Topical opioids in mice: analgesia and reversal of tolerance by a topical N-methyl-D-aspartate antagonist.

Peripheral Mechanisms of Opioid Analgesia

1993 • 554 citations

Localization and activation of glutamate receptors in unmyelinated axons of rat glabrous skin

1995 • 358 citations

Blockade of tolerance to morphine but not to kappa opioids by a nitric oxide synthase inhibitor.

1993 • 282 citations

Intraarticular Morphine, Bupivacaine, and Morphine/Bupivacaine for Pain Control after Knee Videoarthroscopy

1992 • 256 citations

Opioid analgesia at peripheral sites: a target for opioids released during stress and inflammation?

1987 • 228 citations

Peripheral administration of NMDA, AMPA or KA results in pain behaviors in rats

1996 • 227 citations

Comparison of Postoperative Analgesic Effects of Intraarticular Bupivacaine and Morphine Following Arthroscopic Knee Surgery

1992 • 205 citations

Peripheral NMDA and non-NMDA glutamate receptors contribute to nociceptive behaviors in the rat formalin test

1997 • 205 citations

Analgesic Effect of Intraarticular Bupivacaine or Morphine After Arthroscopic Knee Surgery

1992 • 193 citations

Inhibition of opiate tolerance by non-competitive N-d-aspartate receptor antagonists

1994 • 191 citations

Novel receptor mechanisms for heroin and morphine-6β-glucuronide analgesia

1996 • 160 citations

The NMDA receptor antagonist MK-801 prevents long-lasting non-associative morphine tolerance in the rat

1992 • 155 citations

Opioid agonists and antagonists: An evaluation of their peripheral actions in inflammation

1992 • 139 citations

MK-801 inhibits the development of morphine tolerance at spinal sites

1993 • 98 citations

Peripheral morphine analgesia: synergy with central sites and a target of morphine tolerance.

1996 • 94 citations

Local Analgesia without Anesthesia Using Peripheral Perineural Morphine Injections

1987 • 93 citations

Peripheral Opioid Receptors

1995 • 81 citations

Low-dose intra-articular morphine analgesia in day case knee arthroscopy: A randomized double-blinded prospective study

1994 • 79 citations

3‐Methoxynaltrexone, a selective heroin/morphine‐6β‐glucuronide antagonist

1997 • 78 citations

Tolerance to morphine analgesia: decreased multiplicative interaction between spinal and supraspinal sites

1984 • 74 citations

Lidocaine Local Anesthesia for Arthroscopic Knee Surgery

1990 • 68 citations

Independent expression of two pharmacologically distinct supraspinal mu analgesic systems in genetically different mouse strains.

1993 • 57 citations

Role of opioids in peripheral analgesia

1992 • 39 citations

Synthesis and characterization of [125I]3′-(−)-iodopentazocine, a selective σ1 receptor ligand

1997 • 14 citations