HOXB4 enforces equivalent fates of ES-cell-derived and adult hematopoietic cells

LMO2 -Associated Clonal T Cell Proliferation in Two Patients after Gene Therapy for SCID-X1

2003 • 3,480 citations

Osteoblastic cells regulate the haematopoietic stem cell niche

2003 • 3,370 citations

Identification of the haematopoietic stem cell niche and control of the niche size

2003 • 2,900 citations

A role for Wnt signalling in self-renewal of haematopoietic stem cells

2003 • 2,131 citations

Woodchuck Hepatitis Virus Posttranscriptional Regulatory Element Enhances Expression of Transgenes Delivered by Retroviral Vectors

1999 • 1,007 citations

Biology of Hematopoietic Stem Cells and Progenitors: Implications for Clinical Application

2003 • 974 citations

In vivo proliferation and cell cycle kinetics of long-term self-renewing hematopoietic stem cells

1999 • 832 citations

HoxB4 Confers Definitive Lymphoid-Myeloid Engraftment Potential on Embryonic Stem Cell and Yolk Sac Hematopoietic Progenitors

2002 • 767 citations

HOXB4-Induced Expansion of Adult Hematopoietic Stem Cells Ex Vivo

2002 • 707 citations

Murine Leukemia Induced by Retroviral Gene Marking

2002 • 669 citations

Pluripotent, cytokine-dependent, hematopoietic stem cells are immortalized by constitutive Notch1 signaling

2000 • 641 citations

Multiple hematopoietic lineages develop from embryonic stem (ES) cells in culture

1991 • 615 citations

Deregulated homeobox gene expression in cancer: cause or consequence?

2002 • 613 citations

Correction of a Genetic Defect by Nuclear Transplantation and Combined Cell and Gene Therapy

2002 • 612 citations

Overexpression of HOXB4 in hematopoietic cells causes the selective expansion of more primitive populations in vitro and in vivo.

1995 • 606 citations

Differential expression of homeobox genes in functionally distinct CD34+ subpopulations of human bone marrow cells.

1994 • 529 citations

Bethesda proposals for classification of nonlymphoid hematopoietic neoplasms in mice

2002 • 419 citations

Overexpression of the myeloid leukemia–associatedHoxa9 gene in bone marrow cells induces stem cell expansion

2002 • 354 citations

In vitro expansion of hematopoietic stem cells by recombinant TAT-HOXB4 protein

2003 • 297 citations

Differential expression of Hox, Meis1, and Pbx1 genes in primitive cells throughout murine hematopoietic ontogeny

2002 • 288 citations

Retroviral Expression in Embryonic Stem Cells and Hematopoietic Stem Cells

2000 • 277 citations

HOXB4 overexpression mediates very rapid stem cell regeneration and competitive hematopoietic repopulation

2001 • 228 citations

Human hematopoietic stem cells stimulated to proliferate in vitro lose engraftment potential during their S/G2/M transit and do not reenter G0

2000 • 212 citations

Embryonic stem cell virus, a recombinant murine retrovirus with expression in embryonic stem cells.

1990 • 203 citations

Homeobox genes in normal hematopoiesis and leukemia

1992 • 168 citations

Transplantable myeloproliferative disease induced in mice by an interleukin 6 retrovirus.

1992 • 167 citations

Identification of endoglin as a functional marker that defines long-term repopulating hematopoietic stem cells

2002 • 165 citations

High-level ectopic HOXB4 expression confers a profound in vivo competitive growth advantage on human cord blood CD34+ cells, but impairs lymphomyeloid differentiation

2003 • 162 citations

Design of 5′ Untranslated Sequences in Retroviral Vectors Developed for Medical Use

1999 • 155 citations

Deregulated expression of HOXB4 enhances the primitive growth activity of human hematopoietic cells

2002 • 139 citations

Distinct role of gp130 activation in promoting self-renewal divisions by mitogenically stimulated murine hematopoietic stem cells

2001 • 137 citations

A Novel Immunodeficient Mouse Model-RAG2 gamma Cytokine Receptor Chain Double Mutants-Requiring Exogenous Cytokine Administration for Human Hematopoietic Stem Cell Engraftment Common

1999 • 130 citations

Leukemic transformation of normal murine erythroid progenitors: v- and c-ErbB act through signaling pathways activated by the EpoR and c-Kit in stress erythropoiesis

2001 • 121 citations

Directed differentiation and mass cultivation of pure erythroid progenitors from mouse embryonic stem cells

2004 • 108 citations

Expression of the GM-CSF gene after retroviral transfer in hematopoietic stem cell lines induces synchronous granulocyte-macrophage differentiation

1991 • 87 citations

Expression and function of CD105 during the onset of hematopoiesis from Flk1+ precursors

2001 • 84 citations

The Competitive Nature of HOXB4-Transduced HSC Is Limited by PBX1

2003 • 84 citations

The EndoglinPositive Sca-1Positive RhodamineLow Phenotype Defines a Near-Homogeneous Population of Long-Term Repopulating Hematopoietic Stem Cells

2003 • 78 citations

Retroviral vector-mediated expression of HoxB4 in hematopoietic cells using a novel coexpression strategy

2001 • 72 citations

A Model for Nonstoichiometric, Cotranslational Protein Scission in Eukaryotic Ribosomes

1999 • 70 citations

FMEV vectors: both retroviral long terminal repeat and leader are important for high expression in transduced hematopoietic cells

1998 • 49 citations

Enforced adenoviral vector-mediated expression of HOXB4 in human umbilical cord blood cd34+ cells promotes myeloid differentiation but not proliferation

2003 • 45 citations

Mutagenesis by retroviral transgene insertion: risk assessment and potential alternatives.

2003 • 30 citations

Development of Hematopoietic Repopulating Cells from Embryonic Stem Cells

2003 • 11 citations