Negative and positive regulation by transcription factor cAMP response element-binding protein is modulated by phosphorylation.

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

1984 • 6,459 citations

Recombinant Genomes Which Express Chloramphenicol Acetyltransferase in Mammalian Cells

1982 • 3,106 citations

Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factor

1987 • 3,057 citations

Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133

1989 • 2,486 citations

CAT constructions with multiple unique restriction sites for the functional analysis of eukaryotic promoters and regulatory elements

1987 • 1,792 citations

Identification of a cyclic-AMP-responsive element within the rat somatostatin gene.

1986 • 1,424 citations

Binding of a nuclear protein to the cyclic-AMP response element of the somatostatin gene

1987 • 1,364 citations

Phosphorylation-induced binding and transcriptional efficacy of nuclear factor CREB

1988 • 1,321 citations

The jun proto-oncogene is positively autoregulated by its product, Jun/AP-1

1988 • 1,256 citations

Identification of two distinct regulatory regions adjacent to the human β-interferon gene

1983 • 1,076 citations

Transcription factor ATF cDNA clones: an extensive family of leucine zipper proteins able to selectively form DNA-binding heterodimers.

1989 • 1,046 citations

Positive and negative regulation of transcription in vitro: Enhancer-binding protein AP-2 is inhibited by SV40 T antigen

1987 • 969 citations

Activation of transcription by two factors that bind promoter and enhancer sequences of the human metallothionein gene and SV40

1987 • 762 citations

Jun-B differs in its biological properties from, and is a negative regulator of, c-Jun

1989 • 698 citations

Induction of proto-oncogene JUN/AP-1 by serum and TPA

1988 • 689 citations

Transcriptional autoregulation of the proto-oncogene fos

1988 • 630 citations

Transcriptional activation of c-jun during the G0/G1 transition in mouse fibroblasts

1988 • 578 citations

Negative Regulation by Glucocorticoids Through Interference with a cAMP Responsive Enhancer

1988 • 502 citations

jun-B inhibits and c-fos stimulates the transforming and trans-activating activities of c-jun

1989 • 488 citations

Hormone-mediated repression: a negative glucocorticoid response element from the bovine prolactin gene.

1988 • 485 citations

Two tobacco DNA-binding proteins with homology to the nuclear factor CREB

1989 • 462 citations

Direct interaction between fos and jun nuclear oncoproteins: role of the 'leucine zipper' domain

1988 • 455 citations

Complete nucleotide sequence of a human c-onc gene: deduced amino acid sequence of the human c-fos protein.

1983 • 446 citations

Induction of protooncogene c-jun by serum growth factors.

1988 • 438 citations

Leucine zipper structure of the protein CRE-BP1 binding to the cyclic AMP response element in brain.

1989 • 396 citations

The carboxy-terminal 30 amino acids of GAL4 are recognized by GAL80

1987 • 349 citations

A family of immunologically related transcription factors that includes multiple forms of ATF and AP-1.

1988 • 259 citations

Steroid receptor-mediated inhibition of rat prolactin gene expression does not require the receptor DNA-binding domain

1988 • 238 citations

Structure of wild-type and mutant mouse β2-microglobulin genes

1982 • 230 citations

Interaction of positive and negative regulatory proteins in the galactose regulon of yeast

1987 • 226 citations

Autoregulation of fos: the dyad symmetry element as the major target of repression.

1989 • 211 citations

Both the basic region and the ‘leucine zipper’ domain of the cyclic AMP response element binding (CREB) protein are essential for transcriptional activation.

1990 • 196 citations

Trans-repression of the mouse c-fos promoter: A novel mechanism of fos-mediated trans-regulation

1989 • 187 citations

SV40 T antigen binding site mutations that affect autoregulation

1983 • 145 citations

A purified Drosophila homeodomain protein represses transcription in vitro

1989 • 142 citations

The Fos and Jun/AP-1 proteins are involved in the downregulation of Fos transcription.

1989 • 135 citations

Transcriptional inhibition by a glucocorticoid receptor-β-galactosidase fusion protein

1988 • 129 citations

A cDNA clone encoding human cAMP-dependent protein kinase catalytic subunit Cα

1988 • 84 citations