Transdermal iontophoresis of the dopamine agonist 5-OH-DPAT in human skin in vitro

Percutaneous Penetration Enhancers

2005 • 368 citations

Clinical Pharmacokinetic and Pharmacodynamic Properties of Drugs Used in the Treatment of Parkinson??s Disease

2002 • 327 citations

Water Distribution and Related Morphology in Human Stratum Corneum at Different Hydration Levels

2003 • 306 citations

Multi-species assessment of electrical resistance as a skin integrity marker for in vitro percutaneous absorption studies

2004 • 223 citations

Characterization of the iontophoretic permselectivity properties of human and pig skin

2001 • 181 citations

Transdermal ion migration

1992 • 140 citations

Iontophoretic delivery across the skin: electroosmosis and its modulation by drug substances.

1997 • 83 citations

Synthesis and dopaminergic activity of (+-)-, (+)-, and (-)-2-dipropylamino-5-hydroxy-1,2,3,4-tetrahydronaphthalene

1976 • 82 citations

Iontophoretic enhancement of peptides: behaviour of leuprolide versus model permeants

1994 • 74 citations

Enhanced transdermal delivery of AZT (Zidovudine) using iontophoresis and penetration enhancer

1998 • 73 citations

Iontophoretic delivery of apomorphine. II: An in vivo study in patients with Parkinson's disease.

1997 • 63 citations

Synthesis and radioreceptor binding activity of N-0437, a new, extremely potent and selective D2 dopamine receptor agonist

1985 • 53 citations

Transdermal Iontophoresis of Rotigotine Across Human Stratum Corneum in Vitro: Influence of pH and NaCl Concentration

2004 • 53 citations

In vitro transdermal iontophoretic transport of timolol maleate: effect of age and species

2001 • 53 citations

Iontophoretic delivery of apomorphine. I: In vitro optimization and validation.

1997 • 52 citations

Efficacy, safety, and tolerability of pramipexole in untreated and levodopa-treated patients with Parkinson's disease

2003 • 51 citations

Iontophoretic delivery of ropinirole hydrochloride: effect of current density and vehicle formulation.

2001 • 48 citations

Iontophoresis of nafarelin: Effects of current density and concentration on electrotransport in vitro

1995 • 46 citations

Transdermal iontophoresis of rotigotine: influence of concentration, temperature and current density in human skin in vitro

2004 • 43 citations

N-0437:a selective D-2 dopamine receptor agonist in in vitro and in vivo models

1988 • 42 citations

N‐0923, A novel soluble dopamine D₂ agonist in the treatment of parkinsonism

1998 • 39 citations

Extensive gastrointestinal metabolic conversion limits the oral bioavailability of the dopamine D2 agonist N-0923 in freely moving rats.

1992 • 35 citations

Further characterization of structural requirements for agonists at the striatal dopamine D2 receptor and a comparison with those at the striatal dopamine D1 receptor. Studies with a series of monohydroxyaminotetralins on acetylcholine release from rat striatum.

1984 • 34 citations

In vitro iontophoresis of R-apomorphine across human stratum corneum

2002 • 31 citations

Dopamine agonists: the treatment for Parkinson's disease in the XXI century?

2000 • 26 citations

Validation and testing of a new iontophoretic continuous flow through transport cell

1998 • 23 citations

Lontophoretic delivery of apomorphine in vitro: physicochemic considerations.

2001 • 20 citations

Thiophene analogs of naphthoxazines and 2-aminotetralins: bioisosteres with improved relative oral bioavailability, as compared to 5-OH-DPAT

2000 • 19 citations

Effect of elastic liquid-state vesicle on apomorphine iontophoresis transport through human skin in vitro.

2001 • 16 citations

Pretreatment with a water-based surfactant formulation affects transdermal iontophoretic delivery of R-apomorphine in vitro.

2003 • 15 citations

Iontophoretic R-apomorphine delivery in combination with surfactant pretreatment: in vitro validation studies

2003 • 13 citations

Pharmacokinetics and disposition of the novel dopamine agonist Z-7760 in rat after intravenous and oral administration

2000 • 2 citations