The radiation response of V79 and human tumour multicellular spheroids – cell survival and growth delay studies

A simplified method for production and growth of multicellular tumor spheroids.

1977 • 501 citations

An in vitro colony assay for human tumours grown in immune-suppressed mice and treated in vivo with cytotoxic agents

1978 • 296 citations

Effects of intercellular contact on repair of radiation damage

1972 • 287 citations

A soft agar colony assay for Lewis lung tumour and B16 melanoma taken directly from the mouse

1976 • 135 citations

Improved immune-suppression techniques for the xenografting of human tumours

1978 • 131 citations

Cellular repair factors influencing radiocurability of human malignant tumours

1982 • 108 citations

Proliferation and viability in cellular spheroids of human origin.

1978 • 106 citations

The therapeutic response of three human tumor lines maintained in immune-suppressed mice.

1975 • 98 citations

Hypoxic Cells in anin VitroTumour Model

1973 • 96 citations

CELL CYCLE KINETICS IN AN IN VITRO TUMOR MODEL

1976 • 83 citations

Response to the RIF-1 tumor in vitro and in C3H/Km mice to X-radiation (cell survival, regrowth delay, and tumor control), chemotherapeutic agents, and activated macrophages.

1980 • 81 citations

Variable Radiobiological Responses of Spheroids

1980 • 76 citations

Polyfunctional Radiosensitizers: I. Effects of a Nitroxyl Biradical on the Survival of Mammalian Cells in Vitro

1976 • 68 citations

Dependence of the radiation response of an in vitro tumor model on cell cycle effects.

1973 • 65 citations

Interpretation of Survival-curve Data for Chinese Hamster Cells, Line V-79 Using the Multi-target, Multi-target with Initial Slope, and α, β Equations

1978 • 62 citations

Response to chemotherapy of EMT6 spheroids as measured by growth delay and cell survival

1980 • 47 citations

A Comparative Study of Post-irradiation Growth Kinetics of Spheroids and Monolayers

1975 • 42 citations

Relationship between Surviving Fractions Using the Colony Method, the LD 50 , and the Growth Delay after Irradiation of Human Melanoma Cells Grown as Multicellular Spheroids

1981 • 40 citations

Hypoxic Fraction and Repair of Potentially Lethal Radiation Damage in Two Human Melanomas Transplanted into Nude Mice

1981 • 33 citations

In vitro cytotoxic drug sensitivity testing of human tumour xenografts grown as multicellular tumour spheroids

1982 • 33 citations

Chemotherapy of human breast-carcinoma xenografts

1980 • 29 citations

ECTOPIC HORMONE PRODUCTION BY BRONCHIAL CARCINOMAS IN CULTURE

1976 • 24 citations

Intercellular communication, three-dimensional cell contact and radiosensitivity

1982 • 21 citations

Radiosensitivity of nall human melanoma transplanted into nude mice: Repair, reoxygenation and dose fractionation

1982 • 15 citations