c-myc products trans-activate the adenovirus E4 promoter in EC stem cells by using the same target sequence as E1A products

Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes

1983 • 2,871 citations

Identification of a cyclic-AMP-responsive element within the rat somatostatin gene.

1986 • 1,424 citations

The Rous sarcoma virus long terminal repeat is a strong promoter when introduced into a variety of eukaryotic cells by DNA-mediated transfection.

1982 • 1,371 citations

Adenovirus early region 1A enables viral and cellular transforming genes to transform primary cells in culture

1983 • 1,358 citations

Cell-cycle control of c-myc but not c-ras expression is lost following chemical transformation

1984 • 785 citations

Proteins encoded by the human c-myc oncogene: differential expression in neoplastic cells.

1984 • 502 citations

A non-AUG translational initiation in c-myc exon 1 generates an N-terminally distinct protein whose synthesis is disrupted in Burkitt's lymphomas

1988 • 481 citations

ADENOVIRUS PROMOTERS AND E1A TRANSACTIVATION

1986 • 460 citations

Induction of the synthesis of a 70,000 dalton mammalian heat shock protein by the adenovirus E1A gene product

1982 • 454 citations

Detailed analysis of the mouse H-2Kb promoter: Enhancer-like sequences and their role in the regulation of class I gene expression

1986 • 395 citations

Common Control of the Heat Shock Gene and Early Adenovirus Genes: Evidence for a Cellular E1A-like Activity

1984 • 331 citations

A cellular protein, activating transcription factor, activates transcription of multiple E1A-inducible adenovirus early promoters.

1987 • 284 citations

Activation of gene expression by adenovirus and herpesvirus regulatory genes acting in trans and by a cis-acting adenovirus enhancer element

1983 • 250 citations

A cellular transcription factor E4F1 interacts with an E1a-inducible enhancer and mediates constitutive enhancer function in vitro.

1987 • 208 citations

Nucleotide sequence of the human c-myc locus: provocative open reading frame within the first exon.

1984 • 207 citations

Identification of factors that interact with the E1A-inducible adenovirus E3 promoter.

1987 • 189 citations

The protein products of the myc and myb oncogenes and adenovirus E1a are structurally related

1983 • 178 citations

Transcription Control by Oncogenes

1985 • 176 citations

Activation and repression of mammalian gene expression by the c-myc protein.

1987 • 144 citations

Proteins Encoded by the Human c-myc Oncogene: Differential Expression in Neoplastic Cells

1984 • 138 citations

Identification of an E1A-inducible cellular factor that interacts with regulatory sequences within the adenovirus E4 promoter.

1987 • 133 citations

Developmental control of a promoter-specific factor that is also regulated by the E1A gene product

1987 • 120 citations

Multiple Basal Elements of a Human hsp7O Promoter Function Differently in Human and Rodent Cell Lines

1987 • 119 citations

Adenovirus E1a Gene Product Expressed at High Levels in Escherichia coli Is Functional

1984 • 111 citations

The E4 transcilpilonal unit of Ad2: far upstream sequences are required for its transactivation by E1A

1984 • 86 citations

Functional Relation Between HTLV-II x and Adenovirus E1A Proteins in Transcriptional Activation

1985 • 75 citations

Identification of Two Transcription Factors That Bind to Specific Elements in the Promoter of the Adenovirus Early-Region 4

1988 • 57 citations

Far upstream sequences are required for efficient transcription from the adenovirus-2 E1A transcription unit

1983 • 42 citations

The E4 promoter of adenovirus type 2 contains an E1A dependent cis-actlng element

1986 • 42 citations