A simple method for estimating global DNA methylation using bisulfite PCR of repetitive DNA elements

Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands.

1996 • 5,667 citations

The fundamental role of epigenetic events in cancer

2002 • 5,532 citations

Hypomethylation distinguishes genes of some human cancers from their normal counterparts

1983 • 2,392 citations

The Role of DNA Methylation in Mammalian Epigenetics

2001 • 1,956 citations

High sensitivity mapping of methylated cytosines

1994 • 1,863 citations

COBRA: a sensitive and quantitative DNA methylation assay

1997 • 1,184 citations

The essentials of DNA methylation

1992 • 960 citations

DNMT1 forms a complex with Rb, E2F1 and HDAC1 and represses transcription from E2F-responsive promoters

2000 • 938 citations

A common mutation in the 5,10-methylenetetrahydrofolate reductase gene affects genomic DNA methylation through an interaction with folate status

2002 • 918 citations

5-Methylcytosine as an Endogenous Mutagen in the Human LDL Receptor and p53 Genes

1990 • 643 citations

Impact of aging on DNA methylation

2003 • 421 citations

Changes in DNA Methylation in Neoplasia: Pathophysiology and Therapeutic Implications

2001 • 414 citations

Rapid quantitation of methylation differences at specific sites using methylation-sensitive single nucleotide primer extension (Ms-SNuPE)

1997 • 369 citations

CpG-Island Methylation in Aging and Cancer

2000 • 302 citations

Increased cytosine DNA-methyltransferase activity is target-cell-specific and an early event in lung cancer.

1996 • 237 citations

Does SINE evolution preclude Alu function?

1998 • 233 citations

LINE Drive

2002 • 194 citations

Insertion and/or deletion of many repeated DNA sequences in human and higher ape evolution.

1986 • 183 citations

DNA methylation in the Alu sequences of diploid and haploid primary human cells.

1993 • 175 citations

Evaluation of a potential epigenetic biomarker by quantitative methyl‐single nucleotide polymorphism analysis

2002 • 175 citations

DNA methylation in the fungi.

1984 • 139 citations

Determination of 5-methylcytosine from plant DNA by high-performance liquid chromatography

1981 • 126 citations

DNA methylation analysis a review of current methodologies

1999 • 102 citations

Analyses of Secondary Structures in DNA by Pyrosequencing

1999 • 101 citations

The Host Defence Function of Genomic Methylation Patterns

2007 • 98 citations

Differentiation of two mouse cell lines is associated with hypomethylation of their genomes.

1984 • 96 citations

Densities, length proportions, and other distributional features of repetitive sequences in the human genome estimated from 430 megabases of genomic sequence

2000 • 81 citations

Azacitidine: 10 years later.

1987 • 55 citations

Differentiation of Two Mouse Cell Lines Is Associated with Hypomethylation of Their Genomes

1984 • 35 citations