Association of the CYP17 gene and CYP19 gene polymorphisms with risk of endometriosis in Japanese women

Revised American Fertility Society Classification of Endometriosis: 1985

1985 • 1,790 citations

Aromatase expression in endometriosis.

1996 • 520 citations

Polycystic ovaries and premature male pattern baldness are associated with one allele of the steroid metabolism gene CYP17

1994 • 467 citations

Cloning and Sequence of the Human Gene for P450cl7 (Steroid 17α-Hydroxylase/17,20 Lyase): Similarity with the Gene for P450c21

1987 • 415 citations

Tissue-specific expression of the human aromatase cytochrome P-450 gene by alternative use of multiple exons 1 and promoters, and switching of tissue-specific exons 1 in carcinogenesis.

1993 • 361 citations

Genetic influences on endometriosis in an Australian twin sample

1999 • 319 citations

Tissue-specific and hormonally controlled alternative promoters regulate aromatase cytochrome P450 gene expression in human adipose tissue.

1993 • 303 citations

Expression of Aromatase Cytochrome P450 Protein and Messenger Ribonucleic Acid in Human Endometriotic and Adenomyotic Tissues but not in Normal Endometrium1

1997 • 299 citations

A polymorphism in the CYP17 gene increases the risk of breast cancer.

1997 • 250 citations

Cytochrome P450c17alpha gene (CYP17) polymorphism is associated with serum estrogen and progesterone concentrations.

1998 • 243 citations

The familial risk of endometriosis

1993 • 241 citations

Aromatase expression in endometriosis

1996 • 235 citations

The relationship between a polymorphism in CYP17 with plasma hormone levels and breast cancer.

1999 • 228 citations

Human Aromatase: cDNA Cloning, Southern Blot Analysis, and Assignment of the Gene to Chromosome 15

1988 • 227 citations

Immunohistochemical analysis of estrogen and progesterone receptors in endometriosis: comparison with normal endometrium during the menstrual cycle and the effect of medical therapy

1989 • 177 citations

Oestrogen receptor-alpha gene polymorphism is associated with endometriosis, adenomyosis and leiomyomata

2001 • 157 citations

Familial endometriosis

1995 • 155 citations

CYP17 and breast cancer risk: the polymorphism in the 5' flanking area of the gene does not influence binding to Sp-1.

1999 • 154 citations

Aromatase and breast cancer susceptibility.

1999 • 145 citations

A tetranucleotide repeat polymorphism in CYP19 and breast cancer risk

2000 • 144 citations

Association of estrogen receptor gene polymorphisms with endometriosis

1999 • 142 citations

Possible involvement of arylamine N-acetyltransferase 2, glutathione S-transferases M1 and T1 genes in the development of endometriosis

1999 • 135 citations

Detection of aromatase cytochrome P-450 in endometrial biopsy specimens as a diagnostic test for endometriosis

1999 • 134 citations

A rare CYP19 (aromatase) variant may increase the risk of breast cancer

1998 • 123 citations

No association between a polymorphism in the steroid metabolism gene CYP17 and risk of breast cancer

1998 • 118 citations

Constitutional genetic variation at the human aromatase gene (Cyp19) and breast cancer risk

1999 • 114 citations

Glutathione S-transferase M1 gene polymorphism and susceptibility to endometriosis in a French population

1997 • 113 citations

Tetranucleotide repeat polymorphism at the human aromatase cytochrome P-450 gene (CYP19)

1991 • 110 citations

Association betweenCYP17 gene polymorphism and risk of breast cancer in young women

1999 • 108 citations

CYP17 genotype and breast cancer risk.

1998 • 97 citations

Association between CYP17 polymorphisms and the development of breast cancer.

1998 • 95 citations

Polymorphisms in the human aromatase cytochrome P450 gene (CYP19) and breast cancer risk

2000 • 91 citations

Ovarian steroid receptor expression in endometriosis and in two potential parent epithelia: endometrium and peritoneal mesothelium

1992 • 90 citations

Endometriosis: Oestrogen and progesterone receptors in endometriotic tissue and endometrium: comparison of different cycle phases and ages*

1993 • 86 citations

Breast cancer risk associated with polymorphism inCYP19 in Japanese women

2000 • 73 citations

Influence of TNF microsatellite polymorphisms (TNFa) on age-at-onset of insulin-dependent diabetes mellitus

1999 • 34 citations

Use of Molecular Probes to Study Regulation of Aromatase Cytochrome P-4501

1990 • 20 citations

Combined polymorphism associated with a 3-bp deletion in the 5'-flanking region of a tetrameric short tandem repeat at the CYP19 locus.

1997 • 18 citations

A polymorphic tetranucleotide repeat in the CYP19 gene and male breast cancer

2000 • 6 citations