The Muscle Regulatory Factors MyoD and Myf-5 Undergo Distinct Cell Cycle–specific Expression in Muscle Cells

Expression of a single transfected cDNA converts fibroblasts to myoblasts

1987 • 3,373 citations

Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals

1994 • 2,154 citations

Cyclins and cancer II: Cyclin D and CDK inhibitors come of age

1994 • 2,122 citations

Serial passaging and differentiation of myogenic cells isolated from dystrophic mouse muscle

1977 • 2,070 citations

A Method for Isolation of Intact, Translationally Active Ribonucleic Acid

1983 • 1,469 citations

The E2F transcription factor is a cellular target for the RB protein

1991 • 1,461 citations

Myogenin, a factor regulating myogenesis, has a domain homologous to MyoD

1989 • 1,286 citations

Correlation of Terminal Cell Cycle Arrest of Skeletal Muscle with Induction of p21 by MyoD

1995 • 1,154 citations

The MyoD family and myogenesis: Redundancy, networks, and thresholds

1993 • 1,062 citations

Inactivation of MyoD in mice leads to up-regulation of the myogenic HLH gene Myf-5 and results in apparently normal muscle development

1992 • 973 citations

Single-Cell Analysis of Regulatory Gene Expression in Quiescent and Activated Mouse Skeletal Muscle Satellite Cells

1997 • 918 citations

Cyclin a is required for the onset of DNA replication in mammalian fibroblasts

1991 • 884 citations

MyoD1: A Nuclear Phosphoprotein Requiring a Myc Homology Region to Convert Fibroblasts to Myoblasts

1988 • 839 citations

Interaction of myogenic factors and the retinoblastoma protein mediates muscle cell commitment and differentiation

1993 • 734 citations

Requirement of p27 ^Kip1 for Restriction Point Control of the Fibroblast Cell Cycle

1996 • 683 citations

Myogenin expression, cell cycle withdrawal, and phenotypic differentiation are temporally separable events that precede cell fusion upon myogenesis.

1996 • 601 citations

Ordering S phase and M phase in the cell cycle

1994 • 596 citations

Skeletal muscle satellite cells

1994 • 538 citations

Commitment, fusion and biochemical differentiation of a myogenic cell line in the absence of DNA synthesis

1978 • 491 citations

Growth factor control of skeletal muscle differentiation: commitment to terminal differentiation occurs in G1 phase and is repressed by fibroblast growth factor.

1987 • 480 citations

Temporal expression of regulatory and structural muscle proteins during myogenesis of satellite cells on isolated adult rat fibers

1994 • 442 citations

MyoD-Induced Expression of p21 Inhibits Cyclin-Dependent Kinase Activity upon Myocyte Terminal Differentiation

1995 • 416 citations

Inhibition of myogenic differentiation in proliferating myoblasts by cyclin D1-dependent kinase

1995 • 404 citations

The retinoblastoma protein pathway and the restriction point

1996 • 392 citations

Reversal of Terminal Differentiation Mediated by p107 in Rb ^-/- Muscle Cells

1994 • 369 citations

“Spontaneous” differentiation of skeletal myoblasts is dependent upon autocrine secretion of insulin-like growth factor-II

1991 • 365 citations

Muscle-specific transcriptional activation by MyoD.

1991 • 347 citations

What is the restriction point?

1995 • 345 citations

Regulation of the cell cycle by the cdk2 protein kinase in cultured human fibroblasts.

1993 • 325 citations

Cell cycle exit upon myogenic differentiation

1997 • 323 citations

A role for FGF-6 in skeletal muscle regeneration

1997 • 316 citations

Skeletal muscle cells lacking the retinoblastoma protein display defects in muscle gene expression and accumulate in S and G2 phases of the cell cycle.

1996 • 305 citations

Temporal expression of myogenic regulatory genes during activation, proliferation, and differentiation of rat skeletal muscle satellite cells

1994 • 278 citations

Cell proliferation inhibited by MyoD1 independently of myogenic differentiation

1990 • 224 citations

[7] Cell synchronization

1995 • 206 citations

MyoD induces growth arrest independent of differentiation in normal and transformed cells.

1990 • 203 citations

Cyclin A is required for the onset of DNA replication in mammalian fibroblasts

1992 • 185 citations

Microinjection of p34cdc2 kinase induces marked changes in cell shape, cytoskeletal organization, and chromatin structure in mammalian fibroblasts

1990 • 153 citations

Positive and Negative Regulation of D-type Cyclin Expression in Skeletal Myoblasts by Basic Fibroblast Growth Factor and Transforming Growth Factor β

1995 • 133 citations

RhoA GTPase and Serum Response Factor Control Selectively the Expression of MyoD without Affecting Myf5 in Mouse Myoblasts

1998 • 126 citations

Cell Cycle–regulated Expression of the Muscle Determination Factor Myf5 in Proliferating Myoblasts

1998 • 117 citations

Monoclonal antibodies to the myogenic regulatory protein MyoD1: epitope mapping and diagnostic utility.

1992 • 109 citations

Control of myogenesis in the mouse myogenic C2 cell line by medium composition and by insulin: Characterization of permissive and inducible C2 myoblasts

1988 • 94 citations

Inhibition of myogenic differentiation in myoblasts expressing a truncated type II TGF-β receptor

1994 • 86 citations

Acidic and basic Fibroblast Growth Factor mRNAs are expressed by skeletal muscle satellite cells

1990 • 78 citations

3,5,3'-Triiodothyronine positively regulates both MyoD1 gene transcription and terminal differentiation in C2 myoblasts.

1992 • 72 citations

Autonomous differentiation in the mouse myogenic cell line, C2, involves a mutual positive control between insulin-like growth factor II and MyoD, operating as early as at the myoblast stage

1996 • 60 citations

Serum-induced inhibition of myogenesis is differentially relieved by retinoic acid and triiodothyronine in C2 murine muscle cells

1993 • 59 citations

Myf5, MyoD, myogenin and MRF4 myogenic derivatives of the embryonic mesenchymal cell line C3H10T1/2 exhibit the same adult muscle phenotype

1994 • 53 citations

Manipulation of medium conditions and differentiation in the rat myogenic cell line L6

1984 • 43 citations

MyoD induced cell cycle arrest is associated with increased nuclear affinity of the Rb protein.

1993 • 38 citations

The glucocorticoid receptor and AP-1 are involved in a positive regulation of the muscle regulatory gene myf5 in cultured myoblasts

1997 • 20 citations

MyoD Functions as a Transcriptional Repressor in Proliferating Myoblasts

1997 • 15 citations