Human fetal radial glia cells generate oligodendrocytes in vitro

A glial progenitor cell that develops in vitro into an astrocyte or an oligodendrocyte depending on culture medium

1983 • 2,009 citations

Neurons derived from radial glial cells establish radial units in neocortex

2001 • 1,932 citations

Cortical Excitatory Neurons and Glia, But Not GABAergic Neurons, Are Produced in the Emx1-Expressing Lineage

2002 • 1,351 citations

Isolation of radial glial cells by fluorescent-activated cell sorting reveals a neuronal lineage

2000 • 1,108 citations

Competing waves of oligodendrocytes in the forebrain and postnatal elimination of an embryonic lineage

2005 • 1,087 citations

Origin of Oligodendrocytes in the Subventricular Zone of the Adult Brain

2006 • 916 citations

Late Oligodendrocyte Progenitors Coincide with the Developmental Window of Vulnerability for Human Perinatal White Matter Injury

2001 • 909 citations

Asymmetric Inheritance of Radial Glial Fibers by Cortical Neurons

2001 • 871 citations

Sonic Hedgehog–Regulated Oligodendrocyte Lineage Genes Encoding bHLH Proteins in the Mammalian Central Nervous System

2000 • 839 citations

The oligodendrocyte and its many cellular processes

1993 • 837 citations

Identification of a Novel Family of Oligodendrocyte Lineage-Specific Basic Helix–Loop–Helix Transcription Factors

2000 • 786 citations

Both oligodendrocytes and astrocytes develop from progenitors in the subventricular zone of postnatal rat forebrain

1993 • 714 citations

Neuronal or Glial Progeny

2003 • 706 citations

Inductive interactions direct early regionalization of the mouse forebrain

1997 • 651 citations

A singularity of PDGF alpha-receptor expression in the dorsoventral axis of the neural tube may define the origin of the oligodendrocyte lineage

1993 • 497 citations

Vimentin, the 57 000 molecular weight protein of fibroblast filaments, is the major cytoskeletal component in immature glia.

1981 • 441 citations

Glial specification in the vertebrate neural tube

2004 • 412 citations

Glial cell lineage in the cerebral cortex: A review and synthesis

1991 • 407 citations

Coexistence of neuronal and glial precursor cells in the cerebral ventricular zone of the fetal monkey: an ultrastructural immunoperoxidase analysis

1981 • 397 citations

Dynamic expression of basic helix-loop-helix Olig family members: implication of Olig2 in neuron and oligodendrocyte differentiation and identification of a new member, Olig3

2000 • 376 citations

Oligodendrocyte wars

2005 • 348 citations

Generation of Oligodendrocyte Precursor Cells from Mouse Dorsal Spinal Cord Independent of Nkx6 Regulation and Shh Signaling

2005 • 325 citations

Hedgehog-dependent oligodendrocyte lineage specification in the telencephalon

2001 • 325 citations

Multiple Dorsoventral Origins of Oligodendrocyte Generation in the Spinal Cord and Hindbrain

2005 • 318 citations

A tripotential glial precursor cell is present in the developing spinal cord

1998 • 311 citations

The Whereabouts of a Morphogen: Direct Evidence for Short- and Graded Long-Range Activity of Hedgehog Signaling Peptides

2001 • 288 citations

Sonic hedgehog contributes to oligodendrocyte specification in the mammalian forebrain

2001 • 284 citations

Determination of Neuroepithelial Cell Fate: Induction of the Oligodendrocyte Lineage by Ventral Midline Cells and Sonic Hedgehog

1996 • 279 citations

Sonic hedgehog signaling is required during the appearance of spinal cord oligodendrocyte precursors

1999 • 266 citations

Contributions of cortical subventricular zone to the development of the human cerebral cortex

2005 • 261 citations

Sonic hedgehog in CNS development: one signal, multiple outputs

2002 • 259 citations

A subset of oligodendrocytes generated from radial glia in the dorsal spinal cord

2005 • 254 citations

Proliferation and differentiation potential of rat forebrain oligodendroglial progenitors both in vitro and in vivo

1991 • 249 citations

More Surprises in the Hedgehog Signaling Pathway

2000 • 219 citations

GFAP-positive progenitor cells produce neurons and oligodendrocytes throughout the CNS

2006 • 211 citations

Multipotent Stem Cells from the Mouse Basal Forebrain Contribute GABAergic Neurons and Oligodendrocytes to the Cerebral Cortex during Embryogenesis

2001 • 207 citations

Human Neural Stem Cells: Isolation, Expansion and Transplantation

1999 • 203 citations

Receptor-mediated endocytosis of soluble and membrane-tethered Sonic hedgehog by Patched-1

2000 • 195 citations

Oligodendrocyte lineage and the motor neuron connection

2000 • 189 citations

Sonic hedgehog maintains the identity of cortical interneuron progenitors in the ventral telencephalon

2005 • 183 citations

An ‘oligarchy’ rules neural development

2002 • 176 citations

Human oligodendrocytes derived from embryonic stem cells: Effect of noggin on phenotypic differentiation in vitro and on myelination in vivo

2006 • 174 citations

Dorsal Radial Glia Generate Olfactory Bulb Interneurons in the Postnatal Murine Brain

2007 • 153 citations

Cooperation between sonic hedgehog and fibroblast growth factor/MAPK signalling pathways in neocortical precursors

2004 • 135 citations

FGF-dependent generation of oligodendrocytes by a hedgehog-independent pathway

2003 • 125 citations

Olig Transcription Factors Are Expressed in Oligodendrocyte and Neuronal Cells in Human Fetal CNS

2005 • 125 citations

Sequence of oligodendrocyte development in the human fetal telencephalon

2004 • 123 citations

The Tripotential Glial-Restricted Precursor (GRP) Cell and Glial Development in the Spinal Cord: Generation of Bipotential Oligodendrocyte-Type-2 Astrocyte Progenitor Cells and Dorsal–Ventral Differences in GRP Cell Function

2002 • 122 citations

Sonic hedgehog-dependent emergence of oligodendrocytes in the telencephalon: evidence for a source of oligodendrocytes in the olfactory bulb that is independent of PDGFRα signaling

2001 • 113 citations

Early oligodendrocyte progenitor cells in the human fetal telencephalon

2002 • 113 citations

Specific characteristic of radial glia in the human fetal telencephalon

2004 • 112 citations

SubpallialDlx2-Expressing Cells Give Rise to Astrocytes and Oligodendrocytes in the Cerebral Cortex and White Matter

2002 • 112 citations

Human Cortical Neurons Originate from Radial Glia and Neuron-Restricted Progenitors

2007 • 102 citations

Characterization of A2B5⁺ glial precursor cells from cryopreserved human fetal brain progenitor cells

2002 • 100 citations

A Critical Role for Dorsal Progenitors in Cortical Myelination

2006 • 94 citations

Human oligodendrocyte precursor cells in vitro: Phenotypic analysis and differential response to growth factors

2003 • 90 citations

Origin of Oligodendrocytes within the Human Spinal Cord

1996 • 88 citations

Emergence of oligodendrocytes from human neural spheres

1997 • 87 citations

Radial Glia Cells in the Developing Human Brain

2007 • 86 citations

Cortical progenitor cells in the developing human telencephalon

2005 • 83 citations

Tracing human oligodendroglial development in vitro

2000 • 78 citations

Is Pax6 Critical for Neurogenesis in the Human Fetal Brain?

2007 • 76 citations

Early development and composition of the human primordial plexiform layer: An immunohistochemical study

1999 • 75 citations

Evidence for a second wave of oligodendrogenesis in the postnatal cerebral cortex of the mouse

2003 • 75 citations

Down-regulation of the axonal polysialic acid–neural cell adhesion molecule expression coincides with the onset of myelination in the human fetal forebrain

2007 • 72 citations

Oligodendroglial development in human fetal cerebrum

1995 • 72 citations

Topographical and Cytological Evolution of the Glial Phase During Prenatal Development of the Human Brain: Histochemical and Electron Microscopic Study

1988 • 65 citations

Proliferation and differentiation of fetal human oligodendrocytes in culture

1994 • 54 citations

Generation and characterization of brain lipid‐binding protein promoter‐based transgenic mouse models for the study of radial glia

2005 • 48 citations

SONIC HEDGEHOG mutations causing human holoprosencephaly impair neural patterning activity

2003 • 45 citations

Mechanisms of oligodendrocyte commitment in the vertebrate CNS

1999 • 31 citations

Sonic Hedgehog Is a Potent Inducer of Rat Oligodendrocyte Development from Cortical Precursors in Vitro

2002 • 29 citations

Lipopolysaccharide affects Golli expression and promotes proliferation of oligodendrocyte progenitors

2004 • 25 citations

Expression of Oligodendrocyte-Specific Protein/Claudin-11 in the Human Fetal Forebrain

2002 • 17 citations