Natural selection at linked sites in humans
Data up to Jan 2025
Total Citations Per Year
Abstract
References (91)
Initial sequencing and analysis of the human genome
2001 • 23,520 citations
Statistical method for testing the neutral mutation hypothesis by DNA polymorphism.
1989 • 13,216 citations
Mathematical model for studying genetic variation in terms of restriction endonucleases.
1979 • 10,442 citations
The Neutral Theory of Molecular Evolution
1979 • 7,965 citations
The Neutral Theory of Molecular Evolution
1983 • 6,141 citations
An introduction to population genetics theory
1970 • 4,120 citations
On the number of segregating sites in genetical models without recombination
1975 • 3,989 citations
The Genetics and Biology of Drosophila
1978 • 3,910 citations
An Introduction to Population Genetics Theory
1971 • 3,490 citations
The hitch-hiking effect of a favourable gene
1974 • 3,276 citations
A comprehensive genetic map of the human genome based on 5,264 microsatellites
1996 • 2,983 citations
A map of human genome sequence variation containing 1.42 million single nucleotide polymorphisms
2001 • 2,948 citations
The hitch-hiking effect of a favourable gene
2007 • 2,840 citations
Hitchhiking Under Positive Darwinian Selection
2000 • 1,854 citations
The effect of deleterious mutations on neutral molecular variation.
1993 • 1,838 citations
The effect of change in population size on DNA polymorphism.
1989 • 1,373 citations
Estimate of the Mutation Rate per Nucleotide in Humans
2000 • 1,227 citations
Slightly Deleterious Mutant Substitutions in Evolution
1973 • 1,108 citations
The Relative Rates of Evolution of Sex Chromosomes and Autosomes
1987 • 1,072 citations
Microsatellites: Evolution and Applications
1999 • 1,000 citations
Levels of naturally occurring DNA polymorphism correlate with recombination rates in D. melanogaster
1992 • 987 citations
Nucleotide polymorphism at the alcohol dehydrogenase locus of Drosophila melanogaster
1983 • 707 citations
Patterns of DNA sequence polymorphism along chromosome 1 of maize ( Zea mays ssp. mays L.)
2001 • 695 citations
Properties of statistical tests of neutrality for DNA polymorphism data.
1995 • 683 citations
Positive and Negative Selection on the Human Genome
2001 • 669 citations
Detecting Population Expansion and Decline Using Microsatellites
1999 • 629 citations
The hitchhiking effect on the site frequency spectrum of DNA polymorphisms.
1995 • 620 citations
The Signature of Positive Selection at Randomly Chosen Loci
2002 • 518 citations
Sequence variation in the human angiotensin converting enzyme
1999 • 490 citations
Deleterious background selection with recombination.
1995 • 467 citations
Haplotype Structure and Population Genetic Inferences from Nucleotide-Sequence Variation in Human Lipoprotein Lipase
1998 • 439 citations
The pattern of neutral molecular variation under the background selection model.
1995 • 431 citations
Intraspecific nuclear DNA variation in Drosophila
1996 • 425 citations
Archaic African and Asian lineages in the genetic ancestry of modern humans.
1997 • 415 citations
Apolipoprotein E Variation at the Sequence Haplotype Level: Implications for the Origin and Maintenance of a Major Human Polymorphism
2000 • 413 citations
High genomic deleterious mutation rates in hominids
1999 • 405 citations
Microsatellites — Evolution and Applications
1999 • 395 citations
Detection of the Signature of Natural Selection in Humans: Evidence from the Duffy Blood Group Locus
2000 • 352 citations
The effect of recombination on background selection
1996 • 331 citations
Single nucleotide polymorphisms and recombination rate in humans
2001 • 314 citations
Synonymous and nonsynonymous substitutions in mammalian genes and the nearly neutral theory
1995 • 303 citations
Male-driven Molecular Evolution: A Model and Nucleotide Sequence Analysis
1987 • 293 citations
Comparison of human genetic and sequence-based physical maps
2001 • 281 citations
Adjusting the focus on human variation
2000 • 278 citations
Gene Conversion and Different Population Histories May Explain the Contrast between Polymorphism and Linkage Disequilibrium Levels
2001 • 277 citations
Background selection and patterns of genetic diversity inDrosophila melanogaster
1996 • 265 citations
Strong male-driven evolution of DNA sequences in humans and apes
2002 • 260 citations
Lack of polymorphism on the Drosophila fourth chromosome resulting from selection.
1991 • 257 citations
Contrasting Patterns of X-Linked and Autosomal Nucleotide Variation in Drosophila melanogaster and Drosophila simulans
2001 • 245 citations
DNA sequence variation in a non-coding region of low recombination on the human X chromosome
1999 • 242 citations
Low mutation rates of microsatellite loci in Drosophila melanogaster
1997 • 242 citations
X chromosome evidence for ancient human histories
1999 • 229 citations
Reduced variation in the yellow-achaete-scute region in natural populations of Drosophila melanogaster.
1989 • 214 citations
Analysis of a genetic hitchhiking model, and its application to DNA polymorphism data from Drosophila melanogaster.
1993 • 212 citations
Larger Genetic Differences Within Africans Than Between Africans and Eurasians
2002 • 210 citations
DNA Variability and Recombination Rates at X-Linked Loci in Humans
1998 • 204 citations
Joint Effects of Genetic Hitchhiking and Background Selection on Neutral Variation
2000 • 193 citations
Worldwide DNA sequence variation in a 10-kilobase noncoding region on human chromosome 22
2000 • 182 citations
An introduction to population genetics.
1950 • 180 citations
Adaptive hitchhiking effects on genome variability
2001 • 176 citations
Reduced X-linked nucleotide polymorphism inDrosophila simulans
2000 • 173 citations
Restriction Fragment Length Polymorphism and Divergence in the Genomic Regions of High and Low Recombination in Self-Fertilizing and Cross-Fertilizing Aegilops Species
1998 • 169 citations
The effect of life-history and mode of inheritance on neutral genetic variability
2001 • 154 citations
Global Patterns of Human DNA Sequence Variation in a 10-kb Region on Chromosome 1
2001 • 152 citations
DNA Polymorphism in Lycopersicon and Crossing-Over per Physical Length
1998 • 148 citations
Evidence for a selectively favourable reduction in the mutation rate of the X chromosome
1997 • 145 citations
Molecular population genetics of the distal portion of the X chromosome in Drosophila: evidence for genetic hitchhiking of the yellow-achaete region.
1991 • 139 citations
Selection, Recombination, and DNA Polymorphism in Drosophila
1994 • 138 citations
Hitchhiking and associative overdominance at a microsatellite locus.
1995 • 136 citations
Molecular genetic variation in the centromeric region of the X chromosome in three Drosophila ananassae populations. I. Contrasts between the vermilion and forked loci.
1989 • 132 citations
Microsatellite Variation and Recombination Rate in the Human Genome
2000 • 131 citations
Non-neutral Evolution: Theories and Molecular Data
1995 • 124 citations
Patterns of DNA Variability at X-Linked Loci in Mus domesticus
1997 • 117 citations
Regions of Lower Crossing Over Harbor More Rare Variants in African Populations of Drosophila melanogaster
2001 • 111 citations
Chromosomal Patterns of Microsatellite Variability Contrast Sharply in African and Non-African Populations of Drosophila melanogaster
2002 • 104 citations
USING HITCHHIKING GENES TO STUDY ADAPTATION AND DIVERGENCE DURING SPECIATION WITHIN THE DROSOPHILA MELANOGASTER SPECIES COMPLEX
1994 • 93 citations
The population genetics of haplo-diploids and X-linked genes
1984 • 93 citations
Nucleotide Variation Along the Drosophila melanogaster Fourth Chromosome
2002 • 89 citations
Microsatellites, a neutral marker to infer selective sweeps
1999 • 88 citations
Length Variation of CAG/CAA Trinucleotide Repeats in Natural Populations of Drosophila melanogaster and Its Relation to the Recombination Rate
1996 • 81 citations
The Effect of Selective Sweeps on the Variance of the Allele Distribution of a Linked Multiallele Locus: Hitchhiking of Microsatellites
1998 • 78 citations
Patterns of Genetic Variation at a Chromosome 4 Locus of Drosophila melanogaster and D. simulans
2002 • 78 citations
Contrasting Evolutionary Histories of Two Introns of the Duchenne Muscular Dystrophy Gene, Dmd, in Humans
2000 • 72 citations
A highly variable segment of human subterminal 16p reveals a history of population growth for modern humans outside Africa
2000 • 72 citations
Spatial and Temporal Distribution of the Neutral Polymorphisms in the Last ZFX Intron: Analysis of the Haplotype Structure and Genealogy
1999 • 65 citations
Positive Correlation Between Recombination Rates and Levels of Genetic Variation in Natural Populations of Sea Beet (Beta vulgaris subsp. maritima)
1998 • 64 citations
Alternatives to the Neutral Theory
1994 • 49 citations
New alleles at microsatellite loci in CEPH families mainly arise from somatic mutations in the lymphoblastoid cell lines
1994 • 48 citations
Mutation and evolution of microsatellites in Drosophila melanogaster
1998 • 46 citations
Human populations show reduced DNA sequence variation at the Factor IX locus
2001 • 34 citations
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1998 • 32 citations