Genetic signatures of differentiation induced by 1alpha,25-dihydroxyvitamin D3 in human colon cancer cells.

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

CONFIDENCE LIMITS ON PHYLOGENIES: AN APPROACH USING THE BOOTSTRAP

1985 • 39,646 citations

Cluster analysis and display of genome-wide expression patterns

1998 • 16,410 citations

Genomic sequencing.

1984 • 8,343 citations

Cancer statistics, 1997

1997 • 2,045 citations

Vitamin D3 promotes the differentiation of colon carcinoma cells by the induction of E-cadherin and the inhibition of β-catenin signaling

2001 • 783 citations

SERUM 25-HYDROXYVITAMIN D AND COLON CANCER: EIGHT-YEAR PROSPECTIVE STUDY

1989 • 665 citations

Convergence of Transforming Growth Factor-β and Vitamin D Signaling Pathways on SMAD Transcriptional Coactivators

1999 • 442 citations

Isolation and characterization of chicken DNA homologous to the two putative oncogenes of avian erythroblastosis virus

1982 • 318 citations

Apoptosis is induced by the active metabolite of vitamin D3 and its analogue EB1089 in colorectal adenoma and carcinoma cells: possible implications for prevention and therapy.

2000 • 308 citations

Molecular nature of the vitamin D receptor and its role in regulation of gene expression.

2001 • 279 citations

Mechanisms implicated in the growth regulatory effects of vitamin D in breast cancer.

2002 • 247 citations

Validation of a model of colon cancer progression

2000 • 212 citations

A Phase I trial of calcitriol (1,25-dihydroxycholecalciferol) in patients with advanced malignancy.

1999 • 181 citations

Expression Profiling in Squamous Carcinoma Cells Reveals Pleiotropic Effects of Vitamin D3 Analog EB1089 Signaling on Cell Proliferation, Differentiation, and Immune System Regulation

2002 • 177 citations

The role for NES1 serine protease as a novel tumor suppressor.

1998 • 173 citations

Vitamin D and cancer: effects of 1,25(OH)2D3 and its analogs on growth control and tumorigenesis

2001 • 169 citations

A phase I study of the vitamin D analogue EB 1089 in patients with advanced breast and colorectal cancer

1998 • 163 citations

Cbl-directed monoubiquitination of CIN85 is involved in regulation of ligand-induced degradation of EGF receptors

2002 • 155 citations

Apoptotic Regression of MCF-7 Xenografts in Nude Mice Treated with the Vitamin D₃Analog, EB1089¹

1998 • 151 citations

Regulation of Gene Expression by 1α,25-Dihydroxyvitamin D₃and Its Analog EB1089 under Growth-Inhibitory Conditions in Squamous Carcinoma Cells

2001 • 149 citations

1alpha,25-dihydroxyvitamin D3 and its analogues down-regulate cell invasion-associated proteases in cultured malignant cells.

2000 • 142 citations

Hypermethylation leads to silencing of the SYK gene in human breast cancer.

2001 • 122 citations

Nuclear receptors and genetic disease

2001 • 114 citations

Vitamin D and cancer

2002 • 106 citations

Core Histones and HIRIP3, a Novel Histone-Binding Protein, Directly Interact with WD Repeat Protein HIRA

1998 • 105 citations

Metastasis-associated protein (MTA)1 enhances migration, invasion, and anchorage-independent survival of immortalized human keratinocytes

2002 • 102 citations

Vitamin D receptor polymorphisms and risk of colorectal adenomas (United States).

2001 • 96 citations

Transcriptional Targets of the Vitamin D3 Receptor–Mediating Cell Cycle Arrest and Differentiation

1999 • 90 citations

Inhibition of tumor cell-induced angiogenesis by retinoids, 1,25-dihydroxyvitamin D3 and their combination

1993 • 87 citations

1,25-Dihydroxyvitamin D3 receptors in normal and malignant human colorectal tissues

1994 • 77 citations

Vitamin D3 analog, EB1089, inhibits growth of subcutaneous xenografts of the human colon cancer cell line, LoVo, in a nude mouse model

1997 • 71 citations

Cell Cycle Arrest Induced by the Vitamin D3 Analog EB1089 in NCI-H929 Myeloma Cells Is Associated with Induction of the Cyclin-Dependent Kinase Inhibitor p27

2000 • 68 citations

Analysis of normal epithelial cell specific-1 (NES1)/kallikrein 10 mRNA expression by in situ hybridization, a novel marker for breast cancer.

2001 • 64 citations

1,25-dihydroxyvitamin D3 synthetic analogs inhibit spontaneous metastases in a 1,2-dimethylhydrazine-induced colon carcinogenesis model.

2000 • 50 citations

Isolation and characterization of a highly malignant variant of the SW480 human colon cancer cell line.

1992 • 47 citations

Association of Vitamin D Receptor Gene Polymorphism with Renal Cell Carcinoma in Japanese.

2002 • 44 citations

MdmX inhibits Smad transactivation

2002 • 41 citations

Identification of single nucleotide polymorphisms in the human kallikrein 10 (KLK10) gene and their association with prostate, breast, testicular, and ovarian cancers

2002 • 40 citations

Sunlight and Vitamin D: The Bone and Cancer Connections

2000 • 16 citations

The Vitamin D Receptor

2001 • 6 citations

Deleted Work

1955 • 0 citations