CXCR4 Regulates Growth of Both Primary and Metastatic Breast Cancer

Involvement of chemokine receptors in breast cancer metastasis

2001 • 5,203 citations

A multigenic program mediating breast cancer metastasis to bone

2003 • 2,539 citations

Germline Transmission and Tissue-Specific Expression of Transgenes Delivered by Lentiviral Vectors

2002 • 2,019 citations

Molecular characterization of the tumor microenvironment in breast cancer

2004 • 1,278 citations

Selective events in the metastatic process defined by analysis of the sequential dissemination of subpopulations of a mouse mammary tumor.

1992 • 1,217 citations

Multistep Nature of Metastatic Inefficiency

1998 • 1,186 citations

Mouse 4T1 Breast Tumor Model

2000 • 826 citations

The membrane-cytoskeleton linker ezrin is necessary for osteosarcoma metastasis

2004 • 699 citations

Stromal-derived factor-1 in human tumors recruits and alters the function of plasmacytoid precursor dendritic cells

2001 • 644 citations

NF-κ B Promotes Breast Cancer Cell Migration and Metastasis by Inducing the Expression of the Chemokine Receptor CXCR4

2003 • 624 citations

A small-molecule antagonist of CXCR4 inhibits intracranial growth of primary brain tumors

2003 • 611 citations

Multiple Actions of the Chemokine CXCL12 on Epithelial Tumor Cells in Human Ovarian Cancer

2002 • 471 citations

The bicyclam AMD3100 story

2003 • 450 citations

The chemokine receptor CXCR4 is required for outgrowth of colon carcinoma micrometastases.

2003 • 431 citations

Vascular endothelial growth factor promotes breast carcinoma invasion in an autocrine manner by regulating the chemokine receptor CXCR4.

2002 • 428 citations

Angiogenesis and apoptosis

2003 • 419 citations

Reduction of established spontaneous mammary carcinoma metastases following immunotherapy with major histocompatibility complex class II and B7.1 cell-based tumor vaccines.

1998 • 388 citations

CXCR4 Is a Major Chemokine Receptor on Glioma Cells and Mediates Their Survival

2002 • 369 citations

Visualizing the kinetics of tumor-cell clearance in living animals

1999 • 358 citations

Inhibition of Breast Cancer Metastasis by Selective Synthetic Polypeptide against CXCR4

2004 • 340 citations

The chemokine SDF‐1, stromal cell‐derived factor 1, attracts early stage B cell precursors via the chemokine receptor CXCR4

1997 • 339 citations

Stromal Cell-Derived Factor 1, a Novel Target of Estrogen Receptor Action, Mediates the Mitogenic Effects of Estradiol in Ovarian and Breast Cancer Cells

2003 • 290 citations

T140 analogs as CXCR4 antagonists identified as anti‐metastatic agents in the treatment of breast cancer

2003 • 277 citations

Regulation of CXCR4-mediated chemotaxis and chemoinvasion of breast cancer cells

2004 • 273 citations

Apoptosis: an early event in metastatic inefficiency.

2001 • 268 citations

Expression pattern of CXC chemokine receptor-4 is correlated with lymph node metastasis in human invasive ductal carcinoma

2003 • 261 citations

A chemokine receptor antagonist inhibits experimental breast tumor growth.

2003 • 257 citations

The SDF‐1‐CXCR4 Axis Stimulates VEGF Secretion and Activates Integrins but does not Affect Proliferation and Survival in Lymphohematopoietic Cells

2001 • 221 citations

Noninvasive Bioluminescence Imaging of Herpes Simplex Virus Type 1 Infection and Therapy in Living Mice

2002 • 180 citations

Cooperativity of Staphylococcal aureus enterotoxin B superantigen, major histocompatibility complex class II, and CD80 for immunotherapy of advanced spontaneous metastases in a clinically relevant postoperative mouse breast cancer model.

2000 • 128 citations

The stromal cell–derived factor-1α/CXCR4 ligand–receptor axis is critical for progenitor survival and migration in the pancreas

2003 • 107 citations

Antiviral efficacy in vivo of the anti-human immunodeficiency virus bicyclam SDZ SID 791 (JM 3100), an inhibitor of infectious cell entry

1996 • 100 citations

Focus on breast cancer

2002 • 97 citations

The expression of the chemokine receptor CXCR3 and its ligand, CXCL10, in human breast adenocarcinoma cell lines

2004 • 90 citations

CXCR4 is Expressed in Ductal Carcinoma in situ of the Breast and in Atypical Ductal Hyperplasia

2004 • 75 citations

Overexpression of IRF9 confers resistance to antimicrotubule agents in breast cancer cells.

2001 • 75 citations

Characterization of Phosphine Complexes of Technetium(III) as Transport Substrates of the Multidrug Resistance P-Glycoprotein and Functional Markers of P-Glycoprotein at the Blood−Brain Barrier

1997 • 50 citations

Detection of Primary Lung Tumors in Rodents by Magnetic Resonance Imaging

2004 • 49 citations

Suradista NSC 651016 inhibits the angiogenic activity of CXCL12-stromal cell-derived factor 1alpha.

2002 • 13 citations