Microphthalmia-associated transcription factor interacts with LEF-1, a mediator of Wnt signaling

Rapid detection of octamer binding proteins with ‘mini extracts’, prepared from a small number of cells

1989 • 4,279 citations

Functional interaction of β-catenin with the transcription factor LEF-1

1996 • 2,847 citations

Wnt signaling: a common theme in animal development

1997 • 2,579 citations

A molecular mechanism for the effect of lithium on development.

1996 • 2,270 citations

XTcf-3 Transcription Factor Mediates β-Catenin-Induced Axis Formation in Xenopus Embryos

1996 • 1,827 citations

Mutations at the mouse microphthalmia locus are associated with defects in a gene encoding a novel basic-helix-loop-helix-zipper protein

1993 • 1,083 citations

Development of several organs that require inductive epithelial-mesenchymal interactions is impaired in LEF-1-deficient mice.

1994 • 969 citations

nacre encodes a zebrafish microphthalmia-related protein that regulates neural-crest-derived pigment cell fate

1999 • 781 citations

Waardenburg syndrome type 2 caused by mutations in the human microphthalmia (MITF) gene

1994 • 661 citations

microphthalmia, a critical factor in melanocyte development, defines a discrete transcription factor family.

1994 • 652 citations

A natural classification of the basic helix–loop–helix class of transcription factors

1997 • 631 citations

Assembly and function of a TCR alpha enhancer complex is dependent on LEF-1-induced DNA bending and multiple protein-protein interactions.

1995 • 546 citations

An HMG-box-containing T-cell factor required for thymocyte differentiation

1995 • 518 citations

Molecular basis of mouse microphthalmia (mi) mutations helps explain their developmental and phenotypic consequences

1994 • 503 citations

Control of neural crest cell fate by the Wnt signalling pathway

1998 • 501 citations

Structure and function of helix-loop-helix proteins

1994 • 496 citations

TFE3: a helix-loop-helix protein that activates transcription through the immunoglobulin enhancer muE3 motif.

1990 • 484 citations

A line of non‐tumorigenic mouse melanocytes, syngeneic with the B16 melanoma and requiring a tumour promoter for growth

1987 • 475 citations

Mitf from neural crest to melanoma: signal transduction and transcription in the melanocyte lineage

2000 • 465 citations

TRP-2/DT, a new early melanoblast marker, shows that steel growth factor (c-kit ligand) is a survival factor

1992 • 409 citations

Functional Analysis of Microphthalmia-associated Transcription Factor in Pigment Cell-specific Transcription of the Human Tyrosinase Family Genes

1997 • 383 citations

A thymus-specific member of the HMG protein family regulates the human T cell receptor C alpha enhancer.

1991 • 372 citations

Nucleotide sequence of cloned cDNA of human c-myc oncogene

1983 • 316 citations

Induction of Melanocyte-specific Microphthalmia-associated Transcription Factor by Wnt-3a

2000 • 314 citations

Roles of Wnt proteins in neural development and maintenance

2000 • 311 citations

Different cis-Acting Elements Are Involved in the Regulation of TRP1 and TRP2 Promoter Activities by Cyclic AMP: Pivotal Role of M Boxes (GTCATGTGCT) and of Microphthalmia

1998 • 304 citations

The Yin-Yang of TCF/β-Catenin Signaling

1999 • 293 citations

Direct regulation of nacre, a zebrafish MITF homolog required for pigment cell formation, by the Wnt pathway

2000 • 265 citations

Differential expression of the HMG box factors TCF-1 and LEF-1 during murine embryogenesis

1993 • 249 citations

A helix-loop-helix protein related to the immunoglobulin E box-binding proteins.

1990 • 244 citations

Mutations in microphthalmia, the mouse homolog of the human deafness gene MITF, affect neuroepithelial and neural crest-derived melanocytes differently

1998 • 211 citations

Neural crest-directed gene transfer demonstrates Wnt1 role in melanocyte expansion and differentiation during mouse development

2000 • 195 citations

Extensive Alternative Splicing and Dual Promoter Usage Generate Tcf-1 Protein Isoforms with Differential Transcription Control Properties

1996 • 193 citations

CBP/p300 as a co-factor for the Microphthalmia transcription factor

1997 • 177 citations

The hLEF/TCF-1 alpha HMG protein contains a context-dependent transcriptional activation domain that induces the TCR alpha enhancer in T cells.

1993 • 155 citations

Structural organization of the human microphthalmia-associated transcription factor gene containing four alternative promoters

2000 • 141 citations

Identification of a Novel Isoform of Microphthalmia-Associated Transcription Factor That Is Enriched in Retinal Pigment Epithelium

1998 • 136 citations

A Mouse Model for Vitiligo

1986 • 136 citations

Role of Mitf in Differentiation and Transdifferentiation of Chicken Pigmented Epithelial Cell

1998 • 131 citations

An L1 Element Intronic Insertion in the Black-Eyed White (Mitfmi-bw) Gene: The Loss of a Single Mitf Isoform Responsible for the Pigmentary Defect and Inner Ear Deafness

1999 • 111 citations

Analyses of loss-of-function mutations of the MITF gene suggest that haploinsufficiency is a cause of Waardenburg syndrome type 2A.

1996 • 107 citations

Microphthalmia-Associated Transcription Factor as a Regulator for Melanocyte-Specific Transcription of the Human Tyrosinase Gene

1994 • 103 citations

Cloning of the human DOPAchrome tautomerase/tyrosinase-related protein 2 gene and identification of two regulatory regions required for its pigment cell-specific expression.

1994 • 99 citations

Mutation of the MITF gene in albinism-deafness syndrome (Tietz syndrome)

1998 • 99 citations

Structure of the Mouse Tyrosinase-Related Protein-2/Dopachrome Tautomerase (Tyrp2/Dct) Gene and Sequence of Two Novel Slaty Alleles

1995 • 97 citations

Molecular Cloning of cDNA Encoding a Novel Microphthalmia- Associated Transcription Factor Isoform with a Distinct Amino-Terminus

1999 • 93 citations

A Helix-Loop-Helix Protein Related to the Immunoglobulin E Box-Binding Proteins

1990 • 78 citations

A Big Gene Linked to Small Eyes Encodes Multiple Mitf Isoforms: Many Promoters Make Light Work

1998 • 76 citations

Transcriptional Activation of the Melanocyte-Specific Genes by the Human Homolog of the Mouse Microphthalmia Protein

1995 • 71 citations

Differential Importin-α Recognition and Nuclear Transport by Nuclear Localization Signals within the High-Mobility-Group DNA Binding Domains of Lymphoid Enhancer Factor 1 and T-Cell Factor 1

1998 • 69 citations

The semidominant Mi(b) mutation identifies a role for the HLH domain in DNA binding in addition to its role in protein dimerization.

1996 • 43 citations

Molecular cloning of cDNA encoding a human TFEC isoform, a newly identified transcriptional regulator

1997 • 26 citations

Role of Neurofibromin in Modulation of Expression of the Tyrosinase-Related Protein 2 Gene

1998 • 19 citations

Identification of a composite enhancer of the human tyrosinase-related protein 2/DOPAchrome tautomerase gene

2000 • 19 citations

Expression of Tyrosinase-related Protein 2/DOPAchrome Tautomerase in the Retinoblastoma

2001 • 19 citations

Implications of isoform multiplicity of microphthalmia-associated transcription factor in the pathogenesis of auditory-pigmentary syndromes.

1999 • 12 citations

Deleted Work

1955 • 0 citations