Correlates of Protective Immunity to Mycobacterium tuberculosis in Humans

An essential role for interferon gamma in resistance to Mycobacterium tuberculosis infection.

1993 • 2,410 citations

Disseminated tuberculosis in interferon gamma gene-disrupted mice.

1993 • 1,982 citations

An Antimicrobial Activity of Cytolytic T Cells Mediated by Granulysin

1998 • 1,019 citations

Interferon-γ –Receptor Deficiency in an Infant with Fatal Bacille Calmette–Guérin Infection

1996 • 869 citations

Partial interferon-gamma receptor 1 deficiency in a child with tuberculoid bacillus Calmette-Guérin infection and a sibling with clinical tuberculosis.

1997 • 383 citations

Cytokine production at the site of disease in human tuberculosis

1993 • 379 citations

Treatment of multidrug-resistant pulmonary tuberculosis with interferon-γ via aerosol

1997 • 309 citations

Familial disseminated atypical mycobacterial infection in childhood: a human mycobacterial susceptibility gene?

1995 • 217 citations

Cross-modulation by transforming growth factor beta in human tuberculosis: suppression of antigen-driven blastogenesis and interferon gamma production.

1996 • 212 citations

CD4+ alpha beta T cell and gamma delta T cell responses to Mycobacterium tuberculosis. Similarities and differences in Ag recognition, cytotoxic effector function, and cytokine production.

1995 • 184 citations

In vitrorestoration of T cell responses in tuberculosis and augmentation of monocyte effector function againstMycobacterium tuberculosisby natural inhibitors of transforming growth factor β

1997 • 148 citations

Human alveolar T lymphocyte responses to Mycobacterium tuberculosis antigens: role for CD4+ and CD8+ cytotoxic T cells and relative resistance of alveolar macrophages to lysis.

1997 • 133 citations

Lymphocyte-Dependent Inhibition of Growth of VirulentMycobacterium tuberculosisH37Rv Within Human Monocytes: Requirement for CD4+ T Cells in Purified Protein Derivative-Positive, But Not in Purified Protein Derivative-Negative Subjects

1998 • 121 citations

Human Purified Protein Derivative-Specific CD4+ T Cells Use Both CD95-Dependent and CD95-Independent Cytolytic Mechanisms

1998 • 81 citations

Development of a whole blood assay to measure T cell responses to leprosy: a new tool for immuno-epidemiological field studies of leprosy immunity

1994 • 77 citations

Characterization of a 10- to 14-kilodalton protease-sensitive Mycobacterium tuberculosis H37Ra antigen that stimulates human gamma delta T cells

1994 • 54 citations

Simultaneous quantitation of multiple cytokine mRNAs by RT-PCR utilizing plate based EIA methodology

1995 • 39 citations