Characteristics of Tryptophan Accumulation by Isolated Rat Forebrain Synaptosomes

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

The isolation of nerve endings from brain: an electron-microscopic study of cell fragments derived by homogenization and centrifugation.

1962 • 2,522 citations

Use of the liquid scintillation spectrometer for determining adenosine triphosphate by the luciferase enzyme

1969 • 898 citations

A rapid method for the preparation of relatively pure metabolically competent synaptosomes from rat brain

1978 • 464 citations

Partial Purification and Characterization of Tryptophan Hydroxylase from Rabbit Hindbrain

1972 • 445 citations

Error in the determination of tryptophan by the method of Denkla and Dewey. A revised procedure

1974 • 423 citations

Tryptophan hydroxylase inhibition: the mechanism by which p-chlorophenylalanine depletes rat brain serotonin.

1967 • 418 citations

Energy transduction in intact synaptosomes. Influence of plasma-membrane depolarization on the respiration and membrane potential of internal mitochondria determined in situ

1980 • 391 citations

KINETICS OF COMPETITIVE INHIBITION OF NEUTRAL AMINO ACID TRANSPORT ACROSS THE BLOOD‐BRAIN BARRIER

1977 • 357 citations

Biochemistry of tryptophan in health and disease

1983 • 329 citations

Effects of veratrum alkaloids on membrane potential and conductance of squid and crayfish giant axons.

1973 • 252 citations

Tryptophan-5-hydroxylase: function and control.

1974 • 237 citations

RESPIRATION IN VITRO OF SYNAPTOSOMES FROM MAMMALIAN CEREBRAL CORTEX

1969 • 181 citations

Relevance of free tryptophan in serum to tissue tryptophan concentrations

1974 • 161 citations

EFFECTS ON PLASMA AND BRAIN TRYPTOPHAN IN THE RAT OF DRUGS AND HORMONES THAT INFLUENCE THE CONCENTRATION OF UNESTERIFIED FATTY ACID IN THE PLASMA

1974 • 141 citations

Resolution of DL-Tryptophan by Affinity Chromatography on Bovine-Serum Albumin-Agarose Columns

1973 • 132 citations

The morphology of fractions of rat forebrain synaptosomes separated on continuous sucrose density gradients

1968 • 131 citations

TRYPTOPHAN TRANSPORT ACROSS THE SYNAPTOSOMAL MEMBRANE¹

1970 • 117 citations

In-vivo measurements of tryptophan and tyrosine hydroxylase activities in mouse brain

1973 • 111 citations

The influx of amino acids into the brain of the rat in vivo : the essential compared with some non-essential amino acids

1973 • 104 citations

The effect of L-tryptophan and some psychotropic drugs on the formation of 5-hydroxytryptophan in the mouse brain in vivo

1972 • 89 citations

Dietary Carbohydrate Increases Brain Tryptophan and Decreases Free Plasma Tryptophan

1973 • 89 citations

TRANSPORT OF <scp>l</scp>‐TRYPTOPHAN INTO SLICES OF RAT CEREBRAL CORTEX¹

1972 • 73 citations

The metabolism of L-tryptophan by isolated rat liver cells. Effect of albumin binding and amino acid competition on oxidatin of tryptophan by tryptophan 2,3-dioxygenase

1980 • 63 citations

Estimation of the Rate of Tryptophan Hydroxylation In Vivo: A Sensitive Microassay in Discrete Rat Brain Nuclei

1980 • 51 citations

TRANSPORT OF THREONINE AND TRYPTOPHAN BY RAT BRAIN SLICES: RELATION TO OTHER AMINO ACIDS AT CONCENTRATIONS FOUND IN PLASMA¹

1978 • 47 citations

REGIONAL TRANSPORT OF TRYPTOPHAN IN RAT BRAIN

1977 • 44 citations

MODIFIED TRANSPORT SUBSTRATES AS PROBES FOR INTRAMEMBRANE GRADIENTS*

1974 • 44 citations

Estimation of the rate of 5-HT synthesis in the mouse brain by varius methods

1974 • 44 citations

The relevance of both plasma free tryptophan and insulin to rat brain tryptophan concentration

1976 • 43 citations

THE CHLORIDE CONTENT, ANION DEFICIT AND VOLUME OF SYNAPTOSOMES

1975 • 41 citations

Possible role of insulin in the transport of tyrosine and tryptophan from blood to brain

1975 • 31 citations

Textbook of physiology and biochemistry

1973 • 30 citations

A method for the rapid separation of soluble and particulate components of rat brain synaptosomes

1979 • 29 citations

Effect of Age on Variables Influencing the Supply of Tryptophan to the Brain

1982 • 27 citations

A Sensitive Radiometric Assay for Tryptophan Hydroxylase Applicable to Crude Extracts

1983 • 26 citations

A microassay for simultaneous measurement of in vivo rates of tryptophan hydroxylation and levels of serotonin in discrete brain nuclei

1982 • 16 citations

Relationships between tryptophan concentrations in human plasma, cerebrospinal fluid and cerebral cortex following tryptophan infusion

1980 • 10 citations

Kinetics of tryptophan accumulation into synaptosomes of various regions of rat brain

1979 • 8 citations