Nitroglycerin Stimulates Synthesis of Prostacyclin by Cultured Human Endothelial Cells

Culture of Human Endothelial Cells Derived from Umbilical Veins. IDENTIFICATION BY MORPHOLOGIC AND IMMUNOLOGIC CRITERIA

1973 • 6,904 citations

Synthesis of prostaglandin I2 (prostacyclin) by cultured human and bovine endothelial cells.

1977 • 625 citations

Arteriographic evidence of coronary arterial spasm in acute myocardial infarction.

1977 • 533 citations

Synthesis of fibronectin by cultured human endothelial cells.

1978 • 458 citations

UNSTABLE METABOLITES OF ARACHIDONIC ACID AND THEIR ROLE IN HAEMOSTASIS AND THROMBOSIS

1978 • 447 citations

Vascular endothelial and smooth muscle cells in culture selectively release adenine nucleotides

1979 • 402 citations

Synthesis of Prostacyclin from Platelet-derived Endoperoxides by Cultured Human Endothelial Cells

1980 • 385 citations

Recovery of Endothelial Cell Prostacyclin Production after Inhibition by Low Doses of Aspirin

1979 • 310 citations

COMPARISON OF THE VASODEPRESSOR EFFECTS OF PROSTACYCLIN AND 6‐OXO‐PROSTAGLANDIN F_1α WITH THOSE OF PROSTAGLANDIN E₂ IN RATS AND RABBITS

1978 • 277 citations

Effect of propranolol on platelet function

1977 • 233 citations

Effects of sodium nitroprusside, nitroglycerin, and sodium azide on levels of cyclic nucleotides and mechanical activity of various tissues.

1977 • 209 citations

Failure of Intracoronary Nitroglycerin to Alleviate Pacing-Induced Angina

1972 • 202 citations

Enzymatic conversion of prostaglandin endoperoxide H2 and arachidonic acid to prostacyclin by cultured human endothelial cells.

1978 • 196 citations

Inhibition of platelet function by organic nitrate vasodilators

1980 • 187 citations

Prostaglandin endoperoxide and thromboxane generating systems and their selective inhibition

1976 • 176 citations

Pharmacokinetic-hemodynamic studies of intravenous nitroglycerin in congestive cardiac failure.

1980 • 173 citations

Effects of adenosine on levels of adenosine cyclic 3',5'-monophosphate in human blood platelets in relation to adenosine incorporation and platelet aggregation.

1975 • 168 citations

Blood levels after sublingual nitroglycerin.

1979 • 153 citations

Differential effects of adenosine and nitroglycerin on the action potentials of large and small coronary arteries.

1979 • 145 citations

A radioimmunoassay for thromboxane B2

1977 • 134 citations

Relationship between nitroglycerin, cyclic GMP and relaxation of vascular smooth muscle

1979 • 123 citations

Quantitative determination of trinitroglycerin in human plasma.

1979 • 94 citations

Platelet Behaviour and Drugs Used in Cardiovascular Disease

1967 • 90 citations

Effects of aspirin and dipyridamole on the degradation of adenosine diphosphate by cultured cells derived from bovine pulmonary artery.

1980 • 89 citations

Myocardial prostaglandin E release by nitroglycerin and modification by indomethacin

1980 • 88 citations

Metabolism of prostacyclin by 9-hydroxyprostaglandin dehydrogenase in human platelets. Formation of a potent inhibitor of platelet aggregation and enzyme purification.

1980 • 78 citations

SYNTHESIS OF FIBRONECTIN BY CULTURED HUMAN ENDOTHELIAL CELLS

1978 • 77 citations

Effects of stimulant and relaxant drugs on tension and cyclic nucleotide levels in canine femoral artery.

1976 • 76 citations

Plasma nitroglycerin levels after sublingual, oral and topical administration.

1977 • 69 citations

Nitroglycerin compatibility with intravenous fluid filters, containers, and administration sets

1980 • 67 citations

Prostacyclin increases cAMP in coronary arteries.

1979 • 66 citations

Prostaglandins as Inhibitors of Human Platelet Aggregation

1979 • 65 citations

6-keto-prostaglandin E1 inhibits the aggregation of human platelets

1979 • 64 citations

A comparison of imidazole and 9,11-azoprosta-5,13-dienoic acid Two selective thromboxane synthetase inhibitors

1978 • 63 citations

Direct and reflex effects of nitroglycerin on coronary and left ventricular dynamics in conscious dogs

1972 • 58 citations

Prolonged paradoxical effect of aspirin on platelet behaviour and bleeding time in man

1979 • 56 citations

Platelet inhibiton by sodium nitroprusside, a smooth muscle inhibitor

1976 • 55 citations

Enhancement of PGI2 formation by a new vasodilator, 2-nicotinamidoethyl nitrate in the coupled system of platelets and aortic microsomes

1980 • 53 citations

Plasma levels in man of nitroglycerin after buccal administration

1972 • 45 citations

Effects of Nitroglycerin and Propranolol on the Distribution of Transmural Myocardial Blood Flow during Ischemia in the Absence of Hemodynamic Changes in the Unanesthetized Dog

1979 • 38 citations

Stability of nitroglycerin injection determined by gas chromatography

1978 • 35 citations

Radio Immunoassay of Thromboxane B2

1977 • 30 citations

The effects of intracoronary nitroglycerin on left ventricular systolic and diastolic function in man.

1980 • 28 citations

Mechanism of Action of Nitroglycerin: Coronary, Cardiac, and Systemic Effects

1975 • 23 citations

Significance of prostaglandins and thromboxane A2 for the mode of action of cardiovascular drugs.

1980 • 22 citations

Prostaglandins: renal vascular responses to bradykinin, histamine, and nitroglycerine

1978 • 21 citations

The effect of ethanol and nitroglycerin on platelet aggregation.

1970 • 11 citations

Effect of propranolol on platelet function

1977 • 11 citations

Antiplatelet activity of hydralazine

1979 • 11 citations

Inhibition of platelet function by organic nitrate vasodilators

1980 • 9 citations

Quantitative determination of trinitroglycerin in human plasma

1978 • 8 citations

Historical Background

2020 • 1 citations

Chapter II: Statistical Methods

1965 • 1 citations