Treatment of atypical endometrial hyperplasia with an insulin-sensitizing agent

The behavior of endometrial hyperplasia. A long-term study of “untreated” hyperplasia in 170 patients

1985 • 1,243 citations

Metabolic Effects of Metformin in Non-Insulin-Dependent Diabetes Mellitus

1995 • 1,135 citations

Mechanism by which metformin reduces glucose production in type 2 diabetes.

2000 • 1,017 citations

Association of Exogenous Estrogen and Endometrial Carcinoma

1975 • 950 citations

Insulin Receptor Isoform A, a Newly Recognized, High-Affinity Insulin-Like Growth Factor II Receptor in Fetal and Cancer Cells

1999 • 865 citations

The accuracy of endometrial sampling in the diagnosis of patients with endometrial carcinoma and hyperplasia

2000 • 431 citations

Reproductive, menstrual, and medical risk factors for endometrial cancer: Results from a case-control study

1992 • 379 citations

A case-control study of diabetes mellitus and cancer risk

1994 • 329 citations

Tissue-Specific Expression of Two Alternatively Spliced Insulin Receptor mRNAs in Man

1989 • 308 citations

Pituitary-ovarian relationships preceding the menopause

1977 • 241 citations

Reproductive Factors and Risk of Endometrial Cancer The Iowa Women's Health Study

1996 • 214 citations

Steroid and peptide regulation of insulin-like growth factor-binding proteins secreted by human endometrial stromal cells is dependent on stromal differentiation.

1992 • 112 citations

Upper-body fat distribution and endometrial cancer risk.

1991 • 104 citations

Upper-Body Fat Distribution and Endometrial Cancer Risk

1991 • 86 citations

Insulin-like growth factor I receptors in normal and neoplastic human endometrium.

1990 • 77 citations

Suppressed expression of insulin‐like growth factor binding protein‐1 mRNA in the endometrium: A molecular mechanism associating endometrial cancer with its risk factors

1994 • 70 citations

Body fat patterning in women with endometrial cancer

1990 • 62 citations

Relationship between carbohydrate metabolism and serum insulin-like growth factor system in postmenopausal women: comparison of endometrial cancer patients with healthy controls.

1993 • 52 citations

Regulation of endometrial cancer cell growth by insulin-like growth factors and the luteinizing hormone-releasing hormone antagonist SB-75

1993 • 49 citations

Androstenedione metabolism in patients with endometrial cancer

1977 • 49 citations

Insulin and glucose status, tissue and plasma lipids in patients with tumours of the ovary or endometrium: possible dietary implications

1994 • 20 citations

CARBOHYDRATE METABOLISM IN PATIENTS WITH ENDOMETRIAL CARCINOMA

1974 • 13 citations

Hyperinsulinemia as a factor modifying sensitivity of endometrial carcinoma to hormonal influences.

1993 • 7 citations