Herpes simplex virus type 1-induced ribonucleotide reductase activity is dispensable for virus growth and DNA synthesis: isolation and characterization of an ICP6 lacZ insertion mutant

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

A new technique for the assay of infectivity of human adenovirus 5 DNA

1973 • 9,740 citations

Transformation of mammalian cells to antibiotic resistance with a bacterial gene under control of the SV40 early region promoter.

1982 • 2,753 citations

Regulation of Herpesvirus Macromolecular Synthesis I. Cascade Regulation of the Synthesis of Three Groups of Viral Proteins

1974 • 1,479 citations

Reduction of Ribonucleotides

1979 • 1,170 citations

Vaccinia virus expression vector: coexpression of beta-galactosidase provides visual screening of recombinant virus plaques.

1985 • 789 citations

Isolation and characterization of deletion mutants of herpes simplex virus type 1 in the gene encoding immediate-early regulatory protein ICP4

1985 • 702 citations

Monoclonal antibodies to herpes simplex virus type 1 proteins, including the immediate-early protein ICP 4

1981 • 436 citations

Trans activation of transcription by herpes virus products: requirement for two HSV-1 immediate-early polypeptides for maximum activity.

1984 • 396 citations

Evidence for a direct role for both the 175,000- and 110,000-molecular-weight immediate-early proteins of herpes simplex virus in the transactivation of delayed-early promoters

1985 • 345 citations

The pathogenicity of thymidine kinase-deficient mutants of herpes simplex virus in mice

1978 • 337 citations

Deletion mutants in the gene encoding the herpes simplex virus type 1 immediate-early protein ICP0 exhibit impaired growth in cell culture

1987 • 333 citations

Proteins Specified by Herpes Simplex Virus XI. Identification and Relative Molar Rates of Synthesis of Structural and Nonstructural Herpes Virus Polypeptides in the Infected Cell

1973 • 317 citations

Induction of Both Thymidine and Deoxycytidine Kinase Activity by Herpes Viruses

1974 • 287 citations

Identification of immediate early genes from herpes simplex virus that transactivate the virus thymidine kinase gene.

1985 • 267 citations

Mutant strains of herpes simplex deficient in thymidine kinase-inducing activity

1964 • 255 citations

Herpes simplex virus phosphoproteins. I. Phosphate cycles on and off some viral polypeptides and can alter their affinity for DNA

1980 • 251 citations

Pathogenicity in mice of strains of herpes simplex virus which are resistant to acyclovir in vitro and in vivo

1980 • 245 citations

Cell cycle-dependent regulation of mammalian ribonucleotide reductase. The S phase-correlated increase in subunit M2 is regulated by de novo protein synthesis.

1984 • 244 citations

Stimulation of expression of a herpes simplex virus DNA-binding protein by two viral functions.

1985 • 242 citations

A method for identifying the viral genes required for herpesvirus DNA replication.

1986 • 228 citations

Cloning, sequencing, and functional analysis of oriL, a herpes simplex virus type 1 origin of DNA synthesis.

1985 • 222 citations

Host Range Mutants of Polyoma Virus

1970 • 215 citations

Control of Protein Synthesis in Herpesvirus-infected Cells: Analysis of the Polypeptides Induced by Wild Type and Sixteen Temperature-sensitive Mutants of HSV strain 17

1976 • 211 citations

Cloning of herpes simplex virus type 1 sequences representing the whole genome

1981 • 202 citations

Genetic analysis of temperature-sensitive mutants which define the gene for the major herpes simplex virus type 1 DNA-binding protein

1983 • 179 citations

Trigeminal Ganglion Infection by Thymidine Kinase-Negative Mutants of Herpes Simplex Virus

1979 • 175 citations

Stimulation of Expression of a Herpes Simplex Virus DNA-Binding Protein by Two Viral Functions

1985 • 165 citations

Herpes simplex virus thymidine kinase expression in infection of the trigeminal ganglion

1979 • 159 citations

Separation and characterization of herpes simplex virus type 1 immediate-early mRNA's

1979 • 155 citations

Ribonucleotide Reductase Induced by Herpes Simplex Virus has a Virus-specified Constituent

1983 • 125 citations

DNA synthesis and DNA polymerase activity of herpes simplex virus type 1 temperature-sensitive mutants

1975 • 120 citations

Cloning, Sequencing, and Functional Analysis of ori_L, a Herpes Simplex Virus Type 1 Origin of DNA Synthesis

1985 • 112 citations

Identification of a Herpes Simplex Virus Type 1 Polypeptide Which Is a Component of the Virus-induced Ribonucleotide Reductase

1984 • 111 citations

Localization of ribonucleotide reductase in mammalian cells.

1984 • 106 citations

The Ribonucleotide Reductase Induced by Herpes Simplex Virus Type 1 Involves Minimally a Complex of Two Polypeptides (136K and 38K)

1985 • 95 citations

Partial purification and characterization of the ribonucleotide reductase induced by herpes simplex virus infection of mammalian cells

1981 • 95 citations

Detailed characterization of the mRNA mapping in the HindIII fragment K region of the herpes simplex virus type 1 genome

1981 • 91 citations

Vaccinia virus vectors utilizing the β-galactosidase assay for rapid selection of recombinant viruses and measurement of gene expression

1986 • 84 citations

Mutations in the herpes simplex virus major DNA-binding protein gene leading to altered sensitivity to DNA polymerase inhibitors

1985 • 84 citations

Organization of the Herpes Simplex Virus Type 1 Transcription Unit Encoding Two Early Proteins with Molecular Weights of 140000 and 40000

1983 • 76 citations

Herpes simplex virus specifies two subunits of ribonucleotide reductase encoded by 3'-coterminal transcripts

1986 • 76 citations

Physical mapping of herpes simplex virus type 1 ts mutants by marker rescue: Correlation of the physical and genetic maps

1980 • 75 citations

Ribonucleotide Reductase from Herpes Simplex Virus (Types 1 and 2) Infected and Uninfected KB Cells: Properties of the Partially Purified Enzymes

1977 • 74 citations

Characterization of Ribonucleotide Reductase Induction in BHK-21/C13 Syrian Hamster Cell Line Upon Infection by Herpes Simplex Virus (HSV)

1981 • 73 citations

Immunological characterization of herpes simplex virus type 1 and 2 polypeptide(s) involved in viral ribonucleotide reductase activity

1984 • 68 citations

Vaccinia virus induces ribonucleotide reductase in primate cells

1984 • 52 citations

Aanlysis of dCMP deaminase and CDP reductase levels in hamster cells infected by herpes simplex virus

1978 • 51 citations

Selective inhibition of herpes simplex virus ribonucleoside diphosphate reductase by derivatives of 2-acetylpyridine thiosemicarbazone

1986 • 47 citations

Isolation and localization of herpes simplex virus type 1 mRNA abundant before viral DNA synthesis

1979 • 46 citations

Herpes Simplex Virus-induced Ribonucleotide Reductase: Development of Antibodies Specific for the Enzyme

1983 • 33 citations

trans-dominant defective mutants of simian virus 40 T antigen

1987 • 28 citations

Can ribonucleotide reductase be considered as an effective target for developing antiherpes simplex virus type II (HSV-2) compounds?

1985 • 23 citations

Replication of herpes simplex virus type 1 on hydroxyurea-resistant baby hamster kidney cells

1983 • 15 citations

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