Mechanisms of B cell tolerance

The carrier effect in the secondary response to hapten‐protein conjugates. I. Measurement of the effect with transferred cells and objections to the local environment hypothesis

1971 • 319 citations

THE RELATIONSHIP BETWEEN ANTIGENIC STRUCTURE AND THE REQUIREMENT FOR THYMUS-DERIVED CELLS IN THE IMMUNE RESPONSE

1971 • 282 citations

Immunological Unresponsiveness

1973 • 278 citations

Differences in susceptibility of mature and immature mouse B lymphocytes to anti-immunoglobulin-induced immunoglobulin suppression in vitro. Possible implications for B-cell tolerance to self.

1975 • 228 citations

A one‐step procedure for separating mouse T and B lymphocytes

1974 • 208 citations

Cell surface immunoglobulin. XI. The appearance of an IgD-like molecule on murine lymphoid cells during ontogeny.

1975 • 200 citations

CARRIER FUNCTION IN ANTI-HAPTEN ANTIBODY RESPONSES

1971 • 190 citations

Receptor-mediated inactivation of early B lymphocytes

1975 • 187 citations

Candidate for immunoglobulin D present on murine B lymphocytes

1974 • 170 citations

General Method for the Detection of Cells producing Antibodies against Haptens and Proteins

1970 • 155 citations

IMMUNOLOGICAL TOLERANCE IN BONE MARROW-DERIVED LYMPHOCYTES

1972 • 134 citations

Inhibition of secondary anti‐hapten responses with the hapten conjugated to type 3 pneumococcal polysaccharide

1972 • 128 citations

Neonatal Tolerance Induced by Antibody against Antigen-Specific Receptor

1974 • 97 citations

The Tolerant Cell: Direct Evidence for Receptor Blockade by Tolerogen

1974 • 93 citations

The immunological properties of haptens coupled to thymus-independent carrier molecules. I. The characteristics of the immune response to dinitrophenyllysinesubstituted pneumococcal polysaccharide (SIII) and levan

1974 • 72 citations

Antigen Recognition: Early Surface-Receptor Phenomena Induced by Binding of a Tritium-Labeled Antigen

1972 • 68 citations

The influence of epitope density on the immunological properties of hapten-protein conjugates

1974 • 67 citations

Model for the binding of multivalent antigen to cells

1974 • 66 citations

Antigen-induced aggregation and modulation of receptors on hapten-specific B lymphocytes.

1976 • 63 citations

Studies on immunological paralysis. II. The detection and significance of antibod-forming cells in the spleen during immunological paralysis with type 3 pneumococcal polysaccharide.

1969 • 61 citations

INDUCTION OF B CELL TOLERANCE IN VITRO TO 2,4-DINITROPHENYL COUPLED TO A COPOLYMER OF <scp>D</scp>-GLUTAMIC ACID AND <scp>D</scp>-LYSINE (DNP-<scp>D</scp>-GL)

1973 • 59 citations

ANTIGEN-BINDING CELLS IN MICE IMMUNE OR TOLERANT TO ESCHERICHIA COLI POLYSACCHARIDE

1971 • 57 citations

Loss of Carrier-Determined Tolerance in Vitro with Loss of Receptor Blockade

1976 • 46 citations

Failure of Lymphocytes to Reexpress Antigen Receptors after Brief Interaction with a Tolerogenic D-Amino Acid Copolymer

1974 • 43 citations

FATE OF ANTIGEN-BINDING CELLS IN UNRESPONSIVE AND IMMUNE MICE

1973 • 43 citations

B cell tolerance induced by polymeric antigens. I. Comparison of thedose and epitope density requirement for inactivation of primed and unprimed B cells in vivo

1975 • 42 citations

Binding of <sup>125</sup>I-BSA to Lymphoid Cells of Tolerant Mice

1969 • 39 citations

Induction of primary and inhibition of secondary antibody response to hapten by hapten conjugates of type III pneumococcal polysaccharide

1975 • 37 citations

Antigen recognition. IV. Discrimination by antigen-binding immunocompetent B cells between immunity and tolerance is determined by adherent cells.

1976 • 36 citations

Mechanisms of B cell tolerance

1977 • 26 citations

B cell tolerance induced by polymeric antigens. II. Effects of tolerance on hapten‐binding lymphocyte levels in primary and secondaryantibody responses

1975 • 26 citations

Studies on immunological paralysis. XI. A comparison of the tolerogenicity in vitro of levan and type 3 pneumococcal polysaccharide

1973 • 23 citations

B cell tolerance induced by polymeric antigens. VI. Kinetics and reversibility of the inhibition of antibody‐forming cells by antigen

1976 • 23 citations

Requirement for persistent extracellular antigen in cultures of antigen-binding B lymphocytes.

1976 • 17 citations

Mechanisms by which hapten conjugates of pneumococcal polysaccharide interfere with the challenge of anti‐hapten memory cells

1976 • 11 citations

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