SOCS1 deficiency results in accelerated mammary gland development and rescues lactation in prolactin receptor–deficient mice

A family of cytokine-inducible inhibitors of signalling

1997 • 2,055 citations

Prolactin (PRL) and Its Receptor: Actions, Signal Transduction Pathways and Phenotypes Observed in PRL Receptor Knockout Mice

1998 • 1,846 citations

A new protein containing an SH2 domain that inhibits JAK kinases

1997 • 1,413 citations

Stat5a and Stat5b Proteins Have Essential and Nonessential, or Redundant, Roles in Cytokine Responses

1998 • 1,316 citations

Structure and function of a new STAT-induced STAT inhibitor

1997 • 1,308 citations

Stat5a is mandatory for adult mammary gland development and lactogenesis.

1997 • 1,106 citations

Null mutation of the prolactin receptor gene produces multiple reproductive defects in the mouse.

1997 • 797 citations

SOCS1 Is a Critical Inhibitor of Interferon γ Signaling and Prevents the Potentially Fatal Neonatal Actions of this Cytokine

1999 • 767 citations

Twenty proteins containing a C-terminal SOCS box form five structural classes

1998 • 735 citations

The JAK-binding protein JAB inhibits Janus tyrosine kinase activity through binding in the activation loop

1999 • 712 citations

Defective mammopoiesis, but normal hematopoiesis, in mice with a targeted disruption of the prolactin gene

1997 • 647 citations

Novel insights into erythroid development revealed through in vitro differentiation of GATA-1 embryonic stem cells.

1994 • 574 citations

SOCS1 Deficiency Causes a Lymphocyte-Dependent Perinatal Lethality

1999 • 531 citations

Gigantism in mice lacking suppressor of cytokine signalling-2

2000 • 492 citations

Prolactin (PRL) and Its Receptor: Actions, Signal Transduction Pathways and Phenotypes Observed in PRL Receptor Knockout Mice

1998 • 473 citations

SOCS: physiological suppressors of cytokine signaling

2000 • 457 citations

Liver degeneration and lymphoid deficiencies in mice lacking suppressor of cytokine signaling-1

1998 • 433 citations

SOCS3 Is Essential in the Regulation of Fetal Liver Erythropoiesis

1999 • 372 citations

Prolactin Controls Mammary Gland Development via Direct and Indirect Mechanisms

1999 • 333 citations

Accelerated apoptosis of lymphocytes by augmented induction of Bax in SSI-1 (STAT-induced STAT inhibitor-1) deficient mice

1998 • 290 citations

Suppression of STAT5 Functions in Liver, Mammary Glands, and T Cells in Cytokine-Inducible SH2-Containing Protein 1 Transgenic Mice

1999 • 269 citations

Bcl-2, Bcl-xL and adenovirus protein E1B19kD are functionally equivalent in their ability to inhibit cell death

1997 • 248 citations

Inhibition and Restoration of Prolactin Signal Transduction by Suppressors of Cytokine Signaling

1999 • 197 citations

Prolactin Signaling in Mammary Gland Development

1997 • 174 citations

PTP1D is a positive regulator of the prolactin signal leading to beta-casein promoter activation.

1996 • 144 citations

In situ hybridisation.

1990 • 129 citations

Prolactin signal transduction mechanisms in the mammary gland: the role of the Jak/Stat pathway

1996 • 97 citations

Cytokine‐inducible SH2 protein (CIS3) and JAK2 binding protein (JAB) abolish prolactin receptor‐mediated STAT5 signaling

1998 • 87 citations

SOCS-1, -2, -3: selective targets and functions downstream of the prolactin receptor

1999 • 59 citations

The CIS/JAB family: novel negative regulators of JAK signaling pathways

1998 • 51 citations

Prolactin

1987 • 22 citations

Animal models for the study of milk secretion

1996 • 14 citations