A New Platelet-Derived Growth Factor-Regulated Genomic Element Which Binds a Serine/Threonine Phosphoprotein Mediates Induction of the Slow Immediate-Early Gene MCP-1

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

1984 • 6,459 citations

Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogene

1984 • 3,150 citations

Cell-specific regulation of the c-myc gene by lymphocyte mitogens and platelet-derived growth factor

1983 • 2,350 citations

Current Protocols in Molecular Biology

1989 • 1,916 citations

NF-κB: A pleiotropic mediator of inducible and tissue-specific gene control

1989 • 1,622 citations

The inducible transcription activator NF-κB: regulation by distinct protein subunits

1991 • 1,079 citations

PRIMARY RESPONSE GENES INDUCED BY GROWTH FACTORS AND TUMOR PROMOTERS

1991 • 1,078 citations

Identification of two distinct regulatory regions adjacent to the human β-interferon gene

1983 • 1,076 citations

Molecular cloning of gene sequences regulated by platelet-derived growth factor

1983 • 989 citations

Isolation and properties of cDNA clones encoding SRF, a transcription factor that binds to the c-fos serum response element

1988 • 983 citations

Expression of a set of growth-related immediate early genes in BALB/c 3T3 cells: coordinate regulation with c-fos or c-myc.

1987 • 888 citations

Identification of a protein-binding site that mediates transcriptional response of the c-fos gene to serum factors

1986 • 883 citations

Transient accumulation of c-fos RNA following serum stimulation requires a conserved 5′ element and c-fos 3′ sequences

1985 • 871 citations

Induction of DNA synthesis in BALB/c 3T3 cells by serum components: Reevaluation of the commitment process

1977 • 695 citations

The SIF binding element confers sis/PDGF inducibility onto the c-fos promoter.

1990 • 615 citations

Identification of a set of genes expressed during the G0/G1 transition of cultured mouse cells.

1985 • 589 citations

Complexity of the early genetic response to growth factors in mouse fibroblasts.

1988 • 579 citations

Cloning and expression of JE, a gene inducible by platelet-derived growth factor and whose product has cytokine-like properties.

1988 • 444 citations

Identification and purification of a polypeptide that binds to the c-fos serum response element.

1987 • 398 citations

Induction of proto-oncogene fos transcription through the adenylate cyclase pathway: characterization of a cAMP-responsive element.

1988 • 391 citations

Ras-Independent Growth Factor Signaling by Transcription Factor Tyrosine Phosphorylation

1993 • 345 citations

Inducible binding of a factor to the c-fos enhancer

1986 • 310 citations

The SRE: a growth factor responsive transcriptional regulator.

1990 • 287 citations

Regulation of c-myc transcription and mRNA abundance by serum growth factors and cell contact.

1986 • 254 citations

The c-fos serum response element responds to protein kinase C-dependent and -independent signals but not to cyclic AMP.

1988 • 245 citations

Distinct Protein Targets for Signals Acting at the c- fos Serum Response Element

1991 • 244 citations

Mutation of the c-fos gene dyad symmetry element inhibits serum inducibility of transcription in vivo and the nuclear regulatory factor binding in vitro.

1987 • 238 citations

The Human Homolog of the JE Gene Encodes a Monocyte Secretory Protein

1989 • 227 citations

Multiple sequence elements in the c-fos promoter mediate induction by cAMP.

1989 • 225 citations

Multiple sequence elements of a single functional class are required for cyclic AMP responsiveness of the mouse c-fos promoter.

1989 • 220 citations

Functional serum response elements upstream of the growth factor-inducible gene zif268.

1989 • 180 citations

Inducible binding of a factor to the c-fos regulatory region.

1987 • 168 citations

Purification of the c-fos enhancer-binding protein.

1987 • 156 citations

Serum-Inducible Genes

1989 • 143 citations

v-Src activates mitogen-responsive transcription factor Egr-1 via serum response elements

1991 • 97 citations

Cell Cycle Analysis of E2F in Primary Human T Cells Reveals Novel E2F Complexes and Biochemically Distinct Forms of Free E2F

1993 • 94 citations

The serum response factor is extensively modified by phosphorylation following its synthesis in serum-stimulated fibroblasts.

1991 • 92 citations

A novel 7-nucleotide motif located in 3' untranslated sequences of the immediate-early gene set mediates platelet-derived growth factor induction of the JE gene.

1992 • 85 citations

Platelet-derived growth factor-inducible genes respond differentially to at least two distinct intracellular second messengers.

1987 • 84 citations

Glucocorticoids inhibit the transcriptional induction of JE, a platelet-derived growth factor-inducible gene

1991 • 63 citations

MGSA/GRO transcription is differentially regulated in normal retinal pigment epithelial and melanoma cells

1994 • 60 citations

Transcriptional regulatory elements downstream of the JunB gene.

1993 • 51 citations

PDGF-induced Egr-1 expression in rat mesangial cells is mediated through upstream serum response elements

1993 • 48 citations

Interleukin‐1 is a potent regulator of JE and KC gene expression in quiescent BALB/c fibroblasts

1989 • 38 citations

Evidence for a novel signal transduction pathway activated by platelet-derived growth factor and by double-stranded RNA.

1989 • 30 citations

Mitogenic activation of normal T cells leads to increased initiation of transcription in the c-myc locus.

1988 • 30 citations

Downregulation of JE and KC genes by glucocorticoids does not prevent the G0----G1 transition in BALB/3T3 cells.

1992 • 19 citations

Identification of a Multiprotein Complex Interacting with the c-fos Serum Response Element

1991 • 17 citations

Labile repressors are involved in the transcriptional control of PDGF-responsive genes.

1989 • 12 citations