5-Hydroxytryptamine 2B receptor regulates cell-cycle progression: Cross-talk with tyrosine kinase pathways

PD 098059 Is a Specific Inhibitor of the Activation of Mitogen-activated Protein Kinase Kinase in Vitro and in Vivo

1995 • 3,456 citations

CELLULAR FUNCTIONS REGULATED BY SRC FAMILY KINASES

1997 • 2,470 citations

Discovery of a Novel, Potent, and Src Family-selective Tyrosine Kinase Inhibitor

1996 • 1,946 citations

Role of transactivation of the EGF receptor in signalling by G-protein-coupled receptors

1996 • 1,473 citations

Cyclin D1 Expression Is Regulated Positively by the p42/p44 and Negatively by the p38/HOG Pathway

1996 • 1,203 citations

A role for Pyk2 and Src in linking G-protein-coupled receptors with MAP kinase activation

1996 • 971 citations

Src family kinases are required for integrin but not PDGFR signal transduction

1999 • 733 citations

Role of c-Src Tyrosine Kinase in G Protein-coupled Receptorand Gβγ Subunit-mediated Activation of Mitogen-activated Protein Kinases

1996 • 524 citations

Estrogen-induced Activation of Cdk4 and Cdk2 during G1-S Phase Progression Is Accompanied by Increased Cyclin D1 Expression and Decreased Cyclin-dependent Kinase Inhibitor Association with Cyclin E-Cdk2

1997 • 438 citations

Ras signalling linked to the cell-cycle machinery by the retinoblastoma protein

1997 • 359 citations

Convergence of Angiotensin II and Platelet-derived Growth Factor Receptor Signaling Cascades in Vascular Smooth Muscle Cells

1995 • 288 citations

c-Cbl is downstream of c-Src in a signalling pathway necessary for bone resorption

1996 • 285 citations

Estrogen-Dependent Cyclin E-cdk2 Activation through p21 Redistribution

1997 • 277 citations

Serotonin stimulates DNA synthesis in fibroblasts acting through 5–HT1B receptors coupled to a Gi-protein

1988 • 277 citations

Requirement of MAP kinase for differentiation of fibroblasts to adipocytes, for insulin activation of p90 S6 kinase and for insulin or serum stimulation of DNA synthesis.

1995 • 269 citations

Pleiotropic Coupling of G Protein-coupled Receptors to the Mitogen-activated Protein Kinase Cascade

1999 • 259 citations

Tyrphostins. 5. Potent Inhibitors of Platelet-Derived Growth Factor Receptor Tyrosine Kinase: Structure−Activity Relationships in Quinoxalines, Quinolines, and Indole Tyrphostins

1996 • 225 citations

Serotonin receptor subtypes : basic and clinical aspects

1991 • 217 citations

Molecular Biology of Serotonin Receptors

1991 • 200 citations

Receptor Ligand-Facilitated Gene Transfer: Enhancement of Liposome-Mediated Gene Transfer and Expression by Transferrin

1996 • 167 citations

Ligand-independent activation of platelet-derived growth factor receptor is a necessary intermediate in lysophosphatidic, acid-stimulated mitogenic activity in L cells

1998 • 154 citations

A synthetic peptide derived from p34cdc2 is a specific and efficient substrate of src-family tyrosine kinases.

1992 • 151 citations

Thrombin Stimulates Phosphorylation of Insulin-like Growth Factor-1 Receptor, Insulin Receptor Substrate-1, and Phospholipase C-γ1 in Rat Aortic Smooth Muscle Cells

1995 • 143 citations

Angiotensin II Activation of Cyclin D1-dependent Kinase Activity

1996 • 139 citations

Angiotensin II Controls p21 Activity via pp60

1996 • 138 citations

Ras Involvement in Signal Transduction by the Serotonin 5-HT2B Receptor

1996 • 132 citations

Ras-Dependent Activation of Fibroblast Mitogen-Activated Protein Kinase by 5-HT_1A Receptor via a G Protein βγ-Subunit-Initiated Pathway

1996 • 99 citations

Integration of mitogen-activated protein kinase kinase activation in vascular 5-hydroxytryptamine2A receptor signal transduction.

1998 • 80 citations

Endothelin-1 Is a Potent Survival Factor for c-Myc-Dependent Apoptosis

1998 • 73 citations

Inhibition of the MAP kinase cascade blocks heregulin-induced cell cycle progression in T-47D human breast cancer cells

1998 • 66 citations

Functional serotonin-2B receptors are expressed by a teratocarcinoma-derived cell line during serotoninergic differentiation.

1995 • 66 citations

An anchorage-dependent signal distinct from p42/44 MAP kinase activation is required for cell cycle progression

1998 • 48 citations

Suppression of Phospholipase C β, γ, and δ Families Alters Cell Growth and Phosphatidylinositol 4,5-Bisphosphate Levels

1997 • 37 citations

Functional co-operation between the subunits in heterodimeric platelet-derived growth factor receptor complexes

1999 • 21 citations

Differential regulation of fyn-associated protein tyrosine kinase activity by macrophage colony-stimulating factor (M-CSF) and granulocyte-macrophage colony-stimulating factor (GM-CSF)

1995 • 16 citations