The RecA Protein: Structure and Functio

Distantly related sequences in the alpha- and beta-subunits of ATP synthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold.

1982 • 5,284 citations

Enzyme structure and mechanism

1977 • 2,935 citations

Prediction of the Secondary Structure of Proteins from their Amino Acid Sequence

1979 • 2,930 citations

Bacterial evolution.

1987 • 2,521 citations

Normal oxidative damage to mitochondrial and nuclear DNA is extensive.

1988 • 1,709 citations

The SOS regulatory system of Escherichia coli

1982 • 1,491 citations

Principles of protein structure

1980 • 1,094 citations

Principles of Protein Structure

1979 • 1,090 citations

ISOLATION AND CHARACTERIZATION OF RECOMBINATION-DEFICIENT MUTANTS OF ESCHERICHIA COLI K12

1965 • 819 citations

Evolution in bacteria: Evidence for a universal substitution rate in cellular genomes

1987 • 777 citations

PSORALENS AS PHOTOACTIVE PROBES OF NUCLEIC ACID STRUCTURE AND FUNCTION: ORGANIC CHEMISTRY, PHOTOCHEMISTRY, AND BIOCHEMISTRY

1985 • 749 citations

Mutagenesis and inducible responses to deoxyribonucleic acid damage in Escherichia coli.

1984 • 743 citations

INDUCIBLE DNA REPAIR SYSTEMS

1985 • 586 citations

Exchanges between DNA strands in ultraviolet-irradiated Escherichia coli

1971 • 582 citations

RECOMBINATION DEFICIENT MUTANTS OF E. COLI AND OTHER BACTERIA

1973 • 568 citations

The repair of double-strand breaks in the nuclear DNA of Saccharomyces cerevisiae and its genetic control

1976 • 518 citations

Autodigestion of lexA and phage lambda repressors.

1984 • 505 citations

Genetic analysis of the recF pathway to genetic recombination in Escherichia coli k12: Isolation and characterization of mutants

1973 • 479 citations

RecA-mediated cleavage activates UmuD for mutagenesis: mechanistic relationship between transcriptional derepression and posttranslational activation.

1988 • 415 citations

Purified Escherichia coli recA protein catalyzes homologous pairing of superhelical DNA and single-stranded fragments.

1979 • 377 citations

Role of RecA protein spiral filaments in genetic recombination

1984 • 362 citations

UmuD mutagenesis protein of Escherichia coli: overproduction, purification, and cleavage by RecA.

1988 • 354 citations

E. coli recA protein-directed cleavage of phage λ repressor requires polynucleotide

1980 • 352 citations

ENZYMES OF GENERAL RECOMBINATION

1987 • 333 citations

Studies of asymmetry in the three-dimensional structure of lobster D-glyceraldehyde-3-phosphate dehydrogenase.

1975 • 330 citations

Proteolytic cleavage of bacteriophage lambda repressor in induction.

1975 • 326 citations

Endogenous DNA damage as related to cancer and aging

1989 • 323 citations

recA protein of Escherichia coli promotes branch migration, a kinetically distinct phase of DNA strand exchange.

1981 • 312 citations

Interaction of recA protein with single-stranded DNA

1985 • 310 citations

ATP-dependent renaturation of DNA catalyzed by the recA protein of Escherichia coli.

1979 • 308 citations

Escherichia coli recA gene product inactivates phage lambda repressor.

1978 • 305 citations

Substrate positions and induced-fit in crystalline adenylate kinase

1977 • 304 citations

Sequences of the recA gene and protein.

1980 • 296 citations

Automatic generation of primary sequence patterns from sets of related protein sequences.

1990 • 292 citations

Genetic Recombination: Strand Transfer and Mismatch Repair

1978 • 270 citations

Studies of asymmetry in the three-dimensional structure of lobster D-glyceraldehyde-3-phosphate dehydrogenase

1975 • 267 citations

Organization of the recA gene of Escherichia coli.

1980 • 258 citations

Prophage induction and cell division in E. coli

1972 • 255 citations

Function of nucleoside triphosphate and polynucleotide in Escherichia coli recA protein-directed cleavage of phage lambda repressor.

1981 • 251 citations

Stable DNA heteroduplex formation catalyzed by the Escherichia coli RecA protein in the absence of ATP hydrolysis.

1990 • 249 citations

Binding of the recA protein of Escherichia coli to single- and double-stranded DNA.

1981 • 248 citations

Effects of Escherichia coli SSB protein on the single-stranded DNA-dependent ATPase activity of Escherichia coli RecA protein

1987 • 246 citations

Structure of helical RecA-DNA complexes

1986 • 244 citations

New recA mutations that dissociate the various RecA protein activities in Escherichia coli provide evidence for an additional role for RecA protein in UV mutagenesis

1989 • 235 citations

UmuC mutagenesis protein of Escherichia coli: purification and interaction with UmuD and UmuD'.

1989 • 222 citations

Nucleotide binding by membrane components of bacterial periplasmic binding protein-dependent transport systems.

1985 • 219 citations

The helicity of DNA in complexes with RecA protein

1982 • 217 citations

Characteristics of Purified recA Protein and the Regulation of Its Synthesis In Vivo

1979 • 212 citations

Characterization of complexes between recA protein and duplex DNA by electron microscopy

1982 • 212 citations

Directionality and polarity in recA protein-promoted branch migration.

1981 • 203 citations

Genetic Recombination

1987 • 200 citations

The direction of RecA protein assembly onto single strand DNA is the same as the direction of strand assimilation during strand exchange.

1985 • 198 citations

The Biology of Nonspecific DNA Protein Interactions

1990 • 195 citations

Genetic Damage, Mutation, and the Evolution of Sex

1985 • 192 citations

GENERAL MICROBIOLOGY OF recA: Environmental and Evolutionary Significance

1990 • 190 citations

Mechanisms of DNA replication and recombination

1984 • 187 citations

Homologous pairing in genetic recombination: complexes of recA protein and DNA.

1979 • 184 citations

Induction of SOS functions: Regulation of proteolytic activity of E. coil RecA protein by interaction with DNA and nucleoside triphosphate

1981 • 183 citations

Elongation of duplex DNA by recA protein

1981 • 180 citations

Identification of the recA ( tif ) gene product of Escherichia coli

1977 • 177 citations

Mutagenic repair in Escherichia coli: products of the recA gene and of the umuD and umuC genes act at different steps in UV-induced mutagenesis.

1985 • 166 citations

Prophage induction and filament formation in a mutant strain of Escherichia coli.

1967 • 159 citations

Polarity of heteroduplex formation promoted by Escherichia coli recA protein.

1981 • 159 citations

Recombination-deficient mutant of Streptococcus faecalis

1980 • 158 citations

A new cell division operon inEscherichia coli

1986 • 156 citations

Activity of the Escherichia coli recA-gene Product

1979 • 153 citations

Double-strand breaks stimulate alternative mechanisms of recombination repair

1989 • 153 citations

Mechanisms and consequences of DNA damage processing

1987 • 152 citations

Cloning of the recA gene of Neisseria gonorrhoeae and construction of gonococcal recA mutants

1987 • 150 citations

The topology of homologous pairing promoted by RecA protein

1980 • 146 citations

Insertions, deletions and mismatches in heteroduplex DNA made by recA protein

1983 • 145 citations

Models of specifically paired like (homologous) nucleic acid structures

1971 • 145 citations

Hydrolysis of nucleoside triphosphates catalyzed by the recA protein of Escherichia coli. Characterization of ATP hydrolysis.

1981 • 145 citations

Networks of DNA and RecA protein are intermediates in homologous pairing

1985 • 144 citations

Single strands induce recA protein to unwind duplex DNA for homologous pairing

1979 • 143 citations

Analysis and prediction of the packing of α-helices against a β-sheet in the tertiary structure of globular proteins

1982 • 141 citations

Stable binding of recA protein to duplex DNA. Unraveling a paradox.

1987 • 140 citations

Prophage induction and cell division in E. coli

1977 • 140 citations

Heteroduplex formation by recA protein: polarity of strand exchanges.

1981 • 138 citations

Capacity of RecA protein to bind preferentially to UV lesions and inhibit the editing subunit (epsilon) of DNA polymerase III: a possible mechanism for SOS-induced targeted mutagenesis.

1986 • 137 citations

Mechanism of transient inhibition of DNA synthesis in ultraviolet-irradiated E. coli: Inhibition is independent of recA whilst recovery requires RecA protein itself and an additional, inducible SOS function

1985 • 135 citations

Isolation and visualization of active presynaptic filaments of recA protein and single-stranded DNA.

1984 • 135 citations

Fate of Transforming Deoxyribonucleic Acid After Uptake by Competent Bacillus subtilis : Phenotypic Characterization of Radiation-Sensitive Recombination-Deficient Mutants

1973 • 135 citations

Purification and characterization of an activity from Saccharomyces cerevisiae that catalyzes homologous pairing and strand exchange.

1987 • 132 citations

Triplet information in helix prediction applied to the analysis of super-secondary structures

1977 • 131 citations

Purification of a RecA protein analogue from Bacillus subtilis.

1985 • 129 citations

Assembly and disassembly of RecA protein filaments occur at opposite filament ends. Relationship to DNA strand exchange.

1990 • 129 citations

Isolation and characterization of the recA gene of Rhizobium meliloti

1983 • 125 citations

Constitutive expression of SOS functions and modulation of mutagenesis resulting from resolution of genetic instability at or near the recA locus of Escherichia coli

1982 • 124 citations

Recognition of duplex DNA containing single-stranded regions by recA protein.

1980 • 122 citations

recA protein-promoted ATP hydrolysis occurs throughout recA nucleoprotein filaments.

1987 • 121 citations

General mechanism for RecA protein binding to duplex DNA

1988 • 121 citations

Visualization of RecA protein and its complexes with DNA by quick-freeze/deep-etch electron microscopy

1989 • 116 citations

Partial purification and characterization of a recombinase from human cells

1986 • 116 citations

Mutation induced by DNA damage: a many protein affair

1990 • 114 citations

Homologous pairing and topological linkage of DNA molecules by combined action of E. coli recA protein and topoisomerase I

1981 • 113 citations

Agonist-stimulated oscillations and cycling of intracellular free calcium in individual cultured muscle cells.

1988 • 105 citations

Nick-free formation of reciprocal heteroduplexes: a simple solution to the topological problem.

1979 • 104 citations

RecA protein self-assembly multiple discrete aggregation states

1988 • 103 citations

Functional domains of Escherichia coli recA protein deduced from the mutational sites in the gene

1984 • 103 citations

Fibers of RecA protein and complexes of RecA protein and single-stranded φX174 DNA as visualized by negative-stain electron microscopy

1986 • 103 citations

recA protein promotes homologous-pairing and strand-exchange reactions between duplex DNA molecules.

1981 • 99 citations

Binding stoichiometry and structure of RecA-DNA complexes studied by flow linear dichroism and fluorescence spectroscopy

1989 • 98 citations

Left-handed DNA. Cloning, characterization, and instability of inserts containing different lengths of (dC-dG) in Escherichia coli.

1982 • 98 citations

High-performance hydrophobic-interaction chromatography of proteins on a series of poly(alkyl aspart-amide)-silicas

1986 • 98 citations

Properties of a mutant recA-encoded protein reveal a possible role for Escherichia coli recF-encoded protein in genetic recombination.

1988 • 97 citations

Polar branch migration promoted by recA protein: effect of mismatched base pairs.

1982 • 97 citations

High salt activation of recA protein ATPase in the absence of DNA.

1988 • 96 citations

Characterization of lexB mutations in Escherichia coli K-12

1977 • 95 citations

Cloning of the Vibrio cholerae recA gene and construction of a Vibrio cholerae recA mutant

1986 • 92 citations

Topography of the interaction of recA protein with single-stranded deoxyoligonucleotides.

1986 • 92 citations

Recovery from ultraviolet light-induced inhibition of DNA synthesis requires umuDC gene products in recA718 mutant strains but not in recA+ strains of Escherichia coli.

1987 • 91 citations

Visualization of RecA-DNA Complexes Involved in Consecutive Stages of An In Vitro Strand Exchange Reaction

1984 • 91 citations

Exchange of recA protein between adjacent recA protein-single-stranded DNA complexes.

1986 • 91 citations

Characterization of the DNA binding activity of stable RecA-DNA complexes

1990 • 91 citations

Control of UV induction of recA protein.

1983 • 91 citations

The Location of DNA in RecA-DNA Helical Filaments

1989 • 89 citations

Helical RecA nucleoprotein filaments mediate homologous pairing and strand exchange

1989 • 88 citations

Differences in mutagenic and recombinational DNA repair in enterobacteria.

1985 • 86 citations

Cloning and characterization of recA genes froM Proteus vulgaris, Erwinia carotovora, Shigella flexneri, and Escherichia coli B/r

1984 • 84 citations

Dna Strand Exchange

1988 • 83 citations

The pairing activity of stable nucleoprotein filaments made from recA protein, single-stranded DNA, and adenosine 5'-(gamma-thio)triphosphate.

1985 • 82 citations

Separation of the presynaptic and synaptic phases of homologous pairing promoted by recA protein.

1984 • 82 citations

Mechanism of E. coli RecA protein directed strand exchanges in post-replication repair of DNA

1981 • 82 citations

Properties of the high-affinity single-stranded DNA binding state of the Escherichia coli recA protein

1988 • 80 citations

Isolation and properties of a recombination-deficient mutant of Micrococcus radiodurans

1975 • 80 citations

Construction of an Agrobacterium tumefaciens C58 recA mutant

1989 • 78 citations

The sequence and function of the recA gene and its protein in Pseudomonas aeruginosa PAO

1987 • 78 citations

Interaction of the recA protein of Escherichia coli with single-stranded DNA.

1985 • 78 citations

Sequence comparison of single-stranded DNA binding proteins and its structural implications

1987 • 78 citations

Two mutations that alter the regulatory activity of E. coli recA protein

1981 • 77 citations

Properties of the duplex DNA-dependent ATPase activity of Escherichia coli RecA protein and its role in branch migration.

1987 • 77 citations

Isolation and properties of recombination-deficient mutants of Pseudomonas aeruginosa

1974 • 77 citations

recA protein from Escherichia coli. A very rapid and simple purification procedure: binding of adenosine 5'-triphosphate and adenosine 5'-diphosphate by the homogeneous protein

1982 • 77 citations

The formation of paranemic and plectonemic joints between DNA molecules by the recA and single-stranded DNA-binding proteins of Escherichia coli.

1985 • 77 citations

On the role of single-stranded DNA binding protein in recA protein-promoted DNA strand exchange.

1983 • 76 citations

Left-handed Z-DNA binding by the recA protein of Escherichia coli.

1987 • 76 citations

Mismatch repair-induced meiotic recombination requires the pms1 gene product.

1990 • 76 citations

Electron microscopic visualization of the RecA protein-mediated pairing and branch migration phases of DNA strand exchange.

1987 • 74 citations

ADP-mediated dissociation of stable complexes of recA protein and single-stranded DNA.

1983 • 73 citations

recA protein binding to the heteroduplex product of DNA strand exchange.

1987 • 73 citations

On the mechanism of renaturation of complementary DNA strands by the recA protein of Escherichia coli.

1985 • 72 citations

Molecular cloning and characterization of the recA gene of Pseudomonas aeruginosa PAO

1985 • 72 citations

Structure of helical RecA-DNA complexes

1988 • 71 citations

Triple-helical DNA pairing intermediates formed by recA protein.

1990 • 71 citations

Dissociation pathway for recA nucleoprotein filaments formed on linear duplex DNA

1989 • 71 citations

A Large-Scale Preparation and Some Physicochemical Properties of RecA Protein

1981 • 70 citations

Expression of Serratia marcescens extracellular proteins requires recA

1990 • 70 citations

3' homologous free ends are required for stable joint molecule formation by the RecA and single-stranded binding proteins of Escherichia coli.

1987 • 70 citations

RecA protein and SOS

1987 • 69 citations

Location of functional regions of the Escherichia coli RecA protein by DNA sequence analysis of RecA protease-constitutive mutants

1986 • 69 citations

Homology-dependent changes in adenosine 5'-triphosphate hydrolysis during recA protein-promoted DNA strand exchange: evidence for long paranemic complexes

1987 • 68 citations

Plaque color method for rapid isolation of novel recA mutants of Escherichia coli K-12: new classes of protease-constitutive recA mutants

1985 • 67 citations

Inviability of dam recA and dam recB cells of Escherichia coli is correlated with their inability to repair DNA double-strand breaks produced by mismatch repair

1986 • 67 citations

Purification and characterization of a protein from human cells which promotes homologous pairing of DNA.

1990 • 65 citations

Light scattering studies of the recA protein of Escherichia coli: relationship between free recA filaments and the recA.cntdot.ssDNA complex

1985 • 65 citations

Sequence of the T4 recombination gene,uvsX, and its comparison with that of therecAgene ofEscherichia coil

1985 • 65 citations

Interaction of the recA protein of Escherichia coli with adenosine 5'-O-(3-thiotriphosphate).

1981 • 65 citations

recA‐dependent DNA repair processes

1989 • 65 citations

RecA Protein self-assembly

1990 • 64 citations

Enhancement of Escherichia coli recA protein enzymic function by dATP

1989 • 64 citations

recA is required in the induction of pectin lyase and carotovoricin in Erwinia carotovora subsp. carotovora

1985 • 64 citations

Inhibition of RecA protein promoted ATP hydrolysis. 1. ATP.gamma.S and ADP are antagonistic inhibitors

1990 • 64 citations

Cloned truncated recA genes in E. coli

1982 • 62 citations

Ionic inhibition of formation of RecA nucleoprotein networks blocks homologous pairing.

1985 • 62 citations

Prophage ψ80 is induced in Escherichia coli K12 recA430

1983 • 62 citations

Increase of the DNA strand assimilation activity of recA protein by removal of the C terminus and structure-function studies of the resulting protein fragment.

1988 • 62 citations

Nucleotide sequence and further characterization of the Synechococcus sp. strain PCC 7002 recA gene: complementation of a cyanobacterial recA mutation by the Escherichia coli recA gene

1990 • 62 citations

Extent of duplex DNA underwinding induced by RecA protein binding in the presence of ATP

1989 • 62 citations

Recombination-deficient mutants of Bacillus subtilis

1976 • 61 citations

Tyrosine 264 in the recA protein from Escherichia coli is the site of modification by the photoaffinity label 8-azidoadenosine 5'-triphosphate.

1985 • 61 citations

The preference for a 3' homologous end is intrinsic to RecA-promoted strand exchange.

1990 • 58 citations

Recombinational bypass of pyrimidine dimers promoted by the recA protein of Escherichia coli.

1982 • 58 citations

Postreplicational formation and repair of DNA double-strand breaks in UV-irradiated Escherichia coli uvrB cells

1986 • 56 citations

The mechanism of homologous DNA strand exchange catalyzed by the bacteriophage T4 uvsX and gene 32 proteins.

1988 • 55 citations

Effect of rec mutations on the ultraviolet protecting and mutation-enhancing properties of the plasmid R-Utrecht in Salmonella typhimurium

1973 • 55 citations

Cloning of the Bacillus subtilis recE+ gene and functional expression of recE+ in B. subtilis

1988 • 54 citations

Interaction of RecA protein with a photoaffinity analog of ATP, 8-azido-ATP: determination of nucleotide cofactor binding parameters and of the relationship between ATP binding and ATP hydrolysis

1986 • 54 citations

Analysis of DNA-RecA protein interactions involving the protein self-association reaction

1989 • 54 citations

Characterization of an ATP-dependent DNA strand transferase from human cells.

1987 • 54 citations

Left-Handed Z-DNA and Genetic Recombination

1989 • 54 citations

Role of SSB protein in RecA promoted branch migration reactions

1982 • 54 citations

Structure of helical RecA-DNA complexes

1988 • 52 citations

FLUORESCENT NUCLEOSIDES AND NUCLEOTIDES^*

1975 • 52 citations

Studies of the interaction of RecA protein with DNA

1983 • 52 citations

Patterns of nuclease protection during strand exchange. recA protein forms heteroduplex DNA by binding to strands of the same polarity.

1986 • 51 citations

Visualization of the paranemic joining of homologous DNA molecules catalyzed by the RecA protein of Escherichia coli.

1986 • 50 citations

Inhibition of RecA protein promoted ATP hydrolysis. 2. Longitudinal assembly and disassembly of RecA protein filaments mediated by ATP and ADP

1990 • 50 citations

KIN, a mammalian nuclear protein immunoglifically related to E. coil RecA protein

1989 • 50 citations

Mutants of Escherichia coli K12 (λ)+ non-inducible by thymine deprivation

1970 • 49 citations

Translocation of Escherichia coli recA protein from a single-stranded tail to contiguous duplex DNA.

1987 • 49 citations

Purification and Characterization of a DNA-pairing and Strand Transfer Activity from Mitotic Saccharomyces cerevisiae

1989 • 49 citations

Lack of DNA homology in a pair of divergent chromosomes greatly sensitizes them to loss by DNA damage.

1989 • 49 citations

General recombination: Functions and structure of RecA protein

1986 • 49 citations

Molecular cloning and characterization of the recA gene from the cyanobacterium Synechococcus sp. strain PCC 7002

1987 • 49 citations

Reversibility of strand invasion promoted by recA protein and its inhibition by Escherichia coli single-stranded DNA-binding protein or phage T4 gene 32 protein.

1988 • 48 citations

Germ line recombination may be primarily a manifestation of DNA repair processes

1977 • 48 citations

Purification and characterization of recA protein from salmonella typhimurium.

1983 • 48 citations

The accessibility of DNA to dimethylsulfate in complexes with recA protein.

1987 • 48 citations

Investigation of RecA-polynucleotide interactions from the measurement of LexA repressor cleavage kinetics. Presence of different types of complex

1989 • 48 citations

Underwinding of DNA associated with duplex-duplex pairing by RecA protein.

1990 • 48 citations

Biochemical basis of the temperature-inducible constitutive protease activity of the recA441 protein of Escherichia coli

1988 • 48 citations

Stoichiometry, base orientation, and nuclease accessibility of RecA.DNA complexes seen by polarized light in flow-oriented solution. Implications for the mechanism of genetic recombination.

1990 • 48 citations

On RecA protein-mediated homologous alignment of two DNA molecules. Three strands versus four strands.

1990 • 47 citations

Duplex-duplex interactions catalyzed by recA protein allow strand exchanges to pass double-strand breaks in DNA

1984 • 47 citations

Mechanistic aspects of the DNA strand exchange activity of E. coli recA protein

1987 • 47 citations

Construction of a recombinase-deficient mutant recA protein that retains single-stranded DNA-dependent ATPase activity.

1988 • 47 citations

Isolation of altered recA polypeptides and interaction with ATP and DNA.

1985 • 47 citations

Transfer of recA protein from one polynucleotide to another. Kinetic evidence for a ternary intermediate during the transfer reaction.

1987 • 46 citations

Image analysis reveals that Escherichia coli RecA protein consists of two domains

1990 • 46 citations

RecA independent recombination of poly[d(GT)-d(CA)] in pBR322

1986 • 46 citations

Homologous pairing can occur before DNA strand separation in general genetic recombination

1981 • 46 citations

Homologous pairing and the formation of nascent synaptic intermediates between regions of duplex DNA by RecA protein

1989 • 45 citations

Complementation pattern of lexB and recA mutations in Escherichia coli K12; mapping of tif-1, lexB and recA mutations

1977 • 45 citations

Isolation and characterization of specialized transducing bacteriophages for the recA gene of Escherichia coli

1977 • 44 citations

The mechanics of winding and unwinding helices in recombination: Torsional stress associated with strand transfer promoted by RecA protein

1988 • 44 citations

Modulation of the SOS response by truncated RecA proteins

1989 • 43 citations

"Activated"-RecA protein affinity chromatography of LexA repressor and other SOS-regulated proteins.

1989 • 43 citations

Regulation of expression and nucleotide sequence of the Anabaena variabilis recA gene

1989 • 42 citations

recA-Dependent DNA repair in UV-irradiated Escherichia coli

1987 • 42 citations

Isolation of protease-proficient, recombinase-deficient recA mutants of Escherichia coli K-12

1985 • 41 citations

Purification and properties of the recA protein of Proteus mirabilis. Comparison with Escherichia coli recA protein; specificity of interaction with single strand binding protein.

1983 • 41 citations

Interspecies recA protein substitution in Escherichia coli and Proteus mirabilis

1982 • 41 citations

RecA protein reinitiates strand exchange on isolated protein-free DNA intermediates

1990 • 40 citations

Evidence for nucleotide-mediated changes in the domain structure of the RecA protein of Escherichia coli

1987 • 40 citations

Identification of the amino acid substitutions in two mutant forms of the recA protein from Escherichia coli: recA441 and recA629.

1984 • 40 citations

Effect of host lex, recA, recF, and uvrD genotypes on the ultraviolet light-protecting and related properties of plasmid R46 in Escherichia coli

1979 • 40 citations

Nucleotide sequence and expression of a cloned Thiobacillus ferrooxidans recA gene in Escherichia coli

1989 • 40 citations

tif-1 mutation alters polynucleotide recognition by the recA protein of Escherichia coli.

1981 • 39 citations

Characterization of the Pseudomonas aeruginosa recA analog and its protein product: rec-102 is a mutant allele of the P. aeruginosa PAO recA gene

1987 • 38 citations

The distribution of Escherichia coli recA protein bound to duplex DNA with single-stranded ends.

1987 • 37 citations

Cysteinyl residues of Escherichia coli recA protein

1984 • 37 citations

Affinity labeling of a tyrosine residue in the ATP binding site of the recA protein from Escherichia coli with 5'-p-fluorosulfonylbenzoyladenosine.

1985 • 37 citations

Cloned truncated recA genes in E. coli

1982 • 37 citations

The nucleotide sequence of the recE⁺gene of Bacillus subtilis

1990 • 37 citations

Chemistry, biology, and clinical uses of nucleoside analogs

1975 • 37 citations

Covalent modification of the recA protein from Escherichia coli with the photoaffinity label 8-azidoadenosine 5'-triphosphate.

1985 • 37 citations

RecA protein-promoted cleavage of LexA repressor in the presence of ADP and structural analogues of inorganic phosphate, the fluoride complexes of aluminum and beryllium

1989 • 36 citations

Construction of recombination-deficient strains of Pseudomonas aeruginosa

1983 • 35 citations

Structure of a RecA-DNA complex from linear dichroism and small-angle neutron-scattering in flow-oriented solution

1990 • 35 citations

Co-operativity value of DNA-RecA protein interaction

1986 • 34 citations

Linear dichroism study of RecA-DNA complexes. Structural evidence and binding stoichiometries.

1987 • 34 citations

Molecular cloning of a recA-like gene from the cyanobacterium Anabaena variabilis

1987 • 34 citations

Cloning and expression in Escherichia coli of a recA-like gene from Bacteroides fragilis

1987 • 34 citations

Activation of protease-constitutive recA proteins of Escherichia coli by rRNA and tRNA

1988 • 34 citations

Treadmilling of tubulin and actin

1982 • 34 citations

Absence of repair of photodynamically induced damage in two mutants of Proteus mirabilis with increased sensitivity to monofunctional alkylating agents

1968 • 33 citations

Similarity in properties and mapping of three Rec mutants of Haemophilus influenzae

1976 • 33 citations

Homology-dependent underwinding of duplex DNA in RecA protein generated paranemic complexes

1988 • 33 citations

tif-dependent induction of colicin E1, prophage lambda, and filamentation in Escherichia coli K-12

1980 • 33 citations

Kinetic analysis of the pre-equilibrium steps in the self-assembly of RecA protein from Escherichia coli.

1990 • 32 citations

DNA and Nucleoside Triphosphate Binding Properties of recA Protein from Escherichia coli

1981 • 32 citations

Biochemical events essential to the recombination activity of Escherichia coli RecA protein

1989 • 32 citations

Kinetics of DNA renaturation catalyzed by RecA protein of Escherichia coli

1985 • 32 citations

The structure of recA protein-DNA filaments. 2 recA protein monomers unwind 17 base pairs of DNA by 11.5 degrees/base pair in the presence of adenosine 5'-O-(3-thiotriphosphate).

1983 • 31 citations

DNase protection by recA protein during strand exchange. Asymmetric protection of the Holliday structure.

1988 • 31 citations

Efficiency of induction of prophage lambda mutants as a function of recA alleles

1985 • 30 citations

lexB: A New Gene Governing Radiation Sensitivity and Lysogenic Induction in Escherichia coli K12

1975 • 30 citations

Activation of protease-constitutive recA proteins of Escherichia coli by all of the common nucleoside triphosphates

1988 • 30 citations

Cloning of a recA-like gene of Proteus mirabilis

1981 • 29 citations

Nucleotide binding by a 24-residue peptide from the RecA protein of Escherichia coli.

1986 • 28 citations

An alpha-helical peptide model for electrostatic interactions of proteins with DNA

1989 • 28 citations

Constitutive expression of the SOS response in recA718 mutants of Escherichia coli requires amplification of RecA718 protein

1987 • 27 citations

DNA sequence analysis of therecA genes fromProteus vulgaris, Erwinia carotovora, Shigella flexneri andEscherichia coli B/r

1990 • 27 citations

Evidence that the recA441 (tif-1) mutant of Escherichia coli K-12 contains a thermosensitive intragenic suppressor of RecA constitutive protease activity

1985 • 27 citations

Molecular cloning and biological characterization of the recA gene from Pseudomonas syringae

1987 • 27 citations

DNA Replication and Recombination

1964 • 26 citations

Recombinational Repair May Be an Important Function of Sexual Reproduction

1983 • 25 citations

Enhanced recA Protein Binding to Z DNA Represents a Kinetic Perturbation of a General Duplex DNA Binding Pathway

1989 • 24 citations

ATP-stimulated hydrolysis of GTP by recA protein: Kinetic consequences of cooperative recA protein-ATP interactions

1988 • 24 citations

Negative complementation of recA protein by recA1 polypeptide: in vivo recombination requires a multimeric form of recA protein

1984 • 24 citations

Nucleotide sequence of the recA gene ofProteus mirabilis

1989 • 23 citations

A model for the recA-dependent repair of excision gaps in UV-irradiated Escherichia coli

1987 • 22 citations

Characterization of the rec-1 gene of Haemophilus influenzae and behavior of the gene in Escherichia coli

1988 • 22 citations

Mutations at the Cysteine Codons of therecAGene ofEscherichia coli

1988 • 21 citations

Isolation of the rec Mutants in Staphylococcus aureus

1972 • 21 citations

Cloning and expression in Escherichia coli of a recA-like gene from Vibrio cholerae

1986 • 20 citations

Isolation and characterization of the Vibrio cholerae recA gene

1986 • 20 citations

Direct ATP photolabeling of Escherichia coli RecA proteins: identification of regions required for ATP binding

1986 • 20 citations

Affinity chromatography of RecA protein and RecA nucleoprotein complexes on RecA protein-agarose columns.

1988 • 19 citations

RecA protein — promoted λ repressor cleavage: complementation between RecA441 and RecA430 proteins in vitro

1984 • 19 citations

DNA sequence dependence of ATP hydrolysis by RecA protein

1988 • 19 citations

Specialized transduction of recA by bacteriophage lambda

1976 • 19 citations

Types of Recombination: Common Problems and Common Strategies

1984 • 19 citations

Temperature-sensitive recA mutant of Escherichia coli K-12: deoxyribonucleic acid metabolism after ultraviolet irradiation

1975 • 18 citations

Molecular Mechanisms of General Genetic Recombination: The DNA-binding Sites of RecA Protein

1984 • 18 citations

ATP-independent renaturation of complementary DNA strands by the mutant recA1 protein from Escherichia coli.

1986 • 18 citations

Molecular Cloning and Isolation of a Cyanobacterial Gene Which Increases the UV and Methyl Methanesulphonate Survival of recA Strains of Escherichia coli K12

1987 • 18 citations

Isolation of a recombination-deficient mutant of Rhodopseudomonas capsulata

1984 • 18 citations

Molecular cloning of the recA analog from the marine fish pathogen Vibrio anguillarum 775

1989 • 18 citations

Restoration of RecA protein activity by genetic complementation

1984 • 18 citations

Binding of RecA Protein to Z-form DNA Studied with Circular and Linear Dichroism Spectroscopy

1989 • 18 citations

Nucleotide sequence ofrecAgene ofAquaspirillum magnetotacticum

1990 • 18 citations

Cloning and Expression in Escherichia coli of a rec A-like Gene from the Acidophilic Autotroph Thiobacillus ferrooxidans

1988 • 17 citations

Cloning and characterization of the Aeromonas caviae recA gene and construction of an A. caviae recA mutant

1988 • 17 citations

Defective complex formation between single‐stranded DNA and mutant recA430 or recA1 protein of Escherichia coli

1983 • 17 citations

Interaction of RecA protein with pBR322 DNA modified by N-hydroxy-2-acetylaminofluorene and 4-hydroxyaminoquinoline 1-oxide

1990 • 16 citations

Kinetic modeling of the RecA protein promoted renaturation of complementary DNA strands

1989 • 16 citations

Molecular cloning of a recA-like gene of Methylophilus methylotrophus and identification of its product

1986 • 16 citations

Direct visualization of RecA protein binding to and unwinding duplex DNA following the D-loop cycle.

1988 • 16 citations

Cloning and characterization of the recA gene of Aquaspirillum magnetotacticum

1989 • 16 citations

Cloning and characterisation of the recA gene of Agrobacterium tumefaciens C58

1986 • 15 citations

A Model for the Core Structure of the Escherichia coli RecA Protein

1984 • 15 citations

Transfer of a plasmid mediating antibiotic resistance between strains of Streptococcus pyogenes in mixed cultures

1975 • 12 citations

Molecular Cloning and Expression in Escherichia coli of the recA Gene of Legionella pneumophila

1989 • 12 citations

Conservation of an ATP-binding domain among RecA proteins from Proteus vulgaris, Erwinia carotovora, Shigella flexneri, and Escherichia coli K-12 and B/r

1988 • 12 citations

Epitopes and active sites of the RecA protein.

1990 • 11 citations

Transfer of a plasmid mediating antibiotic resistance between strains ofStreptococcus pyogenes in mixed cultures

1975 • 11 citations

Primary structure analysis of the mutant recA 441 and recA 430 proteins.

1983 • 9 citations

RecA protein-DNA interactions in recombination

1987 • 8 citations

Isolation and characterization of a recA mutant of Erwinia chrysanthemi B374

1985 • 8 citations

Chromosomal mobilization from a recA mutant of Pseudomonas putida

1979 • 8 citations

[Cloning and characteristics of recA gene in Pseudomonas aeruginosa].

1986 • 8 citations

Transfer of recA Protein from One Polynucleotide to Another

1987 • 7 citations

REC A PROTEIN OF E. COLI PROMOTES HOMOLOGOUS PAIRING OF DNA MOLECULES BY A NOVEL MECHANISM

1980 • 7 citations

Binding of recA protein to single- and double-stranded polynucleotides occurs without involvement of its aromatic residues in stacking interactions with nucleotide bases

1988 • 5 citations

Cloning of the Serratia marcescens recA Gene and Construction of a Serratia marcescens recA Mutant

1989 • 5 citations

The Role of RecA Protein in Homologous Genetic Recombination

1989 • 3 citations

Functional characteristics of the recA gene from Serratia marcescens strain Sb

1991 • 2 citations

[Cloning and study of the function of recA-like gene of Yersinia pestis in Escherichia coli cells].

1989 • 1 citations

Deleted Work

1955 • 0 citations