Transducer of regulated CREB-binding proteins (TORCs) induce PGC-1α transcription and mitochondrial biogenesis in muscle cells

Calcium's Role in Mechanotransduction during Muscle Development

2014 • 14,293 citations

PGC-1α-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes

2003 • 8,996 citations

Mechanisms Controlling Mitochondrial Biogenesis and Respiration through the Thermogenic Coactivator PGC-1

1999 • 3,923 citations

A Cold-Inducible Coactivator of Nuclear Receptors Linked to Adaptive Thermogenesis

1998 • 3,700 citations

A Mitochondrial Paradigm of Metabolic and Degenerative Diseases, Aging, and Cancer: A Dawn for Evolutionary Medicine

2005 • 3,020 citations

Transcriptional co-activator PGC-1α drives the formation of slow-twitch muscle fibres

2002 • 2,422 citations

Metabolic control through the PGC-1 family of transcription coactivators

2005 • 2,032 citations

Adaptations of skeletal muscle to endurance exercise and their metabolic consequences

1984 • 1,940 citations

Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1

2003 • 1,893 citations

Transcriptional regulatory circuits controlling mitochondrial biogenesis and function

2004 • 1,208 citations

Defects in Adaptive Energy Metabolism with CNS-Linked Hyperactivity in PGC-1α Null Mice

2004 • 1,135 citations

Adaptations of skeletal muscle to exercise: rapid increase in the transcriptional coactivator PGC‐1

2002 • 998 citations

A calcineurin-dependent transcriptional pathway controls skeletal muscle fiber type

1998 • 998 citations

Calcium Ion in Skeletal Muscle: Its Crucial Role for Muscle Function, Plasticity, and Disease

2000 • 956 citations

The CREB coactivator TORC2 is a key regulator of fasting glucose metabolism

2005 • 945 citations

Exercise induces transient transcriptional activation of the PGC‐1α gene in human skeletal muscle

2003 • 868 citations

An autoregulatory loop controls peroxisome proliferator-activated receptor γ coactivator 1α expression in muscle

2003 • 695 citations

Errα and Gabpa/b specify PGC-1α-dependent oxidative phosphorylation gene expression that is altered in diabetic muscle

2004 • 662 citations

Regulation of Mitochondrial Biogenesis in Skeletal Muscle by CaMK

2002 • 659 citations

Exercise Stimulates Pgc-1α Transcription in Skeletal Muscle through Activation of the p38 MAPK Pathway

2005 • 658 citations

The CREB Coactivator TORC2 Functions as a Calcium- and cAMP-Sensitive Coincidence Detector

2004 • 633 citations

The estrogen-related receptor α (ERRα) functions in PPARγ coactivator 1α (PGC-1α)-induced mitochondrial biogenesis

2004 • 600 citations

TORCs

2003 • 583 citations

Bioenergetic Analysis of Peroxisome Proliferator-activated Receptor γ Coactivators 1α and 1β (PGC-1α and PGC-1β) in Muscle Cells

2003 • 528 citations

Effects of low-intensity prolonged exercise on PGC-1 mRNA expression in rat epitrochlearis muscle

2002 • 363 citations

Identification of a family of cAMP response element-binding protein coactivators by genome-scale functional analysis in mammalian cells

2003 • 362 citations

Reduced Differentiation Potential of Primary MyoD−/− Myogenic Cells Derived from Adult Skeletal Muscle

1999 • 344 citations

Transcriptional activators and coactivators in the nuclear control of mitochondrial function in mammalian cells

2002 • 339 citations

Multiple environmental and genetic factors influence skeletal muscle PGC-1α and PGC-1β gene expression in twins

2004 • 274 citations

cDNA Cloning and mRNA Analysis of PGC-1 in Epitrochlearis Muscle in Swimming-Exercised Rats

2000 • 259 citations

C75 increases peripheral energy utilization and fatty acid oxidation in diet-induced obesity

2002 • 257 citations

Multiple environmental and genetic factors influence skeletal muscle PGC-1α and PGC-1β gene expression in twins

2004 • 232 citations

Activation of cAMP Response Element-Mediated Gene Expression by Regulated Nuclear Transport of TORC Proteins

2004 • 227 citations

Mitochondrial Cyclic AMP Response Element-binding Protein (CREB) Mediates Mitochondrial Gene Expression and Neuronal Survival

2005 • 198 citations

Sequential Serum-dependent Activation of CREB and NRF-1 Leads to Enhanced Mitochondrial Respiration through the Induction of Cytochrome c

2000 • 184 citations

Effects of acute bouts of running and swimming exercise on PGC-1α protein expression in rat epitrochlearis and soleus muscle

2004 • 168 citations

Real-time imaging of peroxisome proliferator-activated receptor-γ coactivator-1α promoter activity in skeletal muscles of living mice

2004 • 119 citations

Role of the β3-Adrenergic Receptor and/or a Putative β4-Adrenergic Receptor on the Expression of Uncoupling Proteins and Peroxisome Proliferator-Activated Receptor-γ Coactivator-1

1999 • 99 citations

Dual role of the coactivator TORC2 in modulating hepatic glucose output and insulin signaling

2005 • 69 citations

Transcriptional Regulation of 5-Aminolevulinate Synthase by Phenobarbital and cAMP-Dependent Protein Kinase

1999 • 34 citations

Mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase promoter contains a CREB binding site that regulates cAMP action in Caco-2 cells

2000 • 11 citations