A Prospective Study of Alzheimer Disease in Down Syndrome

Amyloid plaque core protein in Alzheimer disease and Down syndrome.

1985 • 4,276 citations

Principles of Neurology

1977 • 1,759 citations

The Genetic Defect Causing Familial Alzheimer's Disease Maps on Chromosome 21

1987 • 1,149 citations

Occurrence of neuropathological changes and dementia of Alzheimer's disease in Down's syndrome

1985 • 1,125 citations

Senile dementia of the Alzheimer type

1983 • 835 citations

Alzheimer's disease: A study of epidemiological aspects

1984 • 529 citations

Heterogeneity in dementia of the Alzheimer type: Evidence of subgroups

1985 • 507 citations

Alzheimer's disease in Down's syndrome

1985 • 393 citations

Clinically diagnosed Alzheimer's disease: Autopsy results in 150 cases

1988 • 356 citations

The development of the pathologic changes of Alzheimer's disease and senile dementia in patients with Down's syndrome.

1973 • 340 citations

Seizures and myoclonus in patients with Alzheimer's disease

1986 • 325 citations

PRESENILE DEMENTIA AND ALZHEIMER'S DISEASE IN MONGOLISM

1969 • 292 citations

Alzheimer's disease: Genetic aspects and associated clinical disorders

1983 • 269 citations

Neuropathologic and clinical features of Parkinson's disease in Alzheimer's disease patients

1987 • 254 citations

Catecholamines and cholinergic enzymes in pre-senile and senile Alzheimer-type dementia and down's syndrome

1983 • 250 citations

EARLY SENILE DEMENTIA IN MONGOLOID IDIOCY

1948 • 221 citations

Presenile dementia in Down's syndrome

1974 • 219 citations

Down's syndrome

1984 • 191 citations

Relationship between plaques, tangles, and dementia in Down syndrome

1980 • 189 citations

LONGEVITY AND MORTALITY IN DOWN'S SYNDROME

1982 • 157 citations

Precocious aging and dementia in patients with Down's syndrome.

1978 • 154 citations

Extrapyramidal signs in Alzheimer's disease

1984 • 153 citations

Parkinson's Disease in Patients With Alzheimer's Disease

1986 • 144 citations

Neurofibrillary tangles, granulovacuolar degeneration, and neuron loss in down syndrome: Quantitative comparison with alzheimer dementia

1980 • 143 citations

The Extrapyramidal Disorder of Alzheimer’s Disease

1974 • 115 citations

Age-related neuropsychological deficits in Down's syndrome.

1984 • 93 citations

Prevalence of thyroid disorder in Down syndrome

1978 • 91 citations

Discrepancy between Alzheimer‐Type Neuropathology and Dementia in Persons with Down's Syndromea

1986 • 80 citations

THE PREVALENCE OF EPILEPSY AMONG MONGOLS RELATED TO AGE

1974 • 79 citations

CLINICAL EVALUATION OF DEMENTIA IN DOWN'S SYNDROME: A PRELIMINARY REPORT

1982 • 71 citations

Development of Alzheimer disease in Down syndrome individuals.

1983 • 62 citations

TOPOGRAPHY OF NEUROFIBRILLARY TANGLES AND GRANULOVACUOLES IN HIPPOCAMPI OF PATIENTS WITH DOWN'S SYNDROME: QUANTITATIVE COMPARISON WITH NORMAL AGEING AND ALZHEIMER'S DISEASE

1981 • 62 citations

Dementia in Down's syndrome: Observations from a neurology clinic

1982 • 59 citations

Clinical Expression of Alzheimer’s Disease in Down’s Syndrome

1986 • 57 citations

DEMENTIA IN AGEING MENTAL DEFECTIVES: A CLINICAL PSYCHIATRIC STUDY

1974 • 56 citations

Cerebral amyloid angiopathy in Down's syndrome.

1986 • 35 citations

Human Chromosome Abnormalities as Related to Physical and Mental Dysfunction

1969 • 25 citations

Alzheimer's disease in Down syndrome: clinical-neuropathological observations.

1969 • 23 citations

SKIN AGE IN DOWN'S SYNDROME: A NOTE ON THE FINDINGS OF MURDOCH AND EVANS

1978 • 11 citations