Evidence for the presence of a proton pump of the vacuolar H(+)-ATPase type in the ruffled borders of osteoclasts.

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

A METHOD FOR THE RAPID DETERMINATION OF ALKALINE PHOSPHATASE WITH FIVE CUBIC MILLIMETERS OF SERUM

1946 • 3,045 citations

ACIDIFICATION OF THE ENDOCYTIC AND EXOCYTIC PATHWAYS

1986 • 1,977 citations

A new method of preparing gold probes for multiple-labeling cytochemistry.

1985 • 1,417 citations

A TECHNIQUE FOR ULTRACRYOTOMY OF CELL SUSPENSIONS AND TISSUES

1973 • 1,057 citations

Ultrastructural localization of intracellular antigens by the use of protein A-gold complex.

1978 • 992 citations

Osteoclastic Bone Resorption by a Polarized Vacuolar Proton Pump

1989 • 864 citations

Cell-mediated extracellular acidification and bone resorption: evidence for a low pH in resorbing lacunae and localization of a 100-kD lysosomal membrane protein at the osteoclast ruffled border.

1985 • 738 citations

Use of colloidal gold particles in double-labeling immunoelectron microscopy of ultrathin frozen tissue sections.

1981 • 387 citations

THE EFFECTS OF PARATHYROID HORMONE, COLCHICINE, AND CALCITONIN ON THE ULTRASTRUCTURE AND THE ACTIVITY OF OSTEOCLASTS IN ORGAN CULTURE

1974 • 343 citations

Cellular biology and biochemical mechanism of bone resorption. A review of recent developments on the formation, activation, and mode of action of osteoclasts.

1988 • 332 citations

Isolation of genes encoding the Neurospora vacuolar ATPase. Analysis of vma-1 encoding the 67-kDa subunit reveals homology to other ATPases.

1988 • 236 citations

Characterization of gastric mucosal membranes. IX. Fractionation and purification of K+-ATPase-containing vesicles by zonal centrifugation and free-flow electrophoresis technique

1977 • 200 citations

Isolation of genes encoding the Neurospora vacuolar ATPase. Analysis of vma-2 encoding the 57-kDa polypeptide and comparison to vma-1.

1988 • 177 citations

Organization of osteoclast microfilaments during the attachment to bone surface in vitro

1989 • 173 citations

The lysosomal proton pump is electrogenic.

1983 • 162 citations

An electrogenic proton-translocating adenosine triphosphatase from bovine kidney medulla.

1984 • 153 citations

Structure, molecular genetics, and evolution of vacuolar H+-ATPases

1989 • 144 citations

Structural studies of the vacuolar membrane ATPase from Neurospora crassa and comparison with the tonoplast membrane ATPase from Zea mays.

1986 • 115 citations

The sulphatase of ox liver. 2. The purification and properties of sulphatase A

1953 • 110 citations

Characterization of the subunit structure of the maize tonoplast ATPase. Immunological and inhibitor binding studies.

1986 • 108 citations

Evidence for a high and specific concentration of (Na+,K+)ATPase in the plasma membrane of the osteoclast

1986 • 104 citations

The sulphatase of ox liver

1971 • 87 citations

Humoral and ionic regulation of osteoclast acidity

1986 • 73 citations

High active isoenzyme of carbonic anhydrase in rat calvaria osteoclasts

1983 • 68 citations

Ultracytochemical evidence for a proton-pump adenosine triphosphatase in chick osteoclasts

1986 • 55 citations

Immunoelectron microscopic localization of carbonic anhydrase III in rat skeletal muscle

1986 • 18 citations

Consecutive expression of carbonic anhydrase isoenzymes during development of rat liver and skeletal muscle differentiation.

1989 • 15 citations

Osteoclasts and a small population of peripheral blood cells share common surface antigens

1990 • 12 citations