Acute oxygen supplementation restores markers of hepatocyte energy status and hypoxia in cirrhotic rats.

High Yield Micronodular Cirrhosis in the Rat

1982 • 289 citations

Clinical Pharmacokinetic and Pharmacodynamic Considerations in Patients with Liver Disease

1995 • 200 citations

Phosphorylation status of liver by 31P-n.m.r. spectroscopy, and its implications for metabolic control. A comparison of 31P-n.m.r. spectroscopy (in vivo and in vitro) with chemical and enzymic determinations of ATP, ADP and Pi

1985 • 174 citations

Clinical Pharmacokinetics in Patients with Liver Disease

1991 • 147 citations

Hypoxia and drug metabolism

1981 • 122 citations

Propranolol Disposition in Chronic Liver Disease

1976 • 102 citations

Effect of functional grade and etiology onin vivo hepatic phosphorus-31 magnetic resonance spectroscopy in cirrhosis: Biochemical basis of spectral appearances

1995 • 101 citations

Alcoholic liver disease: quantitative image-guided P-31 MR spectroscopy.

1989 • 93 citations

Mechanisms of hypoxic cell injury

1990 • 91 citations

Aminopyrine N-demethylation by rats with liver cirrhosis

1987 • 83 citations

Adenosine Partially Prevents Cirrhosis Induced by Carbon Tetrachloride in Rats

1990 • 76 citations

Interaction between oral propranolol and hydralazine

1980 • 66 citations

Hepatic metabolism during acute ethanol administration: A phosphorus-31 nuclear magnetic resonance study on the perfused rat liver under normoxic or hypoxic conditions

1987 • 52 citations

Low oral bioavailability of dihydroergotamine and first-pass extraction in patients with Orthostatic hypotension

1981 • 50 citations

Drug Metabolism and Toxicity During Hypoxia

1989 • 50 citations

Hepatic phosphorus-31 magnetic resonance spectroscopy in primary biliary cirrhosis and its relation to prognostic models.

1996 • 48 citations

Effect of functional grade and etiology on in vivo hepatic phosphorus-31 magnetic resonance spectroscopy in cirrhosis: Biochemical basis of spectral appearances*1

1995 • 46 citations

Possible role of cell redox state on collagen metabolism in carbon tetrachloride-induced cirrhosis as evidenced by adenosine administration to rats

1994 • 44 citations

Comparative effects of oxygen supplementation on theophylline and acetaminophen clearance in human cirrhosis

1999 • 41 citations

A ³¹p nuclear magnetic resonance study in vivo of metabolic abnormalities in rats with acute liver failure

1988 • 38 citations

Hepatic artery flow and propranolol metabolism in perfused cirrhotic rat liver.

1999 • 36 citations

Oxygen supplementation restores theophylline clearance to normal in cirrhotic rats

1995 • 35 citations

Cirrhosis of the human liver: an in vitro 31P nuclear magnetic resonance study

1995 • 34 citations

Nicotinamide methylation in patients with cirrhosis

1994 • 33 citations

Clinical magnetic resonance spectroscopy of brain, heart, liver, kidney, and cancer. A quantitative approach

1989 • 33 citations

31P and1H NMR spectroscopic studies of liver extracts of carbon tetrachloride-treated rats

1999 • 33 citations

Increased sensitivity of propranolol clearance to reduced oxygen delivery in the isolated perfused cirrhotic rat liver

1996 • 26 citations

The effects of chronic ethanol consumption on the intact rat liver studied by in vivo³¹P NMR spectroscopy

1991 • 20 citations

Effect of hepatocyte volume on energy status in the cirrhotic rat liver

1994 • 15 citations

Nicotinamide methylation and hepatic energy reserve: a study by liver perfusion in vitro

1995 • 12 citations

Interaction between oral hydralazine and propranolol. I. Changes in absorption, presystemic clearance and splanchnic blood flow.

1984 • 11 citations

Influence of hypoxia on mitochondrial function and energy status in CCl4-induced cirrhotic rat liver

1989 • 11 citations

The effects of hypoxia on the bioenergetics of liver in situ in chronic ethanol-treated rats: a noninvasive in vivo 31P magnetic resonance spectroscopy study.

1997 • 7 citations

Influence of hydralazine on the pharmacokinetics of orally administered d-propranolol and lidocaine in conscious dogs.

1987 • 4 citations