS by a Deletion Allele of the CKR5 Structural Gene

1996 • 2,502 citations

The lymphocyte chemoattractant SDF-1 is a ligand for LESTR/fusin and blocks HIV-1 entry

1996 • 1,973 citations

A highly efficacious lymphocyte chemoattractant, stromal cell-derived factor 1 (SDF-1)

1996 • 1,482 citations

Change in Coreceptor Use Correlates with Disease Progression in HIV-1–Infected Individuals

1997 • 1,373 citations

The role of a mutant CCR5 allele in HIV–1 transmission and disease progression

1996 • 1,364 citations

Genotypic and Phenotypic Characterization of HIV-1 Patients with Primary Infection

1993 • 1,258 citations

THE MULTICENTER AIDS COHORT STUDY: RATIONALE, ORGANIZATION, AND SELECTED CHARACTERISTICS OF THE PARTICIPANTS

1987 • 1,150 citations

Host factors and the pathogenesis of HIV-induced disease

1996 • 857 citations

Signal Sequence Trap: a Cloning Strategy for Secreted Proteins and Type I Membrane Proteins

1993 • 722 citations

Relative resistance to HIV–1 infection of CD4 lymphocytes from persons who remain uninfected despite multiple high–risk sexual exposures

1996 • 656 citations

Structure and Chromosomal Localization of the Human Stromal Cell-Derived Factor 1 (SDF1) Gene

1995 • 629 citations

A Prospective Study of Human Immunodeficiency Virus Type 1 Infection and the Development of AIDS in Subjects with Hemophilia

1989 • 536 citations

REPLICATIVE CAPACITY OF HUMAN IMMUNODEFICIENCY VIRUS FROM PATIENTS WITH VARYING SEVERITY OF HIV INFECTION

1986 • 536 citations

Increased viral burden and cytopathicity correlate temporally with CD4+ T-lymphocyte decline and clinical progression in human immunodeficiency virus type 1-infected individuals

1993 • 464 citations

The role of viral phenotype and CCR-5 gene defects in HIV-1 transmission and disease progression

1997 • 454 citations

Inherited Resistance to HIV-1 Conferred by an Inactivating Mutation in CC Chemokine Receptor 5: Studies in Populations with Contrasting Clinical Phenotypes, Defined Racial Background, and Quantified Risk

1997 • 423 citations

Long-term HIV-1 infection without immunologic progression

1994 • 382 citations

Detecting single base substitutions as heteroduplex polymorphisms

1992 • 365 citations

Monocytotropic human immunodeficiency virus type 1 (HIV-1) variants detectable in all stages of HIV-1 infection lack T-cell line tropism and syncytium-inducing ability in primary T-cell culture

1991 • 326 citations

Control of messenger RNA stability in higher eukaryotes

1996 • 315 citations

Chemokines and HIV–1 second receptors

1996 • 304 citations

Viral Phenotype and Immune Response in Primary Human Immunodeficiency Virus Type 1 Infection

1992 • 268 citations

A Model-Based Estimate of the Mean Incubation Period for AIDS in Homosexual Men

1988 • 240 citations

Isolation of the Human Interleukin 10 Promoter. Characterization of the Promoter Activity in Burkitt's Lymphoma Cell Lines

1995 • 221 citations

Sensitivity of single-strand conformation polymorphism and heteroduplex method for mutation detection in the cystic fibrosis gene

1994 • 190 citations

Hemophilia Growth and Development Study

1993 • 125 citations

Host Genes and HIV: The Role of the Chemokine Receptor Gene CCR5 and Its Allele (∆32 CCR5)

1997 • 103 citations

Post-Transcriptional Regulation of the GAP-43 Gene by Specific Sequences in the 3′ Untranslated Region of the mRNA

1997 • 67 citations

HIV Receptors and the Pathogenesis of AIDS

1996 • 64 citations

Tumor Necrosis Factor-α Regulation of Glucose Transporter (GLUT1) mRNA Turnover

1997 • 51 citations

Human Immunodeficiency Virus (HIV) Type 1 Infection Status and In Vitro Susceptibility to HIV Infection among High-Risk HIV-I-Seronegative Hemophiliacs

1995 • 18 citations