Diabetes-induced vascular dysfunction in the retina: role of endothelins

Endothelins: molecular biology, biochemistry, pharmacology, physiology, and pathophysiology.

1994 • 1,631 citations

Protein kinase C activation and the development of diabetic complications.

1998 • 1,328 citations

Hyperglycemic Pseudohypoxia and Diabetic Complications

1993 • 1,025 citations

Pharmacological characterization of bosentan, a new potent orally active nonpeptide endothelin receptor antagonist.

1994 • 650 citations

Endothelin: visualization of mRNAs by in situ hybridization provides evidence for local action.

1989 • 354 citations

Role of Blood Flow and Impaired Autoregulation in the Pathogenesis of Diabetic Retinopathy

1995 • 311 citations

Endothelins: multifunctional renal peptides.

1993 • 306 citations

THE CELLULAR AND MOLECULAR MECHANISMS OF DIABETIC COMPLICATIONS

1996 • 292 citations

Ocular blood flow and associated functional deviations in diabetic retinopathy

1999 • 224 citations

Doppler Ultrasonography of the Ophthalmic and Central Retinal Vessels

1991 • 218 citations

Vasoactive Peptides Modulate Vascular Endothelial Cell Growth Factor Production and Endothelial Cell Proliferation and Invasion

1997 • 205 citations

Advanced products of nonenzymatic glycosylation and the pathogenesis of diabetic vascular disease

1988 • 190 citations

The structure and specificity of endothelin receptors: Their importance in physiology and medicine

1993 • 182 citations

Expression of Endothelin-1, Endothelin-3, Endothelin-Converting Enzyme-1, and Endothelin-A and Endothelin-B Receptor mRNA After Angioplasty-Induced Neointimal Formation in the Rat

1996 • 146 citations

Effect of a Specific Endothelin Receptor A Antagonist on mRNA Levels for Extracellular Matrix Components and Growth Factors in Diabetic Glomeruli

1995 • 137 citations

Stimulatory Interaction Between Vascular Endothelial Growth Factor and Endothelin-1 on Each Gene Expression

1998 • 131 citations

The in vivo effect of endothelins on retinal circulation in nondiabetic and diabetic rats.

1995 • 94 citations

Role of blood flow and impaired autoregulation in the pathogenesis of diabetic retinopathy

1995 • 86 citations

Differential regulation of fos and jun gene expression and AP-1 cis-element activity by endothelin isopeptides. Possible implications for mitogenic signaling by endothelin.

1992 • 81 citations

Endothelin Receptor-Binding Subtypes in the Human Retina and Choroid

1994 • 79 citations

The potential contribution of endothelin-1 to neurovascular abnormalities in streptozotocin-diabetic rats

1994 • 68 citations

Endothelins as Cardiovascular Peptides

1996 • 67 citations

Augmented retinal endothelin-1, endothelin-3, endothelinA and endothelinB gene expression in chronic diabetes

1998 • 63 citations

Immunoreactive endothelin distribution in ocular tissues.

1994 • 62 citations

Early biosynthetic changes in the diabetic-like retinopathy of galactose-fed rats

1996 • 56 citations

Induction of resistance to endothelin-1's biochemical actions by elevated glucose levels in retinal pericytes

1992 • 50 citations

Color Doppler ultrasonography of the eye and orbit

1993 • 49 citations

Ocular arterial flow hemodynamics in patients with diabetes mellitus.

1998 • 49 citations

Endothelin-1 and endothelin-3-like immunoreactivity in the eyes of diabetic and non-diabetic BB/W rats

1997 • 47 citations

Expression of endothelin-3 mRNA along rat nephron segments using polymerase chain reaction

1993 • 45 citations

Early increase precedes a depletion of endothelin‐1 but not of von Willebrand factor in cutaneous microvessels of diabetic patients. A quantitative immunohistochemical study

1995 • 27 citations

Insulin-like growth factor-I expression is not increased in the retina of diabetic

1991 • 13 citations

The potential contribution of endothelin-1 to neurovascular abnormalities in streptozotocin-diabetic rats

1994 • 8 citations

Deleted Work

1955 • 0 citations