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MCL-1 expression in B-cell non-Hodgkin’s lymphomas

Data up to Jan 2025

Published2004
Citations97
References36

Total Citations Per Year

Abstract

References (36)

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2002 • 4,781 citations

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Serine Phosphorylation of Death Agonist BAD in Response to Survival Factor Results in Binding to 14-3-3 Not BCL-XL

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MCL1, a gene expressed in programmed myeloid cell differentiation, has sequence similarity to BCL2.

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Multiple Myeloma: Increasing Evidence for a Multistep Transformation Process

1998 • 761 citations

Expression of Apoptosis-Regulating Proteins in Chronic Lymphocytic Leukemia: Correlations With In Vitro and In Vivo Chemoresponses

1998 • 656 citations

Antisense strategy shows that Mcl-1 rather than Bcl-2 or Bcl-xL is an essential survival protein of human myeloma cells

2002 • 420 citations

Myeloid cell factor–1 is a critical survival factor for multiple myeloma

2002 • 365 citations

Mcl-1 Expression in Human Neutrophils: Regulation by Cytokines and Correlation With Cell Survival

1998 • 349 citations

Immunohistochemical analysis of Mcl-1 protein in human tissues. Differential regulation of Mcl-1 and Bcl-2 protein production suggests a unique role for Mcl-1 in control of programmed cell death in vivo.

1995 • 317 citations

Incidence, predictive factors, and outcome of lymphoma transformation in follicular lymphoma patients.

1997 • 310 citations

MCL-1S, a Splicing Variant of the Antiapoptotic BCL-2 Family Member MCL-1, Encodes a Proapoptotic Protein Possessing Only the BH3 Domain

2000 • 273 citations

MCL1 provides a window on the role of the BCL2 family in cell proliferation, differentiation and tumorigenesis

2002 • 265 citations

Apoptotic-Regulatory and Complement-Protecting Protein Expression in Chronic Lymphocytic Leukemia: Relationship to In Vivo Rituximab Resistance

2003 • 188 citations

MCL1 transgenic mice exhibit a high incidence of B-cell lymphoma manifested as a spectrum of histologic subtypes

2001 • 186 citations

Exon Skipping in Mcl-1 Results in a Bcl-2 Homology Domain 3 Only Gene Product That Promotes Cell Death

2000 • 184 citations

Mcl-1 in Transgenic Mice Promotes Survival in a Spectrum of Hematopoietic Cell Types and Immortalization in the Myeloid Lineage

1998 • 151 citations

Expression of the Bcl-2 homologue Mcl-1 correlates with survival of peripheral blood B lymphocytes.

1996 • 103 citations

Expression of Mcl‐1 in mantle cell lymphoma is associated with high‐grade morphology, a high proliferative state, and p53 overexpression

2002 • 98 citations

Immunoblot analysis of cellular expression of Bcl-2 family proteins, Bcl-2, Bax, Bcl-X and Mcl-1, in human peripheral blood and lymphoid tissues

1995 • 94 citations

Myeloid Cell Leukemia 1 Is Phosphorylated through Two Distinct Pathways, One Associated with Extracellular Signal-regulated Kinase Activation and the Other with G2/M Accumulation or Protein Phosphatase 1/2A Inhibition

2000 • 81 citations

BCL‐2 family proteins in peripheral T‐cell lymphomas: correlation with tumour apoptosis and proliferation

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Immunodetection of apoptosis-regulating proteins in lymphomas from patients with and without human immunodeficiency virus infection.

1996 • 52 citations

Bcl‐2 family of proteins in indolent B‐cell non‐Hodgkin's lymphoma: Study of 116 cases

2002 • 48 citations

Molecular heterogeneity of B-lineage diffuse large cell lymphoma

1996 • 42 citations

IL-6-independent expression of Mcl-1 in human multiple myeloma

2003 • 42 citations

Identification of chromosomal copy number changes associated with transformation of follicular lymphoma to diffuse large B-cell lymphoma

2003 • 31 citations

High-Grade Malignant Non-Hodgkin’s Lymphomas Differ from Low-Grade Lymphomasin the Extent of Apoptosis andTheir Expression of bcl-2, mcl-1,bax and p53

1998 • 29 citations

Apoptosis-Regulating Proteins and Prognosis in Diffuse Large B Cell Non-Hodgkin’s Lymphomas

2002 • 26 citations

The Prognostic Relevance of Apoptosis-related Proteins in Classical Hodgkin's Lymphomas

2003 • 25 citations

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Dysregulation of apoptosis in Waldenstrom's macroglobulinemia does not involve nuclear factor kappa B activation

2003 • 8 citations

Gene expression in human neutrophils

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