Deletion of 5'-coding sequences of the cellular p53 gene in mouse erythroleukemia: a novel mechanism of oncogene regulation.

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mpl8 and pUC19 vectors

1985 • 15,222 citations

Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I

1977 • 12,015 citations

Compilation and analysis of sequences upstream from the translational start site in eukaryotic mRNAs

1984 • 3,334 citations

A general method for isolation of high molecular weight DNA from eukaryotes

1976 • 2,827 citations

Construction of improved M13 vectors using oligodeoxynucleotide-directed mutagenesis

1983 • 2,609 citations

T antigen is bound to a host protein in SY40-transformed cells

1979 • 2,378 citations

Characterization of a 54K Dalton cellular SV40 tumor antigen present in SV40-transformed cells and uninfected embryonal carcinoma cells

1979 • 1,830 citations

Monoclonal antibodies specific for simian virus 40 tumor antigens

1981 • 1,110 citations

Adenovirus E1b-58kd tumor antigen and SV40 large tumor antigen are physically associated with the same 54 kd cellular protein in transformed cells

1982 • 883 citations

THE MOLECULAR GENETICS OF CELLULAR ONCOGENES

1984 • 765 citations

Cooperation between gene encoding p53 tumour antigen and ras in cellular transformation

1984 • 761 citations

Participation of p53 cellular tumour antigen in transformation of normal embryonic cells

1984 • 754 citations

Detection of a transformation-related antigen in chemically induced sarcomas and other transformed cells of the mouse.

1979 • 736 citations

The Action of Oncogenes in the Cytoplasm and Nucleus

1985 • 708 citations

Cellular immortalization by a cDNA clone encoding the transformation-associated phosphoprotein p53

1984 • 606 citations

Growth regulation of a cellular tumour antigen, p53, in nontransformed cells

1984 • 524 citations

Post-translational regulation of the 54K cellular tumor antigen in normal and transformed cells.

1981 • 491 citations

Major deletions in the gene encoding the p53 tumor antigen cause lack of p53 expression in HL-60 cells.

1985 • 414 citations

Specific interaction between the p53 cellular tumour antigen and major heat shock proteins

1986 • 354 citations

Sequential expression of protooncogenes during lectin-stimulated mitogenesis of normal human lymphocytes.

1986 • 335 citations

Rearrangements of the cellular p53 gene in erythroleukaemic cells transformed by Friend virus

1985 • 334 citations

Two distinct mechanisms regulate the levels of a cellular tumor antigen, p53.

1983 • 313 citations

The ubiquitin system: functions and mechanisms

1985 • 298 citations

Monoclonal antibody analysis of p53 expression in normal and transformed cells

1986 • 285 citations

Microinjection of monoclonal antibody to protein p53 inhibits serum-induced DNA synthesis in 3T3 cells.

1982 • 279 citations

Reconstitution of p53 expression in a nonproducer Ab-MuLV-transformed cell line by transfection of a functional p53 gene

1984 • 269 citations

A monoclonal antibody that recognizes B cells and B cell precursors in mice.

1981 • 260 citations

Association of a murine 53,000-dalton phosphoprotein with simian virus 40 large-T antigen in transformed cells

1980 • 222 citations

Overproduction of p53 antigen makes established cells highly tumorigenic

1985 • 217 citations

Role of the p53 protein in cell proliferation as studied by microinjection of monoclonal antibodies.

1984 • 216 citations

A single gene and a pseudogene for the cellular tumour antigen p53

1983 • 208 citations

Abelson murine leukemia virus-induced tumors elicit antibodies against a host cell protein, P50

1980 • 200 citations

SV40-53K antigen: A possible role for 53K in normal cells

1981 • 187 citations

Analysis of the gene coding for the murine cellular tumour antigen p53.

1984 • 182 citations

The cellular oncogene p53 can be activated by mutagenesis

1985 • 181 citations

The SV40 a gene product is required for the production of a 54,000 MW cellular tumor antigen

1979 • 179 citations

Identification of the p53 protein domain involved in formation of the simian virus 40 large T-antigen-p53 protein complex

1986 • 175 citations

Radioimmunoassay of the cellular protein p53 in mouse and human cell lines.

1982 • 172 citations

Analysis of human p53 proteins and mRNA levels in normal and transformed cells

1986 • 143 citations

Precise epitope mapping of the murine transformation-associated protein, p53.

1985 • 139 citations

Phage Lambda and Molecular Cloning

1983 • 135 citations

DNA as substrate for packaging into bacteriophage lambda, in vitro

1975 • 120 citations

The p53 cellular tumor antigen: gene structure, expression and protein properties

1985 • 108 citations

Inactivation of p53 gene expression by an insertion of Moloney murine leukemia virus-like DNA sequences.

1984 • 106 citations

Isolation of the bacteriophage lambda A-gene protein.

1975 • 102 citations

Increased concentration of an apparently identical cellular protein in cells transformed by either Abelson murine leukemia virus or other transforming agents

1981 • 100 citations

Expression of the p53 protein during the cell cycle of human peripheral blood lymphocytes

1985 • 96 citations

The 53,000-dalton cellular protein and its role in transformation.

1983 • 91 citations

Cloning and expression analysis of full length mouse cDNA sequences encoding the transformation associated protein p53

1984 • 85 citations

Tumorigenicity of fibroblast lines expressing the adenovirus E1a, cellular p53, or normal c-myc genes.

1986 • 85 citations

An embryo protein induced by SV40 virus transformation of mouse cells

1980 • 80 citations

Protein p53 and inducer-mediated erythroleukemia cell commitment to terminal cell division.

1983 • 57 citations

Expression of a transformation-related protein (p53) in the malignant stage of Friend virus-induced diseases

1983 • 48 citations

Reduction in p53 synthesis during differentiation of Friend‐erythroleukemia cells

1983 • 22 citations