Estimation of the Rate of Tryptophan Hydroxylation In Vivo: A Sensitive Microassay in Discrete Rat Brain Nuclei

Simultaneous measurement of tyrosine and tryptophan hydroxylase activities in brain in Vivo using an inhibitor of the aromatic amino acid decarboxylase

1972 • 649 citations

Tryptophan hydroxylase inhibition: the mechanism by which p-chlorophenylalanine depletes rat brain serotonin.

1967 • 418 citations

Serotonin content of the brain stem nuclei in the rat

1974 • 380 citations

A specific and sensitive enzymatic-isotopic microassay for serotonin in tissues.

1973 • 285 citations

Further studies on tryptophan hydroxylase in rat brainstem and beef pineal

1969 • 225 citations

Serotonin-containing neuronal perikarya and terminals: differential effects of p-chlorophenylalanine

1973 • 199 citations

Conjoint native and orthophthaldialdehyde-condensate assays for the fluorimetric determination of 5-hydroxyindoles in brain

1973 • 176 citations

In-vivo measurements of tryptophan and tyrosine hydroxylase activities in mouse brain

1973 • 111 citations

FEEDBACK REGULATION OF 5‐HT SYNTHESIS IN RAT STRIATAL SLICES

1973 • 89 citations

Regulation of serotonin synthesis

1974 • 86 citations

Quantitative Estimation of 5-Hydroxy-3-Indole Acetic Acid and 5-Hydroxytryptophan in the Brain Following Isolation by Means of a Strong Cation Exchange Column

1971 • 75 citations

Increase in tyrosine hydroxylase activity in the locus coeruleus of the rat brain after contralateral lesioning

1975 • 74 citations

The role of intraneuronal amine levels in the feedback control of dopamine, noradrenaline and 5-hydroxytryptamine synthesis in rat brain

1976 • 71 citations

Modulation of brain tryptophan hydroxylase activity by brain tryptophan content.

1977 • 66 citations

Measurement of 5HT turnover rate in discrete nuclei of rat brain

1976 • 62 citations

Tryptophan hydroxylase in the rat brain

1975 • 62 citations

Early increase in phenylethanolamine-N-methyltransferase activity in a new strain of spontaneously hypertensive rats

1978 • 47 citations

REGIONAL TRANSPORT OF TRYPTOPHAN IN RAT BRAIN

1977 • 44 citations

Estimation of the rate of 5-HT synthesis in the mouse brain by varius methods

1974 • 44 citations

The mechanism of inhibition of hydroxylases in vivo by : The effect of cycloheximide

1971 • 38 citations

A SENSITIVE MICROASSAY FOR TRYPTOPHAN HYDROXYLASE IN BRAIN

1975 • 33 citations

Tryptophan hydroxylase in discrete brain nuclei: Comparison of activity in vitro and in vivo

1976 • 32 citations

Measurement of tryptophan hydroxylase in single brain nuclei by high pressure liquid chromatography

1975 • 27 citations

Effects of halothane and nitrous oxide anaesthesia on 5-HT turn-over in the rat brain

1975 • 18 citations

Tryptophan-5-hydroxylase activity in the raphe system of the rat brain stem

1975 • 14 citations

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