Experimental observations of a nuclear matrix

Cell Biology: a Laboratory Handbook

1995 • 1,226 citations

High mobility of proteins in the mammalian cell nucleus

2000 • 1,163 citations

Organization of the higher-order chromatin loop: specific DNA attachment sites on nuclear scaffold

1984 • 1,088 citations

Identification of a nuclear protein matrix

1974 • 1,016 citations

A new staining procedure for electron microscopical cytology

1969 • 830 citations

The Glucocorticoid Receptor: Rapid Exchange with Regulatory Sites in Living Cells

2000 • 791 citations

XIST RNA paints the inactive X chromosome at interphase: evidence for a novel RNA involved in nuclear/chromosome structure.

1996 • 787 citations

The Organization of Replication and Transcription

1999 • 750 citations

A fixed site of DNA replication in eucaryotic cells

1980 • 669 citations

Fine structural organization of the interphase nucleus in some mammalian cells

1969 • 632 citations

Supercoiled loops and eucaryotic DNA replication

1980 • 626 citations

The dynamics of a pre-mRNA splicing factor in living cells

1997 • 604 citations

Dynamics of DNA Replication Factories in Living Cells

2000 • 572 citations

Isolation, characterization, and structure of the folded interphase genome of Drosophila melanogaster

1976 • 556 citations

Fluorescent labeling of nascent RNA reveals transcription by RNA polymerase II in domains scattered throughout the nucleus

1993 • 541 citations

Mapping replicational sites in the eucaryotic cell nucleus.

1989 • 520 citations

A tissue-specific MAR/SAR DNA-binding protein with unusual binding site recognition

1992 • 508 citations

Supercoils in human dna

1975 • 496 citations

Visualization of replication factories attached to a nucleoskeleton

1993 • 472 citations

Structural organization of nuclear complexes containing DNA-like RNA

1968 • 457 citations

The nuclear matrix: Three-dimensional architecture and protein composition

1982 • 445 citations

Core filaments of the nuclear matrix.

1990 • 436 citations

Biological Significance of Unwinding Capability of Nuclear Matrix-Associating DNAs

1992 • 407 citations

The MAR-binding protein SATB1 orchestrates temporal and spatial expression of multiple genes during T-cell development

2000 • 391 citations

FRAP reveals that mobility of oestrogen receptor-α is ligand- and proteasome-dependent

2000 • 390 citations

Characterization of nuclear structures containing superhelical DNA

1976 • 370 citations

THE ROLE OF THE NUCLEAR MATRIX IN THE ORGANIZATION AND FUNCTION OF DNA

1986 • 360 citations

Nuclear matrix proteins reflect cell type of origin in cultured human cells.

1988 • 318 citations

Lamin proteins form an internal nucleoskeleton as well as a peripheral lamina in human cells

1995 • 315 citations

Transcription occurs at a nucleoskeleton.

1985 • 303 citations

Half a Century of “The Nuclear Matrix”

2000 • 295 citations

Numbers and Organization of RNA Polymerases, Nascent Transcripts, and Transcription Units in HeLa Nuclei

1998 • 292 citations

Purification and biochemical characterization of interchromatin granule clusters

1999 • 285 citations

Intranuclear diffusion and hybridization state of oligonucleotides measured by fluorescence correlation spectroscopy in living cells

1998 • 276 citations

Active and inactive genes localize preferentially in the periphery of chromosome territories.

1996 • 265 citations

Ultrastructural Analysis of Transcription and Splicing in the Cell Nucleus after Bromo-UTP Microinjection

1999 • 256 citations

Identification of a nuclear matrix targeting signal in the leukemia and bone-related AML/CBF-α transcription factors

1997 • 251 citations

The size of chromatin loops in HeLa cells.

1990 • 246 citations

Heterogeneous nuclear RNA-protein fibers in chromatin-depleted nuclei.

1978 • 245 citations

The cellular organization of gene expression

1998 • 243 citations

Searching for a function for nuclear actin

2000 • 235 citations

Subnuclear Trafficking of Estrogen Receptor-α and Steroid Receptor Coactivator-1

2000 • 233 citations

RNA and the Epigenetic Regulation of X Chromosome Inactivation

1998 • 227 citations

Components of the Human SWI/SNF Complex Are Enriched in Active Chromatin and Are Associated with the Nuclear Matrix

1997 • 226 citations

Pre-mRNA splicing and the nuclear matrix.

1987 • 220 citations

An Atlas of Fine Structure. The Cell. Its Organelles and Inclusions.

1966 • 219 citations

Cell biology of transcription and pre-mRNA splicing: nuclear architecture meets nuclear function

2000 • 218 citations

Visualization of a filamentous nucleoskeleton with a 23 nm axial repeat.

1988 • 216 citations

Association of nuclear matrix antigens with exon-containing splicing complexes.

1994 • 214 citations

A coactivator of pre-mRNA splicing

1998 • 212 citations

Quantitative Motion Analysis of Subchromosomal Foci in Living Cells Using Four-Dimensional Microscopy

1999 • 199 citations

Processing of Endogenous Pre-mRNAs in Association with SC-35 Domains Is Gene Specific

1999 • 194 citations

Review: Nuclear Lamins—Structural Proteins with Fundamental Functions

2000 • 194 citations

Chromatin Domains and Prediction of MAR Sequences

1996 • 193 citations

Chromatin Dynamics in Interphase Nuclei and Its Implications for Nuclear Structure

1997 • 193 citations

Movement of nuclear poly(A) RNA throughout the interchromatin space in living cells

1999 • 190 citations

Chromatin architecture and nuclear RNA.

1989 • 187 citations

The cell, its organelles and inclusions : an atlas of fine structure

1966 • 186 citations

Isolation of a protein scaffold from mitotic HeLa cell chromosomes

1977 • 181 citations

Reduced Mobility of the Alternate Splicing Factor (Asf) through the Nucleoplasm and Steady State Speckle Compartments

2000 • 175 citations

Nuclear matrix association of multiple sequence-specific DNA binding activities related to SP-1, ATF, CCAAT, C/EBP, OCT-1, and AP-1

1993 • 175 citations

Identification of nuclear matrix proteins in the cancer and normal rat prostate.

1991 • 168 citations

Serine/threonine phosphatase 1 modulates the subnuclear distribution of pre-mRNA splicing factors.

1996 • 160 citations

Association of Chromosome Territories with the Nuclear Matrix

1999 • 160 citations

Dynamic changes in the higher-level chromatin organization of specific sequences revealed by in situ hybridization to nuclear halos.

1994 • 158 citations

Three-Dimensional Visualization of Transcription Sites and Their Association with Splicing Factor–Rich Nuclear Speckles

1999 • 157 citations

The nuclear matrix revealed by eluting chromatin from a cross-linked nucleus

1997 • 156 citations

The Genomic Sequences Bound to Special AT-rich Sequence-binding Protein 1 (SATB1) In Vivo in Jurkat T Cells Are Tightly Associated with the Nuclear Matrix at the Bases of the Chromatin Loops

1998 • 154 citations

A subset of non-histone nuclear proteins reversibly stabilized by the sulfhydryl cross-linking reagent tetrathionate

1984 • 153 citations

Mechanical continuity and reversible chromosome disassembly within intact genomes removed from living cells

1997 • 152 citations

The Architectural Organization of Nuclear Metabolism

1996 • 150 citations

Preservation of specific RNA distribution within the chromatin-depleted nuclear substructure demonstrated by in situ hybridization coupled with biochemical fractionation.

1991 • 139 citations

Nuclear Organization and Gene Expression

1996 • 136 citations

Nuclear architecture and the induction of chromosomal aberrations

1996 • 131 citations

A nuclear ribonucleoprotein network

1963 • 125 citations

A Nonerythroid Isoform of Protein 4.1R Interacts with the Nuclear Mitotic Apparatus (NuMA) Protein

1999 • 125 citations

Evidence for the Presence of Myosin I in the Nucleus

1997 • 123 citations

hnRNP proteins and B23 are the major proteins of the internal nuclear matrix of HeLa S3 cells

1996 • 121 citations

The SRm160/300 splicing coactivator subunits

2000 • 119 citations

Isolation of a nuclear ribonucleoprotein network that contains heterogeneous RNA and is bound to the nuclear envelope

1975 • 117 citations

Self assembly of NuMA: multiarm oligomers as structural units of a nuclear lattice

1999 • 114 citations

Spatial distribution of DNA loop attachment and replicational sites in the nuclear matrix.

1984 • 113 citations

Ultrastructural Organization and Biochemical Characterization of Chromatin · RNA · Protein Complexes Isolated from Mammalian Cell Nuclei

1975 • 112 citations

Structural Protein 4.1 in the Nucleus of Human Cells: Dynamic Rearrangements during Cell Division

1997 • 107 citations

Specificity and Functional Significance of DNA Interaction with the Nuclear Matrix: New Approaches to Clarify the Old Questions

1996 • 95 citations

The Nuclear Lamina: Molecular Organization and Interaction with Chromatin

1999 • 95 citations

Monoclonal antibodies to heterogeneous nuclear RNA-protein complexes. The core proteins comprise a conserved group of related polypeptides.

1984 • 95 citations

Organization of chromosomes in hela cells: Isolation of histone-depleted nuclei and nuclear scaffolds

1980 • 94 citations

The Intranuclear Movement of Balbiani Ring Premessenger Ribonucleoprotein Particles

1999 • 83 citations

The new paradigm: Integrating genomic function and nuclear architecture

1998 • 81 citations

Ultrastructural aspects of the ribonucleo-protein network in nuclei of walker tumor and rat liver

1967 • 81 citations

Genes and loops in 320,000 base-pairs of the Drosophila melanogaster chromosome

1986 • 81 citations

Autonomous splicing and complementation of in vivo-assembled spliceosomes.

1989 • 78 citations

Fractionation of the nuclear matrix. I. Partial separation into matrix protein fibrils and a residual ribonucleoprotein fraction.

1980 • 78 citations

Pre-mRNA Splicing and the Nuclear Matrix

1987 • 75 citations

The EAST protein of Drosophila controls an expandable nuclear endoskeleton

2000 • 74 citations

Association of RNA with the Cytoskeleton and the Nuclear Matrix

1986 • 74 citations

Induction of a Regular Nuclear Lattice by Overexpression of NuMA

1998 • 73 citations

Nuclear Matrix Proteins as Structural and Functional Components of the Mitotic Apparatus

1996 • 72 citations

Nuclear matrix and hnRNP share a common structural constituent associated with premessenger RNA.

1983 • 69 citations

Histone acetyltransferase is associated with the nuclear matrix.

1994 • 66 citations

Direct Visualization of a Protein Nuclear Architecture

1999 • 64 citations

Electron Tomography Reveals Posttranscriptional Binding of Pre-Mrnps to Specific Fibers in the Nucleoplasm

2000 • 63 citations

Active RNA polymerase I is fixed within the nucleus of HeLa cells.

1990 • 58 citations

Dynamic properties of the nuclear matrix

1979 • 58 citations

Fine Structural Specific Visualization of RNA on Ultrathin Sections

1998 • 57 citations

Ultrastructural Localization of Filamentous Actin within Neuronal Interphase Nuclei in Situ

1994 • 57 citations

Localization of heterogeneous nuclear ribonucleoprotein in the interphase nuclear matrix core filaments and on perichromosomal filaments at mitosis.

1991 • 56 citations

The Nuclear Matrix and the Regulation of Chromatin Organization and Function

1996 • 54 citations

The nuclear matrix prepared by amine modification

1999 • 54 citations

Two proteins that cycle asynchronously between centrosomes and nuclear structures: Drosophila CP60 and CP190

1997 • 52 citations

Fine structure and localization of the nuclear matrix in situ

1982 • 51 citations

Subnuclear partitioning and functional regulation of the Pit-1 transcription factor

1999 • 49 citations

Cytochalasin B selectively releases ovalbumin mRNA precursors but not the mature ovalbumin mRNA from hen oviduct nuclear matrix

1987 • 49 citations

Association of rapidly-labelled RNAs with actin in nuclear matrix from mouse L5178Y cells

1985 • 46 citations

Inhibition by quercetin and luteolin of chromosomal alterations induced by salted, deep-fried fish and mutton in rats

1996 • 45 citations

The release of 40S hnRNP particles by brief digestion of HeLa nuclei with micrococcal nuclease

1980 • 43 citations

HnRNP particles

1978 • 41 citations

Ultrastructural localization of active genes in nuclei of A431 cells

1996 • 41 citations

Targeting and Association of Proteins with Functional Domains in the Nucleus: The Insoluble Solution

1996 • 35 citations

Nuclear Matrix-like Filaments and Fibrogranular Complexes Form through the Rearrangement of Specific Nuclear Ribonucleoproteins

2000 • 33 citations

Nuclear matrix-bound DNA primase. Elucidation of an RNA priming system in nuclear matrix isolated from regenerating rat liver.

1987 • 30 citations

Relationship between the fine structural organization of chromatin and nucleic acid synthesis in regenerating rat hepatocytes

1981 • 24 citations

Purification and Characterization of Chicken Erythrocyte Histone Deacetylase 1

1999 • 22 citations

Enhanced processivity of nuclear matrix bound DNA polymerase .alpha. from regenerating rat liver

1987 • 21 citations

Effects of α-amanitine on chromatin in regenerating rat hepatocytes

1976 • 13 citations

Chromatin Structure and Nuclear Remodeling

1999 • 10 citations

Demonstration of a DNase-sensitive network associated with the nuclear pore complexes in rat liver nuclei

1999 • 7 citations

Chromosomal Nonhistone Proteins

2018 • 5 citations

Deleted Work

1955 • 0 citations