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Species differences in response to trichloroethylene

Data up to Jan 2025

Published1985
Citations127
References40

Total Citations Per Year

Abstract

References (40)

Methods in Enzymology , Vol

1966 • 26,261 citations

Hypolipidaemic hepatic peroxisome proliferators form a novel class of chemical carcinogens

1980 • 854 citations

NATURE OF THE HEPATOMEGALIC EFFECT PRODUCED BY ETHYL-CHLOROPHENOXY-ISOBUTYRATE IN THE RAT

1965 • 599 citations

In vivo covalent binding of organic chemicals to DNA as a quantitative indicator in the process of chemical carcinogenesis

1979 • 412 citations

MICROBODIES IN EXPERIMENTALLY ALTERED CELLS

1967 • 234 citations

Mutagenicity in vitro and potential carcinogenicity of chlorinated ethylenes as a function of metabolic oxirane formation

1975 • 232 citations

Hepatic peroxisome (microbody) proliferation in rats fed plasticizers and related compounds

1978 • 224 citations

Oxidation of trichloroethylene by liver microsomal cytochrome P-450: evidence for chlorine migration in a transition state not involving trichloroethylene oxide

1982 • 215 citations

Biliary excretion of foreign compounds. Biphenyl, stilboestrol and phenolphthalein in the rat: molecular weight, polarity and metabolism as factors in biliary excretion

1967 • 168 citations

Species differences in response to trichloroethylene

1985 • 144 citations

Young Scientists Award Lecture 1984: Species Differences in Carcinogenicity and Peroxisome Proliferation due to Trichloroethylene: A Biochemical Human Hazard Assessment

1985 • 139 citations

The metabolism of 36Cl-labelled trichloroethylene and tetrachloroethylene in the rat

1963 • 134 citations

Chemical reactivity, metabolic oxirane formation and biological reactivity of chlorinated ethylenes in the isolated perfused rat liver preparation

1975 • 128 citations

The pharmacokinetics and macromolecular interactions of trichloroethylene in mice and rats

1982 • 119 citations

Metabolism of trichloroethylene in liver microsomes. II. Identification of the reaction product as chloral hydrate.

1965 • 86 citations

ChemInform Abstract: HYPOLIPIDEMIC HEPATIC PEROXISOME PROLIFERATORS FORM A NOVEL CLASS OF CHEMICAL CARCINOGENS

1980 • 85 citations

Covalent interaction of metabolites of the carcinogen trichloroethylene in rat hepatic microsomes.

1976 • 81 citations

Excretion of Trichloroethylene Metabolites in Human Urine

1960 • 78 citations

Carcinogenesis bioassay of trichloroethylene.

1976 • 76 citations

Metabolic activation of trichloroethylene into a chemically reactive metabolite toxic to the liver.

1978 • 72 citations

Irreversible binding of chlorinated ethylenes to macromolecules

1977 • 71 citations

Bioassay of tetrachloroethylene for possible carcinogenicity.

1977 • 69 citations

Covalent binding of the carcinogen trichloroethylene to hepatic microsomal proteins and to exogenous DNA in vitro.

1978 • 67 citations

Consideration of the evidence for mechanisms of 1,1,2-trichloroethylene metabolism, including new identification of its dichloroacetic acid and trichloroacetic acid metabolites in mice

1980 • 66 citations

Metabolic activation of chlorinated ethylenes: dependence of mutagenic effect on electrophilic reactivity of the metabolically formed epoxides

1977 • 63 citations

Reactions of trichloroethylene epoxide in aqueous systems

1979 • 60 citations

Irreversible binding of 14C-labelled trichloroethylene to mice liver constituents in vivo and in vitro

1977 • 53 citations

Metabolic transformations of trichlorethylene.

1949 • 52 citations

Spectral evidence for 2,2,3-trichloro-oxirane formation during microsomal trichloroethylene oxidation

1977 • 48 citations

Metabolism of [14C]trichloroethylene to14CO2and interaction of a metabolite with liver DNA in rats and mice

1982 • 46 citations

Trichloroethylene: Its interaction with hepatic microsomal cytochrome P-450 in vitro

1980 • 41 citations

Gas chromatography and mass spectrometry of some trimethylsilyl derivatives of urinary glucuronides

1974 • 31 citations

Measurement of chloral hydrate, trichloroethanol, trichloroacetic acid and monochloroacetic acid in the serum and the urine by gas chromatography

1974 • 28 citations

Incubation of 14C-trichloroethylene vapor with rat liver microsomes: Uptake of radioactivity and covalent protein binding of metabolites

1977 • 27 citations

IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans: some monomers, plastics and synthetic elastomers, and acrolein.

1979 • 23 citations

TCA [sodium trichloroacetate] metabolism by soil microorganisms

1969 • 18 citations

Comparative metabolism of [14C] trichloroethylene in chimpanzees, baboons, and rhesus monkeys

1982 • 16 citations

Carcinogenic potential of chlorinated ethylenes tentative molecular rules.

1976 • 15 citations

CONVERSION OF TRICHLOROETHYLENE TO CARBON MONOXIDE BY MICROSOMAL CYTOCHROME P450

1977 • 7 citations

Pathway and rate of metabolism of trichloroethylene in rats and rabbits.

1979 • 6 citations

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