Characterization of the Reconstructed 1918 Spanish Influenza Pandemic Virus

A simple method of estimating 50 per cent end points

1938 • 8,381 citations

Updating the Accounts: Global Mortality of the 1918-1920 "Spanish" Influenza Pandemic

2002 • 1,760 citations

Molecular Basis for High Virulence of Hong Kong H5N1 Influenza A Viruses

2001 • 1,288 citations

Characterization of the 1918 influenza virus polymerase genes

2005 • 1,063 citations

Rescue of Influenza A Virus from Recombinant DNA

1999 • 780 citations

Initial Genetic Characterization of the 1918 “Spanish” Influenza Virus

1997 • 706 citations

Are We Ready for Pandemic Influenza?

2003 • 662 citations

Origin and evolution of the 1918 “Spanish” influenza virus hemagglutinin gene

1999 • 600 citations

Emerging Infections: Pandemic Influenza

1996 • 474 citations

Enhanced virulence of influenza A viruses with the haemagglutinin of the 1918 pandemic virus

2004 • 457 citations

A Single Amino Acid Substitution in 1918 Influenza Virus Hemagglutinin Changes Receptor Binding Specificity

2005 • 387 citations

Sequence of the 1918 pandemic influenza virus nonstructural gene (NS) segment and characterization of recombinant viruses bearing the 1918 NS genes

2001 • 278 citations

A novel mechanism for the acquisition of virulence by a human influenza A virus

1998 • 235 citations

Characterization of the 1918 “Spanish” influenza virus neuraminidase gene

2000 • 233 citations

The Influenza viruses and influenza

1975 • 230 citations

Pathogenicity and immunogenicity of influenza viruses with genes from the 1918 pandemic virus

2004 • 176 citations

Glycosylation of neuraminidase determines the neurovirulence of influenza A/WSN/33 virus

1993 • 166 citations

Apical Entry and Release of Severe Acute Respiratory Syndrome-Associated Coronavirus in Polarized Calu-3 Lung Epithelial Cells

2005 • 143 citations

Existing antivirals are effective against influenza viruses with genes from the 1918 pandemic virus

2002 • 128 citations

Novel Origin of the 1918 Pandemic Influenza Virus Nucleoprotein Gene

2004 • 121 citations

Characterization of the 1918 “Spanish” Influenza Virus Matrix Gene Segment

2002 • 114 citations

Plasminogen-Binding Activity of Neuraminidase Determines the Pathogenicity of Influenza A Virus

2001 • 103 citations

The pathology of influenza

2010 • 101 citations