14-3-3s regulate fructose-2,6-bisphosphate levels by binding to PKB-phosphorylated cardiac fructose-2,6-bisphosphate kinase/phosphatase

Specificity and mechanism of action of some commonly used protein kinase inhibitors

2000 • 4,109 citations

Cell-penetrating Peptides

2002 • 1,392 citations

PKB/Akt

2001 • 1,066 citations

Role of Translocation in the Activation and Function of Protein Kinase B

1997 • 1,044 citations

Phosphorylation and activation of heart PFK-2 by AMPK has a role in the stimulation of glycolysis during ischaemia

2000 • 796 citations

Structural Analysis of 14-3-3 Phosphopeptide Complexes Identifies a Dual Role for the Nuclear Export Signal of 14-3-3 in Ligand Binding

1999 • 500 citations

14-3-3 Proteins: Active Cofactors in Cellular Regulation by Serine/Threonine Phosphorylation

2002 • 496 citations

Phosphorylation and Activation of Heart 6-Phosphofructo-2-kinase by Protein Kinase B and Other Protein Kinases of the Insulin Signaling Cascades

1997 • 435 citations

Crystal Structure of the 14-3-3ζ:Serotonin N-Acetyltransferase Complex

2001 • 380 citations

The Stimulation of Glycolysis by Hypoxia in Activated Monocytes Is Mediated by AMP-activated Protein Kinase and Inducible 6-Phosphofructo-2-kinase

2002 • 369 citations

Fructose-2,6-Bisphosphate as a Regulatory Molecule in Plants

1990 • 353 citations

Hypoxia-inducible Factor-1-mediated Expression of the 6-Phosphofructo-2-kinase/fructose-2,6-bisphosphatase-3 (PFKFB3) Gene

2002 • 341 citations

PFK-2/FBPase-2: maker and breaker of the essential biofactor fructose-2,6-bisphosphate

2001 • 340 citations

Similar substrate recognition motifs for mammalian AMP‐activated protein kinase, higher plant HMG‐CoA reductase kinase‐A, yeast SNF1, and mammalian calmodulin‐dependent protein kinase I

1995 • 322 citations

14-3-3 Proteins Mediate an Essential Anti-apoptotic Signal

2001 • 305 citations

An inducible gene product for 6-phosphofructo-2-kinase with an AU-rich instability element: Role in tumor cell glycolysis and the Warburg effect

1999 • 281 citations

Phosphorylation‐dependent interactions between enzymes of plant metabolism and 14‐3‐3 proteins

1999 • 280 citations

Activation of protein kinase B β and γ isoforms by insulin in vivo and by 3-phosphoinositide-dependent protein kinase-1 in vitro: comparison with protein kinase B α

1998 • 275 citations

6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE: A METABOLIC SIGNALING ENZYME

1995 • 254 citations

Phosphorylated nitrate reductase from spinach leaves is inhibited by 14-3-3 proteins and activated by fusicoccin

1996 • 252 citations

Roles of the forkhead in rhabdomyosarcoma (FKHR) phosphorylation sites in regulating 14-3-3 binding, transactivation and nuclear targetting

2001 • 234 citations

Mechanisms of control of heart glycolysis

1998 • 159 citations

Interaction of 14-3-3 with a Nonphosphorylated Protein Ligand, Exoenzyme S ofPseudomonas aeruginosa

1999 • 154 citations

Survival-promoting functions of 14-3-3 proteins

2002 • 109 citations

Purification and Characterization of a Novel Xylulose 5-Phosphate-activated Protein Phosphatase Catalyzing Dephosphorylation of Fructose-6-phosphate,2-kinase:Fructose-2,6-bisphosphatase

1995 • 102 citations

Identification of protein phosphorylation sites by a combination of mass spectrometry and solid phase Edman sequencing.

2002 • 77 citations

Heart 6-Phosphofructo-2-kinase Activation by Insulin Results from Ser-466 and Ser-483 Phosphorylation and Requires 3-Phosphoinositide-dependent Kinase-1, but Not Protein Kinase B

1999 • 73 citations

Signaling Pathway Involved in the Activation of Heart 6-Phosphofructo-2-kinase by Insulin

1996 • 67 citations

Phosphorylation of rat hepatic fructose-1,6-bisphosphatase and pyruvate kinase.

1980 • 59 citations

Cyclic AMP suppresses the inhibition of glycolysis by alternative oxidizable substrates in the heart.

1998 • 57 citations

Binding of Regulatory 14-3-3 Proteins to the C Terminus of the Plant Plasma Membrane H+-ATPase Involves Part of Its Autoinhibitory Region

2001 • 48 citations

Increasing fructose 2,6-bisphosphate overcomes hepatic insulin resistance of type 2 diabetes

2002 • 43 citations

6-Phosphofructo-2-kinase/fructose-2,6-bisphosphatase: suiting structure to need, in a family of tissue-specific enzymes

2001 • 40 citations

Regulation of the 14-3-3-binding protein p39 by growth factors and nutrients in rat PC12 pheochromocytoma cells

2002 • 34 citations

The two forms of bovine heart 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase result from alternative splicing

1992 • 31 citations

A rat gene encoding heart 6‐phosphofructo‐2‐kinase/fructose‐2,6‐bisphosphatase

1991 • 31 citations

Partial purification and characterization of a wortmannin-sensitive and insulin-stimulated protein kinase that activates heart 6-phosphofructo-2-kinase

2000 • 30 citations

Phosphorylation and Inactivation of Yeast 6-Phosphofructo-2-kinase Contribute to the Regulation of Glycolysis under Hypotonic Stress

2001 • 27 citations

Affinity purification of diverse plant and human 14-3-3-binding partners

2002 • 21 citations

Differences in fructose‐2,6‐bisphosphate metabolism between sections of developing barley leaves

1992 • 19 citations

14‐3‐3 binding to the IGF‐1 receptor is mediated by serine autophosphorylation¹

2002 • 12 citations

Alternative Splicing of Novel Exons of Rat Heart-Type Fructose-6-phosphate 2-Kinase/Fructose-2,6-bisphosphatase Gene

2001 • 9 citations

Inhibition of 6-phosphofructo-2-kinase activity by mercaptopurines

1992 • 7 citations