Herpes simplex virus type 1 DNA synthesis requires the product of the UL8 gene: isolation and characterization of an ICP6::lacZ insertion mutation

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

A new technique for the assay of infectivity of human adenovirus 5 DNA

1973 • 9,740 citations

The Complete DNA Sequence of the Long Unique Region in the Genome of Herpes Simplex Virus Type 1

1988 • 1,618 citations

Vaccinia virus expression vector: coexpression of beta-galactosidase provides visual screening of recombinant virus plaques.

1985 • 789 citations

The herpes simplex virus amplicon: A new eucaryotic defective-virus cloning-amplifying vector

1982 • 507 citations

Herpes simplex virus type 1-induced ribonucleotide reductase activity is dispensable for virus growth and DNA synthesis: isolation and characterization of an ICP6 lacZ insertion mutant

1988 • 394 citations

Identification of herpes simplex virus type 1 genes required for origin-dependent DNA synthesis

1988 • 328 citations

Molecular genetics of herpes simplex virus. VII. Characterization of a temperature-sensitive mutant produced by in vitro mutagenesis and defective in DNA synthesis and accumulation of gamma polypeptides

1981 • 264 citations

Mutant strains of herpes simplex deficient in thymidine kinase-inducing activity

1964 • 255 citations

A method for identifying the viral genes required for herpesvirus DNA replication.

1986 • 228 citations

Factor(s) present in herpes simplex virus type 1-infected cells can compensate for the loss of the large subunit of the viral ribonucleotide reductase: characterization of an ICP6 deletion mutant

1988 • 226 citations

Cloning, sequencing, and functional analysis of oriL, a herpes simplex virus type 1 origin of DNA synthesis.

1985 • 222 citations

Cloning of herpes simplex virus type 1 sequences representing the whole genome

1981 • 202 citations

Herpes simplex virus DNA replication: the UL9 gene encodes an origin-binding protein.

1988 • 179 citations

Genetic analysis of temperature-sensitive mutants which define the gene for the major herpes simplex virus type 1 DNA-binding protein

1983 • 179 citations

Localization of an origin of DNA replication within the TRS/IRS repeated region of the herpes simplex virus type 1 genome.

1982 • 172 citations

Structures of herpes simplex virus type 1 genes required for replication of virus DNA

1988 • 158 citations

Replication of herpes simplex virus DNA: localization of replication recognition signals within defective virus genomes.

1981 • 155 citations

Identification of the herpes simplex virus DNA polymerase gene

1977 • 149 citations

Ribonucleotide Reductase Activity of Synchronized KB Cells Infected with Herpes Simplex Virus

1972 • 139 citations

A DNA binding protein specific for an origin of replication of herpes simplex virus type 1.

1986 • 136 citations

Collaborative complementation study of temperature-sensitive mutants of herpes simplex virus types 1 and 2

1978 • 132 citations

Ribonucleotide Reductase Induced by Herpes Simplex Virus has a Virus-specified Constituent

1983 • 125 citations

The 65,000-Mr DNA-binding and virion trans-inducing proteins of herpes simplex virus type 1

1987 • 121 citations

An ICP6::lacZ insertional mutagen is used to demonstrate that the UL52 gene of herpes simplex virus type 1 is required for virus growth and DNA synthesis

1988 • 121 citations

DNA synthesis and DNA polymerase activity of herpes simplex virus type 1 temperature-sensitive mutants

1975 • 120 citations

A DNA helicase induced by herpes simplex virus type 1

1988 • 119 citations

Interaction of origin binding protein with an origin of replication of herpes simplex virus 1.

1988 • 118 citations

Cloning, Sequencing, and Functional Analysis of ori_L, a Herpes Simplex Virus Type 1 Origin of DNA Synthesis

1985 • 112 citations

Genetic analysis of temperature-sensitive mutants of HSV-1: The combined use of complementation and physical mapping for cistron assignment

1983 • 100 citations

DNA-binding protein associated with herpes simplex virus DNA polymerase

1985 • 89 citations

Vaccinia virus vectors utilizing the β-galactosidase assay for rapid selection of recombinant viruses and measurement of gene expression

1986 • 84 citations

A New DNA-exonuclease in Cells Infected with Herpes Virus: Partial Purification and Properties of the Enzyme

1968 • 81 citations

Identification of the gene encoding the 65-kilodalton DNA-binding protein of herpes simplex virus type 1

1988 • 78 citations

Induction of uracil-DNA glycosylase and dUTP nucleotidohydrolase activity in herpes simplex virus-infected human cells.

1981 • 76 citations

Identification of the herpes simplex virus type 1 gene encoding the dUTPase

1984 • 75 citations

Genetic and phenotypic characterization of mutants in four essential genes that map to the left half of HSV-1 UL DNA

1987 • 71 citations

Hydroxylamine mutagenesis of HSV DNA and DNA fragments: Introduction of mutations into selected regions of the viral genome

1979 • 70 citations

A temperature-sensitive mutation in a herpes simplex virus type 1 gene required for viral DNA synthesis maps to coordinates 0.609 through 0.614 in UL

1988 • 60 citations

Thermolabile in vivo DNA-binding activity associated with a protein encoded by mutants of herpes simplex virus type 1

1983 • 59 citations

Isolation and characterization of herpes simplex virus type 1 host range mutants defective in viral DNA synthesis

1988 • 54 citations

Isolation of a herpes simplex virus cDNA encoding the DNA repair enzyme uracil-DNA glycosylase

1987 • 50 citations

Physical Mapping of Temperature-sensitive Mutations of Herpes Simplex Virus Type 1 Using Cloned Restriction Endonuclease Fragments

1983 • 47 citations

UL5, A protein required for HSV DNA synthesis: Genetic analysis, overexpression in Escherichia coli, and generation of polyclonal antibodies

1988 • 44 citations

mRNA- and DNA-directed synthesis of herpes simplex virus-coded exonuclease in Xenopus laevis oocytes

1982 • 40 citations

A rapid and simple method for the isolation of high molecular weight cellular and chromosome-specific DNA in solution without the use of organic solvents

1987 • 40 citations

Alkaline DNase activity in cells infected with a temperature-sensitive mutant of herpes simplex virus type 2

1978 • 37 citations

Temperature-sensitive Mutants in Two Distinct Complementation Groups of Herpes Simplex Virus Type 1 Specify Thermolabile DNA Polymerase

1981 • 37 citations

Genome locations of temperature-sensitive mutants in glycoprotein gB of herpes simplex virus type 1

1984 • 17 citations

Identification and characterization of a DNA primase activity present in herpes simplex virus type 1-infected HeLa cells

1988 • 16 citations