Pancreatic Response in Rats and Mice to Trypsin Inhibitors from Soy and Potato After Short- and Long-Term Dietary Exposure

Official Methods of Analysis of

1980 • 61,391 citations

Regression Models and Life-Tables

1992 • 27,454 citations

Regression Models and Life-Tables

1972 • 27,145 citations

Multiple Range and Multiple F Tests

1955 • 22,685 citations

Report of the American Institute of Nutrition Ad Hoc Committee on Standards for Nutritional Studies

1977 • 2,748 citations

Determination of trypsin inhibitor activity of soy products: a collaborative analysis of an improved procedure

1974 • 868 citations

Guidelines for simple, sensitive significance tests for carcinogenic effects in long-term animal experiments.

1980 • 465 citations

Feedback Regulation of Pancreatic Enzyme Secretion as a Mechanism for Trypsin Inhibitor-Induced Hypersecretion in Rats

1972 • 449 citations

Bioassay of plasma cholecystokinin in rats: Effects of food, trypsin inhibitor, and alcohol

1984 • 414 citations

Hormonal Control of Pancreatic Growth

1973 • 243 citations

Feedback regulation of pancreatic enzyme secretion. Suppression of cholecystokinin release by trypsin.

1986 • 223 citations

Cholecystokinin mediates feedback regulation of pancreatic enzyme secretion in rats

1986 • 193 citations

Role of cholecystokinin in the negative feedback control of pancreatic enzyme secretion in conscious rats

1987 • 168 citations

Endogenous CCK Release and Pancreatic Growth in Rats After Feeding a Proteinase Inhibitor (Carnostate)

1986 • 135 citations

The Effect of Raw Soybean Meal and Trypsin Inhibitor Diets on Pancreatic Enzyme Secretion in the Rat

1957 • 133 citations

The Effects of Long-Term Feeding of Soya Flour on the Rat Pancreas

1980 • 132 citations

Effect of Raw Soybean Meal and Amino Acids on Pancreatic Hypertrophy in Rats

1960 • 132 citations

Antinutrients and natural toxicants in foods

1981 • 129 citations

Factors Involved in the Intestinal Feedback Regulation of Pancreatic Enzyme Secretion in the Rat

1975 • 126 citations

Effect of a trypsin inhibitor from soybeans (Bowman-Birk) on the secretory activity of the human pancreas

1988 • 115 citations

A cholecystokinin releasing peptide mediates feedback regulation of pancreatic secretion

1989 • 113 citations

Purification and sequencing of a trypsin-sensitive cholecystokinin-releasing peptide from rat pancreatic juice. Its homology with pancreatic secretory trypsin inhibitor.

1987 • 102 citations

Effect of Soy Protein, Casein and Trypsin Inhibitor on Cholesterol, Bile Acids and Pancreatic Enzymes in Mice

1981 • 94 citations

Effects of L-364,718, a new cholecystokinin receptor antagonist, on camostate-induced growth of the rat pancreas

1988 • 94 citations

Gastrointestinal Hormones and their Functions

1977 • 92 citations

A Comparative Study of the Nutritional and Physiological Significance of Pure Soybean Trypsin Inhibitors and of Ethanol-extracted Soybean Meals in Chicks and Rats

1967 • 86 citations

Pancreatic growth: interaction of exogenous cholecystokinin, a protease inhibitor, and a cholecystokinin receptor antagonist in mice.

1987 • 79 citations

The influence of different nutrients on plasma cholecystokinin levels in the rat

1988 • 75 citations

Peptide YY inhibits pancreatic secretion by inhibiting cholecystokinin release in the dog

1988 • 74 citations

Nutritional and Metabolic Response to Plant Inhibitors of Digestive Enzymes

1984 • 70 citations

The Nutritive Quality and the Trypsin Inhibitor Content of Soybean Flour Heated at Various Temperatures

1948 • 69 citations

Growth Depression and Pancreatic and Intestinal Changes in Rats Force-fed Amino Acid Diets Containing Soybean Trypsin Inhibitor

1966 • 68 citations

Potentiation of the action of azaserine on the rat pancreas by raw soya bean flour

1977 • 64 citations

Two hypotheses on the feedback regulation of pancreatic enzyme secretion

1989 • 64 citations

The release of rat intestinal cholecystokinin after oral trypsin inhibitor measured by bio‐assay.

1981 • 62 citations

Effects of soybean flour on the pancreas of rats.

1984 • 59 citations

Plasma cholecystokinin and pancreatic growth during adaptation to dietary protein

1986 • 59 citations

Hypertrophy and Hyperplasia in the Endocrine and Exocrine Pancreas of Rats Fed Soybean Trypsin Inhibitor or Repeatedly Injected with Pancreozymin

1976 • 58 citations

Carcinogenic Effects of Di(2-hydroxypropyl)nitrosamine (DHPN) in Male Wistar Rats: Promotion of Pancreatic Cancer by a Raw Soya Flour Diet

1979 • 55 citations

Raw soya-bean flour increases cholecystokinin release in man

1987 • 45 citations

Nutritional and Toxicological Aspects of Food Safety

1984 • 42 citations

Role of gastrin and cholecystokinin in tumours of the gastrointestinal tract

1988 • 42 citations

The USDA trypsin inhibitor study. I. Background, objectives, and procedural details

1985 • 41 citations

Effect of Soybean Trypsin Inhibitor and Penicillin on Cystine Biosynthesis in the Pancreas and Its Transport as Exocrine Protein Secretion in the Intestinal Tract of the Rat

1965 • 41 citations

Stimulation of pancreatic secretory process in the rat by low-molecular weight proteinase inhibitor

1987 • 41 citations

Safety of Trypsin Inhibitors in the Diet: Effects on the Rat Pancreas of Long-Term Feeding of Soy Flour and Soy Protein Isolate

1986 • 40 citations

Regulation of pancreatic enzyme levels by trypsin inhibitors

1970 • 40 citations

Further Studies of the Effects of Raw Soya Flour on the Rat Pancreas

1982 • 40 citations

The USDA trypsin inhibitor study. IV. The chronic effects of soy flour and soy protein isolate on the pancreas in rats after two years

1985 • 39 citations

Cell death (apoptosis) during pancreatic involution after raw soya flour feeding in the rat

1986 • 36 citations

Interaction of Dietary Protein and Trypsin Inhibitor on Plasma Cholecystokinin and Pancreatic Growth in Rats

1986 • 30 citations

The effect of dietary raw and autoclaved soya-bean protein fractions on growth, pancreatic enlargement and pancreatic enzymes in rats

1982 • 29 citations

Nutritional Value and Safety of Methionine Derivatives, Isomeric Dipeptides and Hydroxy Analogs in Mice

1988 • 28 citations

Effect of Soybean Trypsin Inhibitor on Methionine and Cystine Utilization

1963 • 28 citations

Localization of pancreatic enzyme secretion-stimulating activity and trypsin inhibitory activity in zymogen granule of the rat pancreas

1986 • 28 citations

Rapid changes in pancreatic DNA, RNA and protein in the rat during pancreatic enlargement and involution.

1981 • 25 citations

Cholecystokinin

1986 • 25 citations

Gastroenteropancreatic Peptides and the Central Nervous System

1987 • 23 citations

Pancreatic Response to Dietary Trypsin Inhibitor: Variations Among Species

1986 • 21 citations

Growth retardation and pancreatic enlargement in rats due to p-aminobenzamide

1968 • 20 citations

The USDA trypsin inhibitor study. III. Sequential development of pancreatic pathology in rats

1985 • 19 citations

Effect of Sulfur Amino Acid Supplementation of Raw Soy Flour on the Growth and Pancreatic Weights of Rats

1987 • 19 citations

Effects of Camostat, a Synthetic Protease Inhibitor, on Endocrine and Exocrine Pancreas of the Rat

1988 • 19 citations

Atropine-Nonsensitive Feedback Regulatory Mechanism of Rat Pancreatic Enzyme Secretion in Response to Food Protein Intake

1987 • 15 citations

The effect of methionine supplementation on the levels of pancreatopeptidase E, trypsin, chymotrypsin and amylase in the pancreas of chicks receiving raw and heated soya-bean diets

1972 • 15 citations

The Trophic Effect on the Pancreas of Long-Term Continuous Intravenous Infusion of Secretin and a Cholecystokinin-Like Peptide in Rats

1986 • 14 citations

Studies in Mice on the Isolation and Characterization of Growth Inhibitors from Soybeans

1974 • 12 citations

Stimulation of pancreatic secretory process in the rat by low-molecular weight proteinase inhibitor

1987 • 12 citations

Comparative subacute effects of dietary raw soya flour on the pancreas of three species, the marmoset, mouse and rat

1987 • 12 citations

Negative Feedback Inhibition of Pancreatic Exocrine Secretion in Humans

1986 • 12 citations

The failure of long‐term feeding of raw soy flour, in the presence or absence of Azaserine, to induce carcinogenic changes in the mouse pancreas

1986 • 11 citations

Effects of feeding partial and intermittent raw soya flour diets on the rat pancreas

1986 • 11 citations

Effect of synthetic trypsin inhibitor on plasma immunoreactive cholecystokinin in rats

1987 • 11 citations

Pancreatic secretion in the rat influenced by the low molecular weight serine proteinase inhibitor Gabexate mesilate

1986 • 9 citations

Random or selective cell death during pancreatic involution following withdrawal of raw soya flour feeding in the rat

1986 • 8 citations

Development of a pilot plant process for the preparation of a soy trypsin inhibitor concentrate

1985 • 7 citations

Comparative effects of feeding a protease inhibitor-enriched potato protein concentrate and soy flour to rats

1985 • 7 citations

Development of a pilot-plant process for the preparation of a trypsin inhibitor-rich fraction from potatoes

1982 • 5 citations

Subcutaneous Administration of the Synthetic Trypsin Inhibitor Foy-305 Induces Hypertrophy of the Exocrine Pancreas

1987 • 5 citations

Small bowel bypass prevents the trophic action of cholecystokinin on the rat pancreas

1987 • 4 citations

A kinetic analysis of the inhibition of rat and bovine trypsins by naturally occurring protease inhibitors

1986 • 4 citations

Recent advances in pancreatic physiology: summary of a conference.

1981 • 4 citations

Natural plant enzyme inhibitors: comparison of the action of tuber protease inhibitors on animal pancreatic systems.

1985 • 4 citations