Inflammation- and ischemia-induced shedding of venular glycocalyx

Induction by IL 1 and interferon-gamma: tissue distribution, biochemistry, and function of a natural adherence molecule (ICAM-1).

1986 • 2,490 citations

Identification of an inducible endothelial-leukocyte adhesion molecule.

1987 • 1,639 citations

The endothelial surface layer

2000 • 870 citations

Identification of Distinct Luminal Domains for Macromolecules, Erythrocytes, and Leukocytes Within Mammalian Capillaries

1996 • 598 citations

Molecular cloning of syndecan, an integral membrane proteoglycan.

1989 • 505 citations

The Endothelial Glycocalyx Protects Against Myocardial Edema

2003 • 496 citations

Permeation of the luminal capillary glycocalyx is determined by hyaluronan

1999 • 420 citations

Shedding of Syndecan-1 and -4 Ectodomains Is Regulated by Multiple Signaling Pathways and Mediated by a Timp-3–Sensitive Metalloproteinase

2000 • 409 citations

Regulated Shedding of Syndecan-1 and -4 Ectodomains by Thrombin and Growth Factor Receptor Activation

1997 • 375 citations

Role of glycocalyx in leukocyte-endothelial cell adhesion

2002 • 321 citations

Capillary endothelial surface layer selectively reduces plasma solute distribution volume

2000 • 320 citations

Application of the “two-slit” photometric technique to the measurement of microvascular volumetric flow rates

1978 • 309 citations

The cell surface proteoglycan from mouse mammary epithelial cells bears chondroitin sulfate and heparan sulfate glycosaminoglycans.

1985 • 301 citations

Quasi-Periodic Substructure in the Microvessel Endothelial Glycocalyx: A Possible Explanation for Molecular Filtering?

2001 • 274 citations

Heparinase treatment suggests a role for the endothelial cell glycocalyx in regulation of capillary hematocrit

1990 • 226 citations

Role of heparan sulfate in immune system-blood vessel interactions

1993 • 200 citations

Cell surface syndecan-1 on distinct cell types differs in fine structure and ligand binding of its heparan sulfate chains.

1994 • 199 citations

Plasma proteins modify the endothelial cell glycocalyx of frog mesenteric microvessels.

1992 • 191 citations

Inhibition of lymphocyte and neutrophil chemotaxis by pertussis toxin.

1985 • 189 citations

P-selectin must extend a sufficient length from the plasma membrane to mediate rolling of neutrophils.

1995 • 186 citations

Microvascular blood flow resistance: role of endothelial surface layer

1997 • 174 citations

Association of the N-formyl-Met-Leu-Phe receptor in human neutrophils with a GTP-binding protein sensitive to pertussis toxin.

1985 • 159 citations

Permeability of frog mesenteric capillaries after partial pronase digestion of the endothelial glycocalyx.

1990 • 149 citations

Role of syndecan-1 in leukocyte-endothelial interactions in the ocular vasculature.

2002 • 132 citations

Elevated capillary tube hematocrit reflects degradation of endothelial cell glycocalyx by oxidized LDL

2001 • 121 citations

Shedding of heparan sulfate proteoglycan by stimulated endothelial cells: Evidence for proteolysis of cell-surface molecules

1996 • 114 citations

Effects of Shear Stress on Glycosaminoglycan Synthesis in Vascular Endothelial Cells^a

1994 • 107 citations

Cytokines induce HIF-1 DNA binding and the expression of HIF-1-dependent genes in cultured rat enterocytes

2003 • 88 citations

Glycocalyx modulation is a physiological means of regulating cell adhesion

2000 • 87 citations

Differential binding of the lectins Griffonia simplicifolia I and Lycopersicon esculentum to microvascular endothelium: organ-specific localization and partial glycoprotein characterization.

1990 • 83 citations

Rapid modification of the glycocalyx caused by ischemia-reperfusion is inhibited by adenosine A_2Areceptor activation

2003 • 74 citations

Suppression of Syndecan-1 Expression in Endothelial Cells by Tumor Necrosis Factor-α

1996 • 59 citations

Synthesis of sulfated proteoglycans by bovine glomerular endothelial cells in culture

2003 • 51 citations

Lectin analysis of common glycoproteins detected on the surface of continuous microvascular endothelium in situ and in culture: identification of sialoglycoproteins.

1990 • 45 citations

Interactions of mechanotransduction pathways

2003 • 37 citations

Formyl peptide leukocyte chemoattractant uptake and release by cultured human umbilical vein endothelial cells.

1987 • 29 citations

Depleted level of heparan sulfate proteoglycan in the extracellular matrix of endothelial cell cultures exposed to endotoxin

1994 • 24 citations

Differential Lectin Binding to Microvascular Endothelial Glycoconjugates during Normal Angiogenesis in the Chick Chorioallantoic Membrane

1995 • 17 citations