Inhibition of Translation and Induction of Apoptosis by Bunyaviral Nonstructural Proteins Bearing Sequence Similarity to Reaper

The Release of Cytochrome c from Mitochondria: A Primary Site for Bcl-2 Regulation of Apoptosis

1997 • 4,728 citations

Mechanisms of Caspase Activation and Inhibition during Apoptosis

2002 • 1,731 citations

Cell Death in Development

1999 • 1,567 citations

Prediction of transmembrane alpha-helices in prokaryotic membrane proteins: the dense alignment surface method

1997 • 1,043 citations

Apoptosis in development

2000 • 1,012 citations

Ubiquitin Protein Ligase Activity of IAPs and Their Degradation in Proteasomes in Response to Apoptotic Stimuli

2000 • 989 citations

Ubiquitin-protein ligase activity of X-linked inhibitor of apoptosis protein promotes proteasomal degradation of caspase-3 and enhances its anti-apoptotic effect in Fas-induced cell death

2001 • 644 citations

HtrA2 Promotes Cell Death through Its Serine Protease Activity and Its Ability to Antagonize Inhibitor of Apoptosis Proteins

2002 • 550 citations

The Serine Protease Omi/HtrA2 Regulates Apoptosis by Binding XIAP through a Reaper-like Motif

2002 • 533 citations

New mammalian expression vectors

1990 • 525 citations

The Drosophila Caspase Inhibitor DIAP1 Is Essential for Cell Survival and Is Negatively Regulated by HID

1999 • 499 citations

Exploiting the past and the future in protein secondary structure prediction

1999 • 493 citations

Induction of apoptosis by Drosophila reaper, hid and grim through inhibition of IAP function

2000 • 448 citations

To kill or be killed: viral evasion of apoptosis

2002 • 429 citations

The human cytosolic molecular chaperones hsp90, hsp70 (hsc70) and hdj-1 have distinct roles in recognition of a non-native protein and protein refolding.

1996 • 424 citations

Hid, Rpr and Grim negatively regulate DIAP1 levels through distinct mechanisms

2002 • 364 citations

How cells die: Apoptosis pathways☆☆☆

2001 • 313 citations

Regulation of Drosophila IAP1 degradation and apoptosis by reaper and ubcD1

2002 • 272 citations

Irresistible IRES

2001 • 253 citations

Bunyamwera bunyavirus nonstructural protein NSs is a nonessential gene product that contributes to viral pathogenesis

2001 • 226 citations

Bunyamwera Bunyavirus Nonstructural Protein NSs Counteracts the Induction of Alpha/Beta Interferon

2002 • 214 citations

Reaper eliminates IAP proteins through stimulated IAP degradation and generalized translational inhibition

2002 • 199 citations

Cell death regulation by the mammalian IAP antagonist Diablo/Smac.

2002 • 173 citations

Bc1-2 protects mice against fatal alphavirus encephalitis.

1996 • 172 citations

Influenza Virus NS1 Protein Induces Apoptosis in Cultured Cells

2001 • 165 citations

reaperis required for neuroblast apoptosis duringDrosophiladevelopment

2002 • 160 citations

Emerging Viruses: The Bunyaviridae

1997 • 139 citations

HIV-1 Vpr Induces Apoptosis through Caspase 9 in T Cells and Peripheral Blood Mononuclear Cells

2002 • 139 citations

sickle, a Novel Drosophila Death Gene in the reaper/hid/grim Region, Encodes an IAP-Inhibitory Protein

2002 • 131 citations

Apoptosis in Coxsackievirus B3-Caused Diseases: Interaction between the Capsid Protein VP2 and the Proapoptotic Protein Siva

2000 • 131 citations

Scythe: a novel reaper-binding apoptotic regulator

1998 • 127 citations

The Damage-Responsive Drosophila Gene sickle Encodes a Novel IAP Binding Protein Similar to but Distinct from reaper, grim, and hid

2002 • 121 citations

Mechanisms and control of programmed cell death in invertebrates

1998 • 119 citations

Morgue mediates apoptosis in the Drosophila melanogaster retina by promoting degradation of DIAP1

2002 • 118 citations

Drosophila sickle Is a Novel grim-reaper Cell Death Activator

2002 • 114 citations

Reversible inhibition of Hsp70 chaperone function by Scythe and Reaper

2001 • 100 citations

Distinct cell killing properties of the Drosophila reaper, head involution defective, and grim genes

1998 • 100 citations

REGULATORS OF APOPTOSIS ON THE ROAD TO PERSISTENT ALPHAVIRUS INFECTION

1997 • 99 citations

Attracting the translation machinery to internal ribosome entry sites

2001 • 97 citations

Induction of apoptosis by La Crosse virus infection and role of neuronal differentiation and human bcl-2 expression in its prevention

1996 • 97 citations

Apoptosis Induced by Drosophila Reaper and Grim in a Human System

1998 • 93 citations

Jafrac2 is an IAP antagonist that promotes cell death by liberating Dronc from DIAP1

2002 • 90 citations

Reaper-induced dissociation of a Scythe-sequestered cytochrome c-releasing activity

1999 • 85 citations

Reaper-induced apoptosis in a vertebrate system

1997 • 80 citations

GH3, a novel proapoptotic domain in Drosophila Grim, promotes a mitochondrial death pathway

2002 • 78 citations

Regulation and execution of apoptosis duringDrosophila development

2000 • 77 citations

Characterization of Reaper- and FADD-Induced Apoptosis in a Lepidopteran Cell Line

1997 • 69 citations

The RHG motifs of Drosophila Reaper and Grim are important for their distinct cell death-inducing abilities

2001 • 64 citations

Apoptosis Is Induced by Hantaviruses in Cultured Cells

1999 • 59 citations

The Hepatitis C Virus Core Protein Interacts with NS5A and Activates Its Caspase-Mediated Proteolytic Cleavage

2001 • 56 citations

The Apoptotic Capability of Coxsackievirus B3 Is Influenced by the Efficient Interaction between the Capsid Protein VP2 and the Proapoptotic Host Protein Siva

2001 • 56 citations

Programmed Cell Death in Virus Infections of the Nervous System

2001 • 54 citations

Adenovirus encoding HIV-1 Vpr activates caspase 9 and induces apoptotic cell death in both p53 positive and negative human tumor cell lines

2002 • 53 citations

Apoptotic Activity of REAPER Is Distinct from Signaling by the Tumor Necrosis Factor Receptor 1 Death Domain

1996 • 48 citations

Crk is required for apoptosis in Xenopus egg extracts

1997 • 48 citations

Caspase Activation Is Required for Permissive Replication of Aleutian Mink Disease Parvovirus in Vitro

2002 • 46 citations

The IAP Proteins: Caspase Inhibitors and Beyond

2000 • 45 citations

Neurovirology and developmental neurobiology

2001 • 17 citations

Genetics, infectivity and virulence of California serogroup viruses

1992 • 16 citations

The Concept of Neurotropism and Selective Vulnerability (“Pathoclisis”) in Virus Infections of the Nervous System — A Historical Overview

2001 • 11 citations

Slow and Persistent Virus Infections of Neurones — A Compromise for Neuronal Survival

2001 • 10 citations

The Mechanisms of Direct, Virus-Induced Destruction of Neurons

2001 • 6 citations