The alternatively initiated c-Myc proteins differentially regulate transcription through a noncanonical DNA-binding site.

A new technique for the assay of infectivity of human adenovirus 5 DNA

1973 • 9,740 citations

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

Induction of apoptosis in fibroblasts by c-myc protein

1992 • 2,977 citations

Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes

1983 • 2,871 citations

Regulated expression of three C/EBP isoforms during adipose conversion of 3T3-L1 cells.

1991 • 1,684 citations

Max: A Helix-Loop-Helix Zipper Protein That Forms a Sequence-Specific DNA-Binding Complex with Myc

1991 • 1,650 citations

A nuclear factor for IL-6 expression (NF-IL6) is a member of a C/EBP family.

1990 • 1,517 citations

Adenovirus early region 1A enables viral and cellular transforming genes to transform primary cells in culture

1983 • 1,358 citations

Sequence-Specific DNA Binding by the c-Myc Protein

1990 • 893 citations

Constitutive c-myc expression in an IL-3-dependent myeloid cell line suppresses cell cycle arrest and accelerates apoptosis.

1991 • 861 citations

The MyoD DNA binding domain contains a recognition code for muscle-specific gene activation

1990 • 794 citations

Mxi1, a protein that specifically interacts with Max to bind Myc-Max recognition sites

1993 • 786 citations

The ornithine decarboxylase gene is a transcriptional target of c-Myc.

1993 • 759 citations

CCAAT-Enhancer Binding Protein: A Component of a Differentiation Switch

1991 • 733 citations

THE myc ONCOGENE: ITS ROLE IN TRANSFORMATION AND DIFFERENTIATION

1986 • 714 citations

Mad: A heterodimeric partner for Max that antagonizes Myc transcriptional activity

1993 • 711 citations

Control of c-myc Regulation in Normal and Neoplastic Cells

1991 • 632 citations

Methylation-Sensitive Sequence-Specific DNA Binding by the c-Myc Basic Region

1991 • 596 citations

The adenovirus major late transcription factor USF is a member of the helix-loop-helix group of regulatory proteins and binds to DNA as a dimer.

1990 • 584 citations

Association of Myn, the murine homolog of Max, with c-Myc stimulates methylation-sensitive DNA binding and ras cotransformation

1991 • 576 citations

Oncogenic activity of the c-Myc protein requires dimerization with Max

1993 • 543 citations

Proteins encoded by the human c-myc oncogene: differential expression in neoplastic cells.

1984 • 502 citations

New light on Myc and Myb. Part II. Myb.

1990 • 487 citations

TFE3: a helix-loop-helix protein that activates transcription through the immunoglobulin enhancer muE3 motif.

1990 • 484 citations

A non-AUG translational initiation in c-myc exon 1 generates an N-terminally distinct protein whose synthesis is disrupted in Burkitt's lymphomas

1988 • 481 citations

Myc and Max proteins possess distinct transcriptional activities

1992 • 478 citations

Definition of regions in human c-myc that are involved in transformation and nuclear localization.

1987 • 457 citations

An amino-terminal c-myc domain required for neoplastic transformation activates transcription.

1990 • 413 citations

Calcium-Regulated Phosphorylation Within the Leucine Zipper of C/EBPβ

1992 • 398 citations

Binding of myc proteins to canonical and noncanonical DNA sequences.

1993 • 375 citations

Adenovirus E1a proteins repress transcription from the SV40 early promoter

1985 • 366 citations

Translation Initiation at Non-Aug Triplets in Mammalian Cells

1989 • 363 citations

Transcription factor AP-4 contains multiple dimerization domains that regulate dimer specificity.

1990 • 330 citations

New light on Myc and Myb. Part I. Myc.

1990 • 325 citations

Mutations that disrupt DNA binding and dimer formation in the E47 helix-loop-helix protein map to distinct domains.

1990 • 316 citations

Proteins encoded by v-myc and c-myc oncogenes: Identification and localization in acute leukemia virus transformants and bursal lymphoma cell lines

1983 • 297 citations

Reciprocal Regulation of Adipogenesis by Myc and C/EBPα

1992 • 296 citations

Mutations at a Zn(II) finger motif in the yeast elF-2β gene alter ribosomal start-site selection during the scanning process

1988 • 283 citations

Max: functional domains and interaction with c-Myc.

1992 • 280 citations

Inhibition of Transcriptional Regulator Yin-Yang-1 by Association with c-Myc

1993 • 273 citations

Ig/EBP-1: a ubiquitously expressed immunoglobulin enhancer binding protein that is similar to C/EBP and heterodimerizes with C/EBP.

1990 • 272 citations

Activation of the c-fos gene by UV and phorbol ester: different signal transduction pathways converge to the same enhancer element.

1988 • 271 citations

Fluorographic detection of radioactivity in polyacrylamide gels with 2,5-diphenyloxazole in acetic acid and its comparison with existing procedures

1983 • 264 citations

Repression of cyclin D1: a novel function of MYC.

1994 • 250 citations

Direct role for Myc in transcription initiation mediated by interactions with TFII-I

1993 • 246 citations

A helix-loop-helix protein related to the immunoglobulin E box-binding proteins.

1990 • 244 citations

Binding and Suppression of the Myc Transcriptional Activation Domain by p107

1994 • 242 citations

Casein kinase II inhibits the DNA-binding activity of Max homodimers but not Myc/Max heterodimers.

1992 • 230 citations

Bacterial beta-galactosidase as a marker of Rous sarcoma virus gene expression and replication.

1985 • 206 citations

Antibodies to Human c- myc Oncogene Product: Evidence of an Evolutionarily Conserved Protein Induced During Cell Proliferation

1984 • 200 citations

Involvement of the 'leucine zipper' region in the oligomerization and transforming activity of human c-myc protein

1989 • 198 citations

c-Myc trans-activates the p53 promoter through a required downstream CACGTG motif.

1993 • 186 citations

Determination of the c-MYC DNA-binding site.

1991 • 181 citations

Avian retroviral long terminal repeats bind CCAAT/enhancer-binding protein.

1989 • 160 citations

An embryonically expressed gene is a target for c-Myc regulation via the c-Myc-binding sequence.

1992 • 147 citations

TATA-binding protein and the retinoblastoma gene product bind to overlapping epitopes on c-Myc and adenovirus E1A protein.

1993 • 146 citations

Opposite regulation of gene transcription and cell proliferation by c-Myc and Max.

1993 • 146 citations

Alternative Forms of Max as Enhancers or Suppressors of Myc-Ras Cotransformation

1992 • 130 citations

Human proto-oncogene N-myc encodes nuclear proteins that bind DNA.

1986 • 120 citations

Translational activation of the non-AUG-initiated c-myc 1 protein at high cell densities due to methionine deprivation.

1992 • 106 citations

Max and c-Myc/Max DNA-binding activities in cell extracts.

1992 • 94 citations

At least two nuclear proteins bind specifically to the Rous sarcoma virus long terminal repeat enhancer.

1987 • 83 citations

Enhanced translation and increased turnover of c-myc proteins occur during differentiation of murine erythroleukemia cells.

1990 • 79 citations

Intracellular Association of the Protein Product of the c-myc Oncogene with the TATA-Binding Protein

1994 • 78 citations

Multiple forms of C/EBP beta bind the EFII enhancer sequence in the Rous sarcoma virus long terminal repeat.

1994 • 54 citations

Mutational analysis of Max: role of basic, helix-loop-helix/leucine zipper domains in DNA binding, dimerization and regulation of Myc-mediated transcriptional activation.

1992 • 53 citations

Rous sarcoma virus enhancer factor I is a ubiquitous CCAAT transcription factor highly related to CBF and NF-Y.

1990 • 48 citations

B-myc inhibits neoplastic transformation and transcriptional activation by c-myc.

1993 • 47 citations

Functional analysis of the AUG- and CUG-initiated forms of the c-Myc protein.

1994 • 45 citations

c-myc products trans-activate the adenovirus E4 promoter in EC stem cells by using the same target sequence as E1A products

1988 • 35 citations

Maximal serum stimulation of the c-fos serum response element requires both the serum response factor and a novel binding factor, SRE-binding protein.

1992 • 35 citations

Identification of a third protein factor which binds to the rous sarcoma virus LTR enhancer: Possible homology with the serum response factor

1990 • 29 citations

a1/EBP: a leucine zipper protein that binds CCAAT/enhancer elements in the avian leukosis virus long terminal repeat enhancer

1992 • 26 citations

Characterization of nuclear proteins that bind the EFII enhancer sequence in the Rous sarcoma virus long terminal repeat

1992 • 23 citations

A complex pattern of translational initiation and phosphorylation in L-myc proteins.

1991 • 19 citations

Overproduction of v-Myc in the Nucleus and Its Excess Over Max Are Not Required for Avian Fibroblast Transformation

1993 • 13 citations