CD8 T-cell recognition of macrophages and hepatocytes results in immunity to Listeria monocytogenes

Mice lacking the tumour necrosis factor receptor 1 are resistant to IMF-mediated toxicity but highly susceptible to infection by Listeria monocytogenes

1993 • 1,267 citations

Intracellular Inactivation of the Hepatitis B Virus by Cytotoxic T Lymphocytes

1996 • 1,085 citations

Immunity to Intracellular Bacteria

1993 • 1,085 citations

β2-Microglobulin deficient mice lack CD4−8+ cytolytic T cells

1990 • 997 citations

Normal Development of Mice Deficient in β ₂ M, MCClass I Proteins, and CD8 ⁺ T Cells

1990 • 885 citations

Interleukin 12 and tumor necrosis factor alpha are costimulators of interferon gamma production by natural killer cells in severe combined immunodeficiency mice with listeriosis, and interleukin 10 is a physiologic antagonist.

1993 • 792 citations

L. monocytogenes-induced actin assembly requires the actA gene product, a surface protein

1992 • 790 citations

Molecular determinants of Listeria monocytogenes pathogenesis

1992 • 571 citations

Requirement of endogenous interferon-gamma production for resolution of Listeria monocytogenes infection.

1985 • 555 citations

Specific immunity to listeria monocytogenes in the absence of IFNγ

1995 • 432 citations

Precise prediction of a dominant class I MHC-restricted epitope of Listeria monocytogenes

1991 • 425 citations

Adoptive transfer of immunity to Listeria monocytogenes. The influence of in vitro stimulation on lymphocyte subset requirements.

1987 • 387 citations

Neutrophils are essential for early anti-Listeria defense in the liver, but not in the spleen or peritoneal cavity, as revealed by a granulocyte-depleting monoclonal antibody.

1994 • 352 citations

Natural Immunity: A T‐Cell‐Independent Pathway of Macrophage Activation, Defined in the scid Mouse

1991 • 321 citations

Neutralization of IL-12 decreases resistance to Listeria in SCID and C.B-17 mice. Reversal by IFN-gamma.

1994 • 305 citations

Identity of cells that imprint H–2-restricted T-cell specificity in the thymus

1986 • 267 citations

CD8+ T cells specific for a single nonamer epitope of Listeria monocytogenes are protective in vivo.

1992 • 260 citations

Administration of anti-granulocyte mAb RB6-8C5 impairs the resistance of mice to Listeria monocytogenes infection.

1994 • 242 citations

CD8+ T cell-mediated protection against an intracellular bacterium by perforin-dependent cytotoxicity

1994 • 229 citations

Gamma interferon limits access of Listeria monocytogenes to the macrophage cytoplasm.

1989 • 215 citations

Listeria monocytogenes induces apoptosis of infected hepatocytes.

1996 • 213 citations

Presentation of Listeria monocytogenes to CD8+ T cells requires secretion of hemolysin and intracellular bacterial growth.

1990 • 208 citations

H-2M3 presents a listeria monocytogenes peptide to cytotoxic T lymphocytes

1992 • 203 citations

Fate of Listeria monocytogenes in murine macrophages: evidence for simultaneous killing and survival of intracellular bacteria

1994 • 180 citations

Monoclonal antibodies specific for murine p55 and p75 tumor necrosis factor receptors: identification of a novel in vivo role for p75.

1995 • 163 citations

Direct sequence identification and kinetic analysis of an MHC class I-restricted Listeria monocytogenes CTL epitope.

1994 • 161 citations

Specialized Role for a Murine Class I-b MHC Molecule in Prokaryotic Host Defenses

1992 • 135 citations

Dissection of major histocompatibility complex (MHC) and T cell receptor contact residues in a K^b‐restricted ovalbumin peptide and an assessment of the predictive power of MHC‐binding motifs

1992 • 134 citations

Listeria monocytogenes-reactive T lymphocyte clones with cytolytic activity against infected target cells.

1986 • 134 citations

Specific Lyt 123 cells are involved in protection against Listeria monocytogenes and in delayed-type hypersensitivity to listerial antigens.

1979 • 132 citations

Distinct mechanisms of extrathymic T cell tolerance due to differential expression of self antigen

1992 • 128 citations

Effects of cytotoxic monoclonal antibody specific for T200 glycoprotein on functional lymphoid cell populations

1980 • 125 citations

CD8 T cells can protect against an intracellular bacterium in an interferon gamma-independent fashion.

1992 • 122 citations

Listeria monocytogenes. A model system for the molecular study of intracellular parasitism.

1989 • 121 citations

Cloned Listeria monocytogenes specific non-MHC-restricted Lyt-2+ T cells with cytolytic and protective activity.

1988 • 107 citations

Non‐Deletional Mechanisms of Peripheral and Central Tolerance: Studies with Transgenic Mice with Tissue‐Specific Expression of a Foreign MHC Class I Antigen

1991 • 107 citations

CD8 T lymphocytes specific for the secreted p60 antigen protect against Listeria monocytogenes infection.

1995 • 105 citations

Effector function of hepatocytes and Kupffer cells in the resolution of systemic bacterial infections

1992 • 97 citations

Endogenous IL-1 is required for neutrophil recruitment and macrophage activation during murine listeriosis.

1994 • 95 citations

Acquired resistance to Listeria monocytogenes is mediated by Lyt-2+ T cells independently of the influx of monocytes into granulomatous lesions.

1989 • 86 citations

Multiplication of Listeria monocytogenes in a murine hepatocyte cell line

1993 • 65 citations

Effects of purified anti-Lyt-2 mAb treatment on murine listeriosis: comparative roles of Lyt-2+ and L3T4+ cells in resistance to primary and secondary infection, delayed-type hypersensitivity and adoptive transfer of resistance.

1990 • 63 citations

Neutrophils as effector cells of T-cell-mediated, acquired immunity in murine listeriosis.

1994 • 51 citations

Lyt-2+ T cell-mediated protection against listeriosis. Protection correlates with phagocyte depletion but not with IFN-gamma production.

1989 • 47 citations

IFN-gamma inhibits the replication of Listeria monocytogenes in hepatocytes.

1993 • 43 citations

An H2-T MHC class Ib molecule presents Listeria monocytogenes-derived antigen to immune CD8+ cytotoxic T cells.

1994 • 42 citations

Leukocyte-mediated lysis of infected hepatocytes during listeriosis occurs in mice depleted of NK cells or CD4+ CD8+ Thy1.2+ T cells

1993 • 31 citations

Restricted replication of Listeria monocytogenes in a gamma interferon-activated murine hepatocyte line

1995 • 30 citations

Immunity to bacteria

1990 • 22 citations

Kupffer Cell Engraftment Across the Major Histocompatibility Barrier in Mice

1990 • 20 citations

Terminal maturation of resting B cells by proliferation-independent B cells differentiation factors.

1986 • 17 citations

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